1998
The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus
Kaffman A, Rank N, O'Neill E, Huang L, O'Shea E. The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus. Nature 1998, 396: 482-486. PMID: 9853758, DOI: 10.1038/24898.Peer-Reviewed Original ResearchMeSH KeywordsBiological TransportCell NucleusCloning, MolecularCytoplasmDNA-Binding ProteinsEscherichia coliFungal ProteinsGTP PhosphohydrolasesKaryopherinsMutationNuclear ProteinsPhosphorylationProtein BindingRan GTP-Binding ProteinReceptors, Cytoplasmic and NuclearSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsConceptsTranscription factor Pho4Nuclear exportYeast transcription factor Pho4Phosphorylation of Pho4Cyclin-dependent kinasesPho80-Pho85Yeast RanProtein exportPho4Transcription factorsReplication factorsPhosphate availabilityPhosphorylationMsn5ProteinKinaseNuclear complexNucleus2ExportNucleusCyclinGTPCytoplasmBindsMechanism
1994
Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85
Kaffman A, Herskowitz I, Tjian R, O'Shea E. Phosphorylation of the Transcription Factor PHO4 by a Cyclin-CDK Complex, PHO80-PHO85. Science 1994, 263: 1153-1156. PMID: 8108735, DOI: 10.1126/science.8108735.Peer-Reviewed Original ResearchMeSH KeywordsAcid PhosphataseAmino Acid SequenceCulture MediaCyclin-Dependent KinasesCyclinsDNA-Binding ProteinsFungal ProteinsGene Expression Regulation, FungalModels, GeneticMolecular Sequence DataPhosphatesPhosphorylationRepressor ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsConceptsCyclin-CDK complexesTranscription factor Pho4Cell cycle controlPho80-Pho85PHO5 transcriptionPho4Protein kinaseYeast cyclinNegative regulationRelevant substratesPHO80PHO2PHO5Regulatory processesPhosphorylationComplexesPho85TranscriptionHomologyKinaseHigh phosphateCyclinInteractsRegulationInduction