2016
Bone Marrow Aspirate Concentrate in Animal Long Bone Healing
Gianakos A, Ni A, Zambrana L, Kennedy J, Lane J. Bone Marrow Aspirate Concentrate in Animal Long Bone Healing. Journal Of Orthopaedic Trauma 2016, 30: 1-9. PMID: 26371620, DOI: 10.1097/bot.0000000000000453.Peer-Reviewed Original ResearchConceptsBone marrow aspirate concentrateBone healingLong bone healingBone mesenchymal stem cellsUse of BMACConfer beneficial effectsLong bone fracturesPubMed/MEDLINESegmental defectsSignificant increaseEarly bone healingBMAC groupEmbase databasesComputed tomographyBone fracturesHistomorphometric assessmentMesenchymal stem cellsBone areaBeneficial effectsVivo evidenceBone formationVivo studiesLong bonesConfidence intervalsHealing
2015
Platelet-Rich Plasma in the Animal Long-Bone Model: An Analysis of Basic Science Evidence.
Gianakos A, Zambrana L, Savage-Elliott I, Lane J, Kennedy J. Platelet-Rich Plasma in the Animal Long-Bone Model: An Analysis of Basic Science Evidence. Orthopedics 2015, 38: e1079-90. PMID: 26652328, DOI: 10.3928/01477447-20151120-04.Peer-Reviewed Original ResearchConceptsPlatelet-rich plasmaEffect of PRPPercent of studiesLong bone modelsUse of PRPPlatelet concentrationBasic science evidencePubMed/MEDLINESignificant increaseEarly bone healingAdditional treatment variablesPeer-reviewed journalsCase seriesLong bone healingPRP groupEmbase databasesBlood productsClinical studiesHistomorphometric assessmentBone pathologyBone areaPlatelet productsBone healingBeneficial effectsVivo evidence