Amy Bei, PhD
Associate Professor of Epidemiology (Mircrobial Diseases)DownloadHi-Res Photo
Cards
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
About
Copy Link
Titles
Associate Professor of Epidemiology (Mircrobial Diseases)
Affiliated Faculty, Yale Institute for Global Health
Biography
Dr. Bei’s research interests in Plasmodium – the causative agent of malaria - lie at the intersection between population genetics, genomics, molecular genetics, epidemiology, and immunology. Her current research uses a translational systems biology approach to study the impact of antigenic diversity on immune evasion, transmission, and virulence in setting of declining malaria transmission. She is studying the development of genotype-specific and genotype-transcendent immunity and assess the effect of specific persisting genotypes on neutralizing humoral immune responses and their transmission potential in the mosquito vector. She also works on malaria vaccine candidate discovery and validation, studying the functional consequences of naturally arising diversity. Dr. Bei has ongoing research projects in Senegal in addition to many active collaborations in Sub-Saharan African countries in both East and West Africa.
Last Updated on April 07, 2025.
Appointments
Epidemiology of Microbial Diseases
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral Fellow
- Harvard TH Chan School of Public Health/Hospital Aristide Le Dantec, Dakar, Senegal (2018)
- PhD
- Harvard University, Biological Sciences in Public Health
- Fulbright Fellow
- Muhimbili University College of Health Sciences (2004)
- BA
- Harvard College, Biochemistry (2003)
Research
Copy Link
Overview
Medical Research Interests
Adaptive Immunity; Africa; Biostatistics; Disease Transmission, Infectious; Ecology; Genetics; Genetics, Population; Genomics; Host-Pathogen Interactions; Malaria Vaccines; Malaria, Falciparum; Molecular Epidemiology; Senegal
Public Health Interests
Genetics, Genomics, Epigenetics; Global Health; Infectious Diseases
ORCID
0000-0003-1159-760X- View Lab Website
Bei Lab
Research at a Glance
Yale Co-Authors
Frequent collaborators of Amy Bei's published research.
Publications Timeline
A big-picture view of Amy Bei's research output by year.
Research Interests
Research topics Amy Bei is interested in exploring.
Sunil Parikh, MD, MPH
Albert Icksang Ko, MD
Jean Bosco Ouedraogo
Morgan Goheen, MD, PhD
Anne Wyllie
Former YSMChikondi Peno
Former YSM
50Publications
2,038Citations
Malaria, Falciparum
Senegal
Malaria Vaccines
Host-Pathogen Interactions
Genetics, Population
Publications
2026
Anopheles Mosquitoes Exposed to Long-Acting Antimalarials via Drug-Supplemented Bloodmeal Absorb Drug but Do Not Suffer Fitness Costs
Goheen M, Orfanó A, Dah S, Foy B, Brackney D, Li F, Ouédraogo J, Da D, Dabiré R, Somé A, Bei A, Parikh S. Anopheles Mosquitoes Exposed to Long-Acting Antimalarials via Drug-Supplemented Bloodmeal Absorb Drug but Do Not Suffer Fitness Costs. Journal Of Infectious Diseases 2026, jiag300. PMID: 42296192, DOI: 10.1093/infdis/jiag300.Peer-Reviewed Original ResearchCitationsAltmetricGenetic diversity of the malaria vaccine candidate PfRIPR in a high transmission region of Senegal
Nair M, Geering G, Agarwal A, Li R, Qiao Y, Xiao Q, Pouye M, Thiam L, Ba A, Hagadorn K, Cisse A, Guerra N, Tawaldemedhen Y, Mangou K, Moore A, Diallo F, Sene S, Sadio B, Zhang E, Shapiro L, Patel S, Mbengue A, Vigan-Womas I, Sheng Z, Bei A. Genetic diversity of the malaria vaccine candidate PfRIPR in a high transmission region of Senegal. IScience 2026, 29: 114883. PMID: 41736865, PMCID: PMC12927061, DOI: 10.1016/j.isci.2026.114883.Peer-Reviewed Original ResearchCitationsGenetic diversity in the Plasmodium falciparum next-generation blood stage vaccine candidate antigen PfCyRPA in Senegal
Ba A, Thiam L, Pouye M, Guo Y, Patel S, Sene S, Diallo F, Li R, Cisse A, Guerra N, Laqqa S, Mangou K, Moore A, Sadio B, Ndiaye J, Mbengue A, Vigan-Womas I, Sheng Z, Shapiro L, Bei A. Genetic diversity in the Plasmodium falciparum next-generation blood stage vaccine candidate antigen PfCyRPA in Senegal. Scientific Reports 2026, 16: 5661. PMID: 41549078, PMCID: PMC12891623, DOI: 10.1038/s41598-026-36257-z.Peer-Reviewed Original ResearchCitations
2025
Household practices and infrastructure associated with high Plasmodium falciparum infection rates among children under five years old in Northern Uganda
Echodu R, Ajolorwot S, Aryemo F, Nyeko C, Okot J, Iwiru T, Nakiwu V, Bei A, DeBlasio M, Turyasingura N, Zhang E, Parikh S. Household practices and infrastructure associated with high Plasmodium falciparum infection rates among children under five years old in Northern Uganda. Malaria Journal 2025, 24: 181. PMID: 40484941, PMCID: PMC12145591, DOI: 10.1186/s12936-025-05288-8.Peer-Reviewed Original ResearchMonitoring molecular markers associated with antimalarial drug resistance in south-east Senegal from 2021 to 2023
Wade A, Sene S, Caspar E, Diallo F, Platon L, Thiebaut L, Pouye M, Ba A, Thiam L, Fall M, Sadio B, Desamours I, Guerra N, Hagadorn K, Amambua-Ngwa A, Bei A, Vigan-Womas I, Ménard D, Mbengue A. Monitoring molecular markers associated with antimalarial drug resistance in south-east Senegal from 2021 to 2023. Journal Of Antimicrobial Chemotherapy 2025, 80: 828-839. PMID: 39846779, PMCID: PMC11879165, DOI: 10.1093/jac/dkaf006.Peer-Reviewed Original ResearchCitationsMeSH KeywordsAdolescentAdultAntimalarialsArtemisininsChildChild, PreschoolDrug CombinationsDrug ResistanceFemaleHumansMalaria, FalciparumMaleMembrane Transport ProteinsMiddle AgedMultidrug Resistance-Associated ProteinsMutationPlasmodium falciparumProtozoan ProteinsPyrimethamineSenegalSulfadoxineTetrahydrofolate DehydrogenaseYoung Adult
2024
Two Mosquito Salivary Antigens Demonstrate Promise as Biomarkers of Recent Exposure to Plasmodium falciparum–Infected Mosquito Bites
Lapidus S, Goheen M, Sy M, Deme A, Ndiaye I, Diedhiou Y, Mbaye A, Hagadorn K, Sene S, Pouye M, Thiam L, Ba A, Guerra N, Mbengue A, Raduwan H, Gagnon J, Vigan-Womas I, Parikh S, Ko A, Ndiaye D, Fikrig E, Chuang Y, Bei A. Two Mosquito Salivary Antigens Demonstrate Promise as Biomarkers of Recent Exposure to Plasmodium falciparum–Infected Mosquito Bites. Journal Of Infectious Diseases 2024, 231: e570-e581. PMID: 39475423, PMCID: PMC11911913, DOI: 10.1093/infdis/jiae525.Peer-Reviewed Original ResearchCitationsVaccine-induced human monoclonal antibodies to PfRH5 show broadly neutralizing activity against P. falciparum clinical isolates
Thiam L, McHugh K, Ba A, Li R, Guo Y, Pouye M, Cisse A, Pipini D, Diallo F, Sene S, Patel S, Thiam A, Sadio B, Mbengue A, Vigan-Womas I, Sheng Z, Shapiro L, Draper S, Bei A. Vaccine-induced human monoclonal antibodies to PfRH5 show broadly neutralizing activity against P. falciparum clinical isolates. Npj Vaccines 2024, 9: 198. PMID: 39448626, PMCID: PMC11502735, DOI: 10.1038/s41541-024-00986-x.Peer-Reviewed Original ResearchCitationsAltmetricA kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria
Chahine Z, Abel S, Hollin T, Barnes G, Chung J, Daub M, Renard I, Choi J, Vydyam P, Pal A, Alba-Argomaniz M, Banks C, Kirkwood J, Saraf A, Camino I, Castaneda P, Cuevas M, De Mercado-Arnanz J, Fernandez-Alvaro E, Garcia-Perez A, Ibarz N, Viera-Morilla S, Prudhomme J, Joyner C, Bei A, Florens L, Mamoun C, Vanderwal C, Le Roch K. A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria. Science 2024, 385: eadm7966-eadm7966. PMID: 39325875, PMCID: PMC11793105, DOI: 10.1126/science.adm7966.Peer-Reviewed Original ResearchCitationsAltmetricUnderstanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory
Nahid D, Coffey K, Bei A, Cordy R. Understanding the significance of oxygen tension on the biology of Plasmodium falciparum blood stages: From the human body to the laboratory. PLOS Pathogens 2024, 20: e1012514. PMID: 39298535, PMCID: PMC11412506, DOI: 10.1371/journal.ppat.1012514.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricImproved species assignments across the entire Anopheles genus using targeted sequencing
Boddé M, Makunin A, Teltscher F, Akorli J, Andoh N, Bei A, Chaumeau V, Desamours I, Ekpo U, Govella N, Kayondo J, Kobylinski K, Ngom E, Niang E, Okumu F, Omitola O, Ponlawat A, Rakotomanga M, Rasolonjatovoniaina M, Ayala D, Lawniczak M. Improved species assignments across the entire Anopheles genus using targeted sequencing. Frontiers In Genetics 2024, 15: 1456644. PMID: 39364005, PMCID: PMC11446804, DOI: 10.3389/fgene.2024.1456644.Peer-Reviewed Original ResearchCitations
News
Copy Link
News
- July 08, 2026
Bei Wins Fulbright for Malaria Vaccinology Program in Senegal
- January 12, 2026
Meeting Malaria Where It Lives
- December 01, 2025Source: CT Mirror
Philanthropic funding helps YSPH professor continue important malaria research
- November 21, 2025
World Antimicrobial Resistance Awareness Week 2025
Get In Touch
Copy Link
Contacts
Email