2017
Clinical application of concentrated bone marrow aspirate in orthopaedics: A systematic review
Gianakos A, Sun L, Patel J, Adams D, Liporace F. Clinical application of concentrated bone marrow aspirate in orthopaedics: A systematic review. World Journal Of Orthopedics 2017, 8: 491-506. PMID: 28660142, PMCID: PMC5478493, DOI: 10.5312/wjo.v8.i6.491.Peer-Reviewed Original ResearchConcentrated bone marrow aspirateBone marrow aspirateTendon repairTendon injuriesMarrow aspiratesCartilaginous lesionsSystematic reviewClinical settingFull-thickness chondral lesionsSignificant clinical improvementQuality of evidenceInclusion/exclusion criteriaLevel of evidenceStandardized outcome measuresMagnetic resonance imagingClinical improvementAdjunctive treatmentBone unionDecreased riskLower incidenceChondral lesionsOutcome measuresExclusion criteriaHealing rateOsteochondral lesions
2016
Treatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: a Systematic Review of Randomized Control Trials
Villa J, Husain S, van der List J, Gianakos A, Lane J. Treatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: a Systematic Review of Randomized Control Trials. HSS Journal ® 2016, 12: 261-271. PMID: 27703421, PMCID: PMC5026659, DOI: 10.1007/s11420-016-9505-9.Peer-Reviewed Original ResearchRandomized clinical trialsFemoral head collapseBone marrow mesenchymal cellsCore decompressionPre-collapse ONFHHead collapseLower riskFemoral headSystematic reviewLow-level evidence studiesMore RCTsQuestions/PurposesThe purposeNew combination therapiesMeta-Analyses (PRISMA) guidelinesRandomized control trialStandardized outcome measuresPreferred Reporting ItemsPre-collapse stageMethodsUsing PubMedRadiologic outcomesBisphosphonate treatmentClinical evidenceMarrow mesenchymal cellsCombination therapyFunctional outcome