1997
GroEL‐Mediated protein folding
Fenton W, Horwich A. GroEL‐Mediated protein folding. Protein Science 1997, 6: 743-760. PMID: 9098884, PMCID: PMC2144759, DOI: 10.1002/pro.5560060401.Peer-Reviewed Original ResearchConceptsGroEL-GroESNonnative polypeptidesSubstrate proteinsATP bindingProtein foldingHomologous proteinsNonnative formsPrimary structureConformational changesGroELTernary complexPolypeptideAssociation 5FoldingProteinBindingChaperonesGroESConformationEnergy landscapeRole of hydrophobicityPathway 3RolePathwayComplex C.
1991
Mitochondrial protein import.
Horwich A, Cheng M, West A, Pollock R. Mitochondrial protein import. Current Topics In Microbiology And Immunology 1991, 170: 1-42. PMID: 1760928, DOI: 10.1007/978-3-642-76389-2_1.Peer-Reviewed Original ResearchConceptsMitochondrial protein import pathwayProtein import pathwayPrecise molecular functionConformational alterationsImport pathwayMolecular functionsStep of recognitionMembrane translocationProteolytic cleavageProteinTranslocationDynamic picturePowerful toolGeneticsAlterationsPathwayBiochemistryCleavageCritical features