2004
Randomized trial of Rotational Atherectomy Versus Balloon Angioplasty for Diffuse In-stent Restenosis (ROSTER)
Sharma SK, Kini A, Mehran R, Lansky A, Kobayashi Y, Marmur JD. Randomized trial of Rotational Atherectomy Versus Balloon Angioplasty for Diffuse In-stent Restenosis (ROSTER). American Heart Journal 2004, 147: 16-22. PMID: 14691413, DOI: 10.1016/j.ahj.2003.07.002.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationPrimary end pointDiffuse ISRPTCA groupBalloon angioplastyBalloon dilatationStent restenosisCoronary artery bypass graft proceduresIn-Stent Restenosis TrialStudy's primary end pointEnd pointHigh-pressure balloon dilatationRotational coronary atherectomySecondary end pointsBypass graft proceduresIntravascular ultrasound studyAcute luminal gainAdjunctive balloon dilatationIntimal hyperplasia areaAngiographic substudyAngiographic variablesLesion revascularizationRepeat stentingAngiographic restenosisAngiographic success
2003
Benefits of cutting balloon before stenting.
Rizik DG, Popma JP, Leon MB, Mintz GS, Weiner B, Cohen E, Lansky AJ, Adem AM, Bouhasin AP, Wojciechowski C, Weissman NJ. Benefits of cutting balloon before stenting. Journal Of Invasive Cardiology 2003, 15: 624-8. PMID: 14608131.Peer-Reviewed Original ResearchConceptsMinimal stent cross-sectional areaStent cross-sectional areaStent implantationIntravascular ultrasoundCross-sectional areaCulprit coronary artery lesionStent percent diameter stenosisDe novo coronary lesionsSignificant coronary artery diseaseHospital complication ratesNovo coronary lesionsCoronary artery lesionsCoronary artery diseaseCoronary stent implantationAcute luminal gainPercent diameter stenosisQuantitative coronary angiographyArtery lesionsCulprit lesionStent restenosesArtery diseaseComplication rateCoronary angiographyCoronary lesionsBalloon angioplastySafety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study
Stone GW, Cox DA, Low R, Cates CU, Satler L, Bailey SR, Kuntz RE, Lansky AJ. Safety and efficacy of a novel device for treatment of thrombotic and atherosclerotic lesions in native coronary arteries and saphenous vein grafts: Results from the multicenter X‐sizer for treatment of thrombus and atherosclerosis in coronary applications trial (X‐TRACT) study. Catheterization And Cardiovascular Interventions 2003, 58: 419-427. PMID: 12652487, DOI: 10.1002/ccd.10511.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAtherectomy, CoronaryChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary ThrombosisEquipment DesignEquipment SafetyFemaleFollow-Up StudiesGraft Occlusion, VascularHumansMaleMiddle AgedProbabilityRisk AssessmentSaphenous VeinStatistics, NonparametricStentsThrombectomyTreatment OutcomeConceptsSaphenous vein graftsNative coronary arteriesVein graftsX-SizerThrombotic lesionsCoronary arteryNon-Q-wave MIDistal branch occlusionTIMI 3 flowSide branch occlusionTreatment of thrombusDistal thromboemboliPeriprocedural MITIMI 0Adverse eventsThromboembolic complicationsConsecutive patientsAntegrade flowBranch occlusionPercutaneous interventionHistorical controlsAtherosclerotic lesionsTrial studyU.S. CentersLesions
2001
Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure
Gruberg L, Dangas G, Mehran R, Mintz GS, Kent KM, Pichard AD, Satler LF, Lansky AJ, Stone GW, Leon MB. Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure. Catheterization And Cardiovascular Interventions 2001, 55: 66-72. PMID: 11793497, DOI: 10.1002/ccd.10103.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseChronic renal failurePercutaneous coronary interventionClinical outcomesLate mortalityRenal dysfunctionCoronary interventionRenal failureRenal functionRenal diseaseHigher left ventricular ejection fractionNon-Q-wave myocardial infarctionLeft ventricular ejection fractionAngiographic success rateImpaired renal functionNormal renal functionVentricular ejection fractionHospital mortalityCreatinine clearanceConsecutive patientsDiabetes mellitusEjection fractionIndependent correlatesMyocardial infarctionLarge cohortEffect of gender on the outcomes of contemporary percutaneous coronary intervention
Peterson E, Lansky A, Kramer J, Anstrom K, Lanzilotta M, Investigators F. Effect of gender on the outcomes of contemporary percutaneous coronary intervention. The American Journal Of Cardiology 2001, 88: 359-364. PMID: 11545754, DOI: 10.1016/s0002-9149(01)01679-4.Peer-Reviewed Original ResearchConceptsIndependent risk factorRisk factorsBaseline clinical risk factorsHigher vascular complication ratesContemporary percutaneous coronary interventionPercutaneous coronary intervention (PCI) technologyRisk adjustmentExtensive coronary diseaseProcedural mortality rateVascular complication ratesClinical risk factorsPercutaneous coronary interventionBody surface areaPatient body sizeHospital revascularizationAssociation of genderComorbid illnessesVascular complicationsComplication rateCoronary interventionCoronary diseaseProcedural outcomesFemale genderIndependent riskPCI cases
2000
Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy
Mehran R, Dangas G, Mintz G, Waksman R, Abizaid A, Satler L, Pichard A, Kent K, Lansky A, Stone G, Leon M. Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy. Circulation 2000, 101: 2484-2489. PMID: 10831522, DOI: 10.1161/01.cir.101.21.2484.Peer-Reviewed Original ResearchConceptsExcimer laser coronary angioplastyVolumetric IVUS analysisRotational atherectomyQuantitative coronary angiographicClinical resultsCoronary angiographicIVUS analysisLumen enlargementSimilar long-term clinical outcomesTarget lesion revascularization rateLong-term clinical outcomesSignificant between-group differencesIntimal hyperplasia volumeLesion revascularization rateLaser coronary angioplastyTreatment of diffuseIn-Stent RestenosisSimilar clinical resultsBetween-group differencesIntravascular ultrasound measurementsAdjunct PTCADiffuse ISRHospital complicationsAngiographic successRevascularization ratesComparison of debulking followed by stenting versus stenting alone for saphenous vein graft aortoostial lesions: immediate and one-year clinical outcomes
Ahmed J, Hong M, Mehran R, Mintz G, Lansky A, Pichard A, Satler L, Kent K, Wu H, Stone G, Leon M. Comparison of debulking followed by stenting versus stenting alone for saphenous vein graft aortoostial lesions: immediate and one-year clinical outcomes. Journal Of The American College Of Cardiology 2000, 35: 1560-1568. PMID: 10807461, DOI: 10.1016/s0735-1097(00)00592-1.Peer-Reviewed Original ResearchConceptsOne-year clinical outcomesLumen cross-sectional areaLate clinical outcomesClinical outcomesStent implantationProcedural successRestenotic lesionsIntravascular ultrasoundCross-sectional areaOverall cardiac event-free survivalCardiac event-free survivalLate cardiac eventsEvent-free survivalOverall procedural successCox regression analysisComplex lesion subsetsPalmaz-Schatz stentsLesion revascularizationCardiac eventsMost patientsConsecutive patientsIndependent predictorsProcedural complicationsLesion subsetsMyocardial infarctionPrognostic value of cardiac troponin-I levels following catheter-based coronary interventions
Fuchs S, Kornowski R, Mehran R, Lansky A, Satler L, Pichard A, Kent K, Clark C, Stone G, Leon M. Prognostic value of cardiac troponin-I levels following catheter-based coronary interventions. The American Journal Of Cardiology 2000, 85: 1077-1082. PMID: 10781755, DOI: 10.1016/s0002-9149(00)00699-8.Peer-Reviewed Original ResearchConceptsCatheter-based coronary interventionsCK-MB levelsHospital complicationsCoronary interventionCreatine kinase-MB fraction levelsCardiac event-free survivalIntermediate-term clinical outcomesTn-I levelsEvent-free survivalIntermediate-term outcomesRisk of mortalityQ-wave infarctionLesion revascularizationConsecutive patientsCoronary angioplastyIndependent predictorsClinical outcomesPrognostic significancePrognostic valueCoronary arteryMyocardial infarctionPlasma levelsSaphenous veinNormal limitsGroup IIEvolving trends in interventional device use and outcomes: Results from the National Cardiovascular Network database
Peterson E, Lansky A, Anstrom K, Muhlbaier L, Popma J, Satler L, Lanzilotta M, Network F. Evolving trends in interventional device use and outcomes: Results from the National Cardiovascular Network database. American Heart Journal 2000, 139: 198-207. PMID: 10650291, DOI: 10.1016/s0002-8703(00)90226-6.Peer-Reviewed Original ResearchConceptsComplication rateCoronary anatomyAtherectomy devicesInterventional strategiesClinical practiceNew coronary interventional devicesCoronary stentsCoronary interventional devicesCoronary stent usePatient's coronary anatomyPercutaneous interventional strategyPostprocedure hospital stayProcedural success rateOverall mortality rateGeneral clinical practiceNew interventional strategiesDevice usePercentage of casesRotational atherectomy deviceInterventional databasePostprocedure lengthHospital stayCoronary interventionDirectional atherectomyPatient characteristicsEffect of plaque debulking and stenting on short- and long-term outcomes after revascularization of chronic total occlusions
Gruberg L, Mehran R, Dangas G, Hong M, Mintz G, Kornowski R, Lansky A, Kent K, Pichard A, Satler L, Stone G, Leon M. Effect of plaque debulking and stenting on short- and long-term outcomes after revascularization of chronic total occlusions. Journal Of The American College Of Cardiology 2000, 35: 151-156. PMID: 10636273, DOI: 10.1016/s0735-1097(99)00491-x.Peer-Reviewed Original ResearchConceptsLesion revascularization rateChronic total occlusionRevascularization ratesClinical outcomesTotal occlusionCoronary arteryStent deploymentTarget lesion revascularization rateLong-term clinical outcomesCoronary artery locationLate clinical outcomesPrimary success rateNative coronary arteriesGroup of patientsCoronary artery occlusionLong-term outcomesSuccessful stent deploymentNew interventional devicesEffect of plaqueAngioplasty ratesHospital mortalityLesion modificationSuccessful stentingAngiographic characteristicsHospital outcomes
1999
Comparative analysis of early and late angiographic outcomes using two quantitative algorithms in the Balloon versus Optimal Atherectomy Trial (BOAT)
Lansky A, Popma J, Cutlip D, Ho K, Abizaid A, Saucedo J, Zhang Y, Senerchia C, Kuntz R, Leon M, Baim D, Investigators F. Comparative analysis of early and late angiographic outcomes using two quantitative algorithms in the Balloon versus Optimal Atherectomy Trial (BOAT). The American Journal Of Cardiology 1999, 83: 1611-1616. PMID: 10392863, DOI: 10.1016/s0002-9149(99)00166-6.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAngioplasty, Balloon, CoronaryAtherectomy, CoronaryCineangiographyCoronary AngiographyHumansRadiographic Image EnhancementTime FactorsConceptsMinimal lumen diameterPercent diameter stenosisBaseline minimal lumen diameterDiameter stenosisReference diameterDirectional atherectomyBaseline measurementsBaseline reference diameterQuantitative angiographic analysisLate angiographic outcomeAngiographic findingsAngiographic outcomesRestenosis rateBalloon angioplastyAngiographic analysisTreatment benefitTreatment groupsAngiographic laboratoryLumen diameterStenosisIndependent observersLesion irregularityAtherectomyPatientsTrials
1998
Remodeling after directional coronary atherectomy (with and without adjunct percutaneous transluminal coronary angioplasty): a serial angiographic and intravascular ultrasound analysis from the optimal atherectomy restenosis study
Lansky A, Mintz G, Popma J, Pichard A, Kent K, Satler L, Baim D, Kuntz R, Simonton C, Bersin R, Hinohara T, Fitzgerald P, Leon M. Remodeling after directional coronary atherectomy (with and without adjunct percutaneous transluminal coronary angioplasty): a serial angiographic and intravascular ultrasound analysis from the optimal atherectomy restenosis study. Journal Of The American College Of Cardiology 1998, 32: 329-337. PMID: 9708457, DOI: 10.1016/s0735-1097(98)00245-9.Peer-Reviewed Original ResearchMeSH KeywordsAnatomy, Cross-SectionalAngioplasty, Balloon, CoronaryAtherectomy, CoronaryCell DivisionCerebral AngiographyCineradiographyCombined Modality TherapyConstriction, PathologicCoronary Artery DiseaseCoronary VesselsElastic TissueFemaleFollow-Up StudiesHumansMaleMiddle AgedNitroglycerinRecurrenceTunica MediaUltrasonography, InterventionalVasodilator AgentsConceptsDirectional coronary atherectomyExternal elastic membraneMinimum lumen diameterLumen cross-sectional areaQuantitative coronary angiographyDiameter stenosisCoronary atherectomyCross-sectional areaReference segmentsLesion external elastic membraneOptimal directional coronary atherectomyEEM cross-sectional areaIntravascular ultrasound substudySerial IVUS studyIntravascular ultrasound analysisMajor side branchesMechanism of restenosisIntravascular ultrasound measurementsUltrasound substudyIntracoronary nitroglycerinCoronary angiographyRestenotic lesionsLate lumenArterial remodelingIVUS studyFinal Results of the Balloon vs Optimal Atherectomy Trial (BOAT)
Baim D, Cutlip D, Sharma S, Ho K, Fortuna R, Schreiber T, Feldman R, Shani J, Senerchia C, Zhang Y, Lansky A, Popma J, Kuntz R. Final Results of the Balloon vs Optimal Atherectomy Trial (BOAT). Circulation 1998, 97: 322-331. PMID: 9468205, DOI: 10.1161/01.cir.97.4.322.Peer-Reviewed Original ResearchConceptsAngiographic restenosisBalloon angioplastyHigh short-term successPrespecified primary end pointLower angiographic restenosisNative vessel lesionsSingle de novoPrimary end pointTarget vessel failureTarget vessel revascularizationResidual diameter stenosisLate clinical eventsConventional balloon angioplastyCreatine kinase-MBLow residual stenosisSignificant reductionHospital complicationsResidual stenosisLesion successMajor complicationsAngiographic restudyDiameter stenosisVessel lesionsClinical eventsLong-term benefits