1995
A Role for Calcineurin (Protein Phosphatase-2B) in the Regulation of Glutamate Release
Sihra T, Nairn A, Kloppenburg P, Lin Z, Pouzat C. A Role for Calcineurin (Protein Phosphatase-2B) in the Regulation of Glutamate Release. Biochemical And Biophysical Research Communications 1995, 212: 609-616. PMID: 7542882, DOI: 10.1006/bbrc.1995.2013.Peer-Reviewed Original ResearchConceptsRelease of glutamateGlutamate releaseVoltage-dependent Ca channel activityVoltage-dependent Ca influxRat cerebral cortexCa-dependent componentCa channel activityCerebral cortexNerve terminalsCa influxInflux of CaCa entryActivation of calcineurinCa channelsCalcineurin activityGlutamateFK506CalcineurinRelease
1990
Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes
Nichols R, Sihra T, Czernik A, Nairn A, Greengard P. Calcium/calmodulin-dependent protein kinase II increases glutamate and noradrenaline release from synaptosomes. Nature 1990, 343: 647-651. PMID: 2154695, DOI: 10.1038/343647a0.Peer-Reviewed Original ResearchConceptsNeurotransmitter releaseRat brain synaptosomesSquid giant synapseRelease of neurotransmittersNoradrenaline releaseGlutamate releaseNerve terminalsBrain synaptosomesNervous systemUnidentified neurotransmitterGiant synapseDependent protein kinase IIVertebrate nervous systemRats calciumProtein kinase IINeurotransmittersInduced releasePK IISynaptosomesCalcium-dependent protein phosphorylationGlutamateKinase IIReleaseNoradrenalineInitial rate