2017
The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes
Djenoune L, Desban L, Gomez J, Sternberg JR, Prendergast A, Langui D, Quan FB, Marnas H, Auer TO, Rio JP, Del Bene F, Bardet PL, Wyart C. The dual developmental origin of spinal cerebrospinal fluid-contacting neurons gives rise to distinct functional subtypes. Scientific Reports 2017, 7: 719. PMID: 28389647, PMCID: PMC5428266, DOI: 10.1038/s41598-017-00350-1.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedAxonsBiomarkersCarrier ProteinsCell DifferentiationCerebrospinal FluidFluorescent Antibody TechniqueGanglia, SpinalHomozygoteMutationNeuronsSensory Receptor CellsSignal TransductionSpinal CordSpinal Nerve RootsTRPP Cation ChannelsZebrafishZebrafish ProteinsConceptsDual developmental originDevelopmental originsDistinct progenitor domainsApical extensionDistinct functional subtypesDifferent developmental originsCerebrospinal fluid-contacting neuronsTranscription factorsMechanical cuesZebrafish larvaeDistinct functionsProgenitor domainsCentral nervous systemCell typesDistinct cascadesFunctional populationsDifferent functional propertiesCSF-cNsNovel avenuesPKD2L1 channelFunctional subtypesSensory neuronsNeuronal targetsDistinct functional populationsSpecific markers
2014
Chapter 13 Neural Crest Cells and Peripheral Nervous System Development
Prendergast A, Raible D. Chapter 13 Neural Crest Cells and Peripheral Nervous System Development. 2014, 255-286. DOI: 10.1016/b978-0-12-401730-6.00014-4.Peer-Reviewed Original ResearchTrunk neural crestNeural crestDorsal root gangliaPeripheral nervous systemTranscription factor cascadeCell fate decisionsMultipotent cell populationPeripheral nervous system developmentGene regulatory networksNeural crest cellsNervous system developmentFate decisionsRegulatory networksTranscription factorsCrest cellsCell typesNeuronal subtypesSympathetic chain gangliaSequential cascadeCell populationsChain gangliaRoot gangliaTrk receptorsSympathetic neuronsExpression
2008
Man is but a worm: Chordate origins
Brown FD, Prendergast A, Swalla BJ. Man is but a worm: Chordate origins. Genesis 2008, 46: 605-613. PMID: 19003926, DOI: 10.1002/dvg.20471.Peer-Reviewed Original ResearchConceptsDevelopmental gene expression dataHox gene clustersSimilar gene familiesDevelopmental gene expressionOrigin of chordatesDorsal-ventral patterningPharyngeal gill slitsUnique body planExpression of BMPAnterior-posterior axisOrigin of SpeciesDorsal-ventral axisGene expression dataChordate ancestorDeuterostome ancestorChordate originsLeft-right asymmetryGene familyBody planDeuterostome phylaGene clusterMolecular dataTranscription factorsChordatesPharyngeal slits