2024
Adverse cardiovascular events and cardiac imaging findings in patients on immune checkpoint inhibitors
Kwan J, Shen M, Akhlaghi N, Hu J, Mora R, Cross J, Jiang M, Mankbadi M, Wang P, Zaman S, Lee S, Im Y, Feher A, Liu Y, S. S, Tao W, Wei W, Baldassarre L. Adverse cardiovascular events and cardiac imaging findings in patients on immune checkpoint inhibitors. PLOS ONE 2024, 19: e0314555. PMID: 39621799, PMCID: PMC11611253, DOI: 10.1371/journal.pone.0314555.Peer-Reviewed Original ResearchConceptsAdverse cardiovascular eventsICI therapyCardiac magnetic resonanceIncreased risk of mortalityICI initiationIncreased riskRisk of mortalityCentral nervous systemVentricular dysfunctionCancer patients treated with ICIsCardiovascular eventsLeft ventricular late gadolinium enhancementMortality benefitCardiovascular riskAbnormal left ventricular ejection fractionPatients treated with ICIsLeft ventricular ejection fractionCentral nervous system malignanciesRisk of adverse cardiovascular eventsImmune checkpoint inhibitorsRight ventricular dysfunctionGlobal longitudinal strainVentricular ejection fractionLeft ventricular dysfunctionMultimodality cardiac imaging
2016
Echocardiographic Linear Dimensions for Assessment of Right Ventricular Chamber Volume as Demonstrated by Cardiac Magnetic Resonance
Kim J, Srinivasan A, Seoane T, Di Franco A, Peskin CS, McQueen DM, Paul TK, Feher A, Geevarghese A, Rozenstrauch M, Devereux RB, Weinsaft JW. Echocardiographic Linear Dimensions for Assessment of Right Ventricular Chamber Volume as Demonstrated by Cardiac Magnetic Resonance. Journal Of The American Society Of Echocardiography 2016, 29: 861-870. PMID: 27297619, PMCID: PMC5057385, DOI: 10.1016/j.echo.2016.05.002.Peer-Reviewed Original ResearchConceptsRV end-diastolic volumeCardiac magnetic resonanceEnd-diastolic volumeRV end-systolic volumeEnd-systolic volumeRV lengthEchocardiographic dimensionsEnd-systolic dimensionCoronary artery diseaseRight ventricular structureRV chamber sizeAmerican SocietyVentricular chamber volumeRetrospective registryRV dilationArtery diseaseRV sizeRV dimensionsObtainable markerVentricular structureRV volumesEchocardiographyMagnetic resonanceFour-chamberAxis viewAssociation of Right Ventricular Pressure and Volume Overload with Non-Ischemic Septal Fibrosis on Cardiac Magnetic Resonance
Kim J, Medicherla CB, L. C, Feher A, Kukar N, Geevarghese A, Goyal P, Horn E, Devereux RB, Weinsaft JW. Association of Right Ventricular Pressure and Volume Overload with Non-Ischemic Septal Fibrosis on Cardiac Magnetic Resonance. PLOS ONE 2016, 11: e0147349. PMID: 26799498, PMCID: PMC4723145, DOI: 10.1371/journal.pone.0147349.Peer-Reviewed Original ResearchConceptsPulmonary artery systolic pressureNon-ischaemic fibrosisCardiac magnetic resonanceRV dysfunctionAdverse right ventricular (RV) remodelingRV end-systolic volumeWall stressRV pressure loadRV wall stressRight ventricular remodelingRight ventricular pressureEnd-systolic volumeLower RVEFSimilar LVEFLV dysfunctionRV dilationRV sizeSeptal fibrosisMultivariable analysisSystolic pressureVolume overloadChamber dilationPoor prognosisTransthoracic echoVentricular remodeling