2017
Endocannabinoid Signaling in the Control of Social Behavior
Wei D, Allsop S, Tye K, Piomelli D. Endocannabinoid Signaling in the Control of Social Behavior. Trends In Neurosciences 2017, 40: 385-396. PMID: 28554687, PMCID: PMC5699224, DOI: 10.1016/j.tins.2017.04.005.Peer-Reviewed Original ResearchConceptsSocial behaviorEndocannabinoid signalingG-protein-coupled cannabinoid receptorsEndocannabinoid signaling systemComplex social groupsSocial anxietySocial impairmentNeural basisSocial rewardsCannabinoid receptorsNeural processesEndocannabinoidAnimal modelsEmergent insightsAnxietyRewardBehaviorSocial groupsImpairmentBrainSignaling systemAgonistsMammalian speciesReceptors
2014
Optogenetic insights on the relationship between anxiety-related behaviors and social deficits
Allsop S, Vander Weele C, Wichmann R, Tye K. Optogenetic insights on the relationship between anxiety-related behaviors and social deficits. Frontiers In Behavioral Neuroscience 2014, 8: 241. PMID: 25076878, PMCID: PMC4099964, DOI: 10.3389/fnbeh.2014.00241.Peer-Reviewed Original ResearchAnxiety-related behaviorAutism spectrum disorderAnxiety disordersSocial deficitsSocial behaviorBasolateral amygdalaVentral hippocampusSpectrum disorderPathogenesis of social anxiety disorderModulating anxiety-related behaviorsRates of co-morbiditySocial anxiety disorderModulate social behaviorPsychiatric disease statesNeural circuit mechanismsComplex emotional statesPsychiatric illnessPsychiatric diseasesInvestigation of neural circuitsCircuit mechanismsAnxietyNeural circuitsEmotional statesSocial domainsDeficits