2020
Effect of Microfracture on Functional Outcomes and Subchondral Sclerosis Following Distraction Arthroplasty of the Ankle Joint
Gianakos A, Haring R, Shimozono Y, Fragomen A, Kennedy J. Effect of Microfracture on Functional Outcomes and Subchondral Sclerosis Following Distraction Arthroplasty of the Ankle Joint. Foot & Ankle International 2020, 41: 631-638. PMID: 32354229, DOI: 10.1177/1071100720917144.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnkle JointArthroplasty, SubchondralFemaleHumansMaleMiddle AgedOsteoarthritisSclerosisConceptsPost-traumatic osteoarthritisDistraction arthroplastyAnkle jointOutcomes of patientsAnkle Outcome ScoreFunctional activity levelBone marrow aspirateFAOS scoresOutcome scoresFunctional outcomeAnkle arthrodesisSubchondral sclerosisBiologic augmentationMarrow aspiratesPatientsLevel IIIPoor candidatesDemographic dataJoint replacementEnd stageArthroplastyAdverse effectsRole of microfracturesActivity levelsSame time interval
2018
Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis
Hurley E, Yasui Y, Gianakos A, Seow D, Shimozono Y, Kerkhoffs G, Kennedy J. Limited evidence for adipose‐derived stem cell therapy on the treatment of osteoarthritis. Knee Surgery, Sports Traumatology, Arthroscopy 2018, 26: 3499-3507. PMID: 29713784, DOI: 10.1007/s00167-018-4955-x.Peer-Reviewed Original ResearchConceptsStromal vascular fractionPlatelet-rich plasmaTreatment of osteoarthritisClinical outcomesSystematic reviewForm of SVFUse of SVFAdipose-derived stem cell therapyEffects of ADSCsIncidence of swellingFavorable clinical outcomeLevel IV studiesCochrane Library databasesEffects of AdiposeDonor siteStem cell therapySVF injectionComplication rateBiological adjuvantsClinical studiesLevel IVExclusion criteriaLibrary databasesSide effectsAdipose tissue