2018
Update on the Comprehensive Approach to Fragility Fractures
Cohn M, Gianakos A, Grueter K, Rosen N, Cong G, Lane J. Update on the Comprehensive Approach to Fragility Fractures. Journal Of Orthopaedic Trauma 2018, 32: 480-490. PMID: 30036208, DOI: 10.1097/bot.0000000000001244.Peer-Reviewed Original ResearchConceptsFragility fracturesAnabolic agentsDual-energy x-ray absorptiometry screeningFracture Liaison Service (FLS) modelNew anabolic agentsFirst-line treatmentFracture liaison serviceBone density lossAntiosteoporotic medicationAntiresorptive agentsNonpharmacologic treatmentsFracture careVitamin DSurgical historyTreatment optionsAntisclerostin antibodiesBone densityBone diseaseEffective treatmentLiaison servicePhysician extendersFracture healingPotential treatmentDensity lossTreatment
2015
Bisphosphonate Treatment in Osteoporosis: Optimal Duration of Therapy and the Incorporation of a Drug Holiday
Villa J, Gianakos A, Lane J. Bisphosphonate Treatment in Osteoporosis: Optimal Duration of Therapy and the Incorporation of a Drug Holiday. HSS Journal ® 2015, 12: 66-73. PMID: 26855630, PMCID: PMC4733702, DOI: 10.1007/s11420-015-9469-1.Peer-Reviewed Original ResearchRecent fragility fractureDrug holidayBisphosphonate treatmentFragility fracturesBone deficiencyQuestions/PurposesThe purposeHigh fracture riskBone turnover rateRisk of fractureBone mass measurementsBisphosphonate therapyDrug discontinuationPeer-reviewed journalsCase seriesDrug therapyFracture riskPurposesThe purposeClinical trialsInclusion criteriaCase controlExclusion criteriaMethodsA reviewHuman studiesPatientsElectronic databasesOsteoporosis and Hip Fractures
Olgun D, Gianakos A, Jo J, Galmer L, Lane J. Osteoporosis and Hip Fractures. 2015, 141-158. DOI: 10.1007/978-3-319-19905-4_8.Peer-Reviewed Original ResearchHip fractureFragility fracturesFragility fracture risk factorsOsteoporosis-related fragility fracturesMajor public health concernFracture risk factorsFracture liaison serviceMajority of patientsOsteoporotic fragility fracturesResidual functional impairmentOsteoporotic hip fracturesPublic health concernOsteoporosis managementPatient mortalityRisk factorsPatient outcomesPharmacological strategiesFunctional impairmentLiaison serviceSubsequent fracturesGreater riskHealth concernHealthcare expendituresOsteoporosisBone evaluation