2022
Intravascular Imaging for Guiding In‐Stent Restenosis and Stent Thrombosis Therapy
Erdogan E, Bajaj R, Lansky A, Mathur A, Baumbach A, Bourantas C. Intravascular Imaging for Guiding In‐Stent Restenosis and Stent Thrombosis Therapy. Journal Of The American Heart Association 2022, 11: e026492. PMID: 36326067, PMCID: PMC9750080, DOI: 10.1161/jaha.122.026492.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionCoronary interventionStent failureStent restenosisStent thrombosisSecond-generation drug-eluting stentsConventional percutaneous coronary interventionHigh-risk patientsBetter clinical outcomesLong-term outcomesDrug-eluting stentsCumulative incidenceClinical outcomesWorse prognosisProcedural resultsComplex anatomyEndovascular devicesRestenosisTherapyStent technologyDrug kineticsIntravascular imagingTreatment planningNeointima tissueThrombosisPercutaneous Coronary Intervention vs. Coronary Artery Bypass Grafting for Treating In-Stent Restenosis in Unprotected-Left Main: LM-DRAGON-Registry
Wańha W, Bil J, Kołodziejczak M, Kowalówka A, Kowalewski M, Hudziak D, Gocoł R, Januszek R, Figatowski T, Milewski M, Tomasiewicz B, Kübler P, Hrymniak B, Desperak P, Kuźma Ł, Milewski K, Góra B, Łoś A, Kulczycki J, Włodarczak A, Skorupski W, Grygier M, Lesiak M, D'Ascenzo F, Andres M, Kleczynski P, Litwinowicz R, Borin A, Smolka G, Reczuch K, Gruchała M, Gil RJ, Jaguszewski M, Bartuś K, Suwalski P, Dobrzycki S, Dudek D, Bartuś S, Ga̧sior M, Ochała A, Lansky AJ, Deja M, Legutko J, Kedhi E, Wojakowski W. Percutaneous Coronary Intervention vs. Coronary Artery Bypass Grafting for Treating In-Stent Restenosis in Unprotected-Left Main: LM-DRAGON-Registry. Frontiers In Cardiovascular Medicine 2022, 9: 849971. PMID: 35615559, PMCID: PMC9125786, DOI: 10.3389/fcvm.2022.849971.Peer-Reviewed Original ResearchPercutaneous coronary interventionTarget vessel revascularizationCoronary artery bypassCardiac deathMyocardial infarctionPCI groupArtery bypassCoronary interventionStent restenosisUnprotected left main coronary arteryLeft main coronary arteryMain coronary arteryManagement of patientsAnalysis of patientsCerebrovascular eventsPrimary endpointVessel revascularizationConsecutive patientsCoronary arteryCABGLower incidenceLower riskPatientsDeathMACCE
2021
TCT-101 Long-Term Outcomes Following Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Treating In-Stent Restenosis in Unprotected Left Main Coronary Artery: Multicenter LM-DRAGON Registry
Wańha W, Bil J, Kołodziejczak M, Kowalowka A, Hudziak D, Gocol R, Kowalewski M, Januszek R, Figatowski T, Milewski M, Tomasiewicz B, Kubler P, Desperak P, Kuźma Ł, Milewski K, Gora B, Los A, Kulczycki J, Wlodarczak A, Grygier M, Lesiak M, Kleczynski P, Litwinowicz R, Borin A, Smolka G, Reczuch K, Gruchała M, Gil R, Jaguszewski M, Bartus K, Suwalski P, Dobrzycki S, Dudek D, Bartus S, Gasior M, Legutko J, Ochała A, Lansky A, Deja M, Kedhi E, Wojakowski W. TCT-101 Long-Term Outcomes Following Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Treating In-Stent Restenosis in Unprotected Left Main Coronary Artery: Multicenter LM-DRAGON Registry. Journal Of The American College Of Cardiology 2021, 78: b42-b43. DOI: 10.1016/j.jacc.2021.09.951.Peer-Reviewed Original Research
2020
Survival After Coronary Revascularization With Paclitaxel-Coated Balloons
Scheller B, Vukadinovic D, Jeger R, Rissanen TT, Scholz SS, Byrne R, Kleber FX, Latib A, Clever YP, Ewen S, Böhm M, Yang Y, Lansky A, Mahfoud F. Survival After Coronary Revascularization With Paclitaxel-Coated Balloons. Journal Of The American College Of Cardiology 2020, 75: 1017-1028. PMID: 32138961, DOI: 10.1016/j.jacc.2019.11.065.Peer-Reviewed Original ResearchConceptsDrug-coated balloonsPaclitaxel-coated balloonRisk of deathCause mortalityRisk ratioStent restenosisPaclitaxel drug-coated balloonPaclitaxel-coated devicesDe novo lesionsCoronary artery diseaseSuperficial femoral arteryCochrane Library databasesConfidence intervalsNumber of patientsWeb of ScienceCardiac mortalityCoronary revascularizationNovo lesionsCoronary interventionDCB groupDifferent time pointsArtery diseasePrimary outcomeFemoral arteryPeripheral arteries
2013
Drug eluting balloons for de novocoronary lesions – a systematic review and meta-analysis
Fröhlich GM, Lansky AJ, Ko DT, Archangelidi O, De Palma R, Timmis A, Meier P. Drug eluting balloons for de novocoronary lesions – a systematic review and meta-analysis. BMC Medicine 2013, 11: 123. PMID: 23657123, PMCID: PMC3648374, DOI: 10.1186/1741-7015-11-123.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsNovo coronary lesionsTarget lesion revascularizationBare metal stentsLate lumen lossDrug-eluting balloonsDe novo coronary lesionsCurrent standard therapyDrug-Eluting BalloonRelative riskCoronary lesionsStent thrombosisMyocardial infarctionStandard therapyStent restenosisSystematic reviewLower late lumen lossAdverse cardiac eventsPooled relative riskRandom-effects modelLesion revascularizationSegment restenosisCardiac eventsComparator treatmentResultsEight studiesDrug-eluting balloon angioplasty for in-stent restenosis: a systematic review and meta-analysis of randomised controlled trials
Indermuehle A, Bahl R, Lansky AJ, Froehlich GM, Knapp G, Timmis A, Meier P. Drug-eluting balloon angioplasty for in-stent restenosis: a systematic review and meta-analysis of randomised controlled trials. Heart 2013, 99: 327. PMID: 23335497, DOI: 10.1136/heartjnl-2012-302945.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsDrug-eluting balloonsDrug-eluting balloon angioplastyBalloon angioplastyStent restenosisStent thrombosisMyocardial infarctionRelative riskSegment restenosisTreatment optionsSystematic reviewIncidence of MIRisk of STAdverse cardiac eventsPooled relative riskPlain balloon angioplastyOptimal treatment optionsPromising treatment optionDrug-eluting stentsRandom-effects modelLesion revascularisationCardiac eventsCoronary angioplastyMain endpointClinical trials
2010
Serial Intravascular Ultrasound Analysis of the Impact of Myocardial Bridge on Neointimal Proliferation After Coronary Stenting in Patients with Acute Myocardial Infarction
TSUJITA K, MAEHARA A, MINTZ GS, LANSKY AJ, KUBO T, DOI H, YANG J, BHARAJ H, WITZENBICHLER B, GUAGLIUMI G, BRODIE BR, KELLETT MA, PARISE H, MEHRAN R, STONE GW. Serial Intravascular Ultrasound Analysis of the Impact of Myocardial Bridge on Neointimal Proliferation After Coronary Stenting in Patients with Acute Myocardial Infarction. Journal Of Interventional Cardiology 2010, 23: 114-122. PMID: 20236216, DOI: 10.1111/j.1540-8183.2010.00531.x.Peer-Reviewed Original ResearchConceptsCulprit lesionIntimal hyperplasiaIntravascular ultrasoundStent groupMyocardial bridgeLAD stentAcute Myocardial Infarction trialLumen areaSerial intravascular ultrasound analysisMyocardial Infarction trialAcute myocardial infarctionStent recoilSerial intravascular ultrasoundIncidence of ISRIntravascular ultrasound analysisMinimum lumen areaHarmonizing OutcomesCoronary stentingMyocardial infarctionNeointimal proliferationStent restenosisUltrasound analysisStent segmentMb segmentPatients
2009
A Volumetric Intravascular Ultrasound Comparison of Early Drug-Eluting Stent Thrombosis Versus Restenosis
Liu X, Doi H, Maehara A, Mintz GS, de Ribamar Costa J, Sano K, Weisz G, Dangas GD, Lansky AJ, Kreps EM, Collins M, Fahy M, Stone GW, Moses JW, Leon MB, Mehran R. A Volumetric Intravascular Ultrasound Comparison of Early Drug-Eluting Stent Thrombosis Versus Restenosis. JACC Cardiovascular Interventions 2009, 2: 428-434. PMID: 19463466, DOI: 10.1016/j.jcin.2009.01.011.Peer-Reviewed Original ResearchConceptsStent thrombosis groupIntravascular ultrasound findingsMinimum stent areaStent areaThrombosis groupISR groupStent thrombosisUltrasound findingsIntravascular Ultrasound ComparisonProximal stent segmentISR patientsDES thrombosisEdge dissectionStent underexpansionUltrasound comparisonStent fractureThrombosis patientsEarlier drugsStent restenosisThrombosisPatientsStent expansionStent segmentRestenosisLesionsImpact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement
Tsujita K, Maehara A, Mintz GS, Doi H, Kubo T, Castellanos C, Liu J, Yang J, Oviedo C, Franklin-Bond T, Sugirtharaj DD, Dangas GD, Lansky AJ, Stone GW, Moses JW, Leon MB, Mehran R. Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement. The American Journal Of Cardiology 2009, 103: 1344-1348. PMID: 19427426, DOI: 10.1016/j.amjcard.2009.01.340.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationCoronary stent placementStent placementMyocardial bridgeArtery lesionsObstructive lesionsClinical outcomesStent groupTarget lesion revascularization rateStent group patientsTarget vessel revascularizationComposite end pointCoronary artery lesionsMinimum stent areaGroup patientsRevascularization ratesConsecutive patientsLeft anteriorObstructive diseaseSystolic compressionCoronary arterySignificant plaqueStent areaStent restenosisIntravascular ultrasound
2008
Angiographic Patterns of Drug-Eluting Stent Restenosis and One-Year Outcomes After Treatment With Repeated Percutaneous Coronary Intervention
Solinas E, Dangas G, Kirtane AJ, Lansky AJ, Franklin-Bond T, Boland P, Syros G, Kim YH, Gupta A, Mintz G, Fahy M, Collins M, Kodali S, Stone GW, Moses JW, Leon MB, Mehran R. Angiographic Patterns of Drug-Eluting Stent Restenosis and One-Year Outcomes After Treatment With Repeated Percutaneous Coronary Intervention. The American Journal Of Cardiology 2008, 102: 311-315. PMID: 18638592, DOI: 10.1016/j.amjcard.2008.03.060.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionMajor adverse cardiac eventsPatterns of ISRAdverse cardiac eventsTarget lesion revascularizationDES-ISRCoronary interventionPES-ISRCardiac eventsBalloon angioplastyStent restenosisDrug-eluting stent implantationColumbia University Medical CenterDES-ISR lesionsOne-year outcomesPaclitaxel-eluting stentsUnselected patient populationSirolimus-eluting stentsUniversity Medical CenterLow overall rateAngiographic patternsDES implantationDES placementISR lesionsConsecutive patients
2007
Clinical Outcomes After Heterogeneous Overlap Stenting With Drug-Eluting Stents and Bare-Metal Stents for de Novo Coronary Artery Narrowings
Aoki J, Kirtane AJ, Dangas GD, Lansky AJ, Morales A, Kimura M, Kim YH, Moussa I, Weisz G, Kreps EM, Collins M, Frankin-Bond T, Stone GW, Moses JW, Leon MB, Mehran R. Clinical Outcomes After Heterogeneous Overlap Stenting With Drug-Eluting Stents and Bare-Metal Stents for de Novo Coronary Artery Narrowings. The American Journal Of Cardiology 2007, 101: 58-62. PMID: 18157966, DOI: 10.1016/j.amjcard.2007.07.049.Peer-Reviewed Original ResearchConceptsDrug-eluting stentsBare metal stentsClinical outcomesTarget vessel revascularization rateMultiple drug-eluting stentsAcute stent thrombosisVessel revascularization rateDe novo lesionsTarget vessel revascularizationPercutaneous coronary interventionCoronary artery narrowingImplanted stent diameterNovo lesionsProspective registryRevascularization ratesVessel revascularizationBMS implantationCoronary interventionDES implantationConsecutive patientsArtery narrowingStent thrombosisMyocardial infarctionStent restenosisStent diameter
2006
Volumetric Intravascular Ultrasound Assessment of Neointimal Hyperplasia and Nonuniform Stent Strut Distribution in Sirolimus-Eluting Stent Restenosis
Sano K, Mintz GS, Carlier SG, Fujii K, Takebayashi H, Kimura M, Costa JR, Tanaka K, Costa RA, Lui J, Weisz G, Moussa I, Dangas GD, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Volumetric Intravascular Ultrasound Assessment of Neointimal Hyperplasia and Nonuniform Stent Strut Distribution in Sirolimus-Eluting Stent Restenosis. The American Journal Of Cardiology 2006, 98: 1559-1562. PMID: 17145209, DOI: 10.1016/j.amjcard.2006.07.030.Peer-Reviewed Original ResearchConceptsMinimum lumen siteStent restenotic lesionsStent areaDiabetes mellitusLumen areaRestenotic lesionsStent strut distributionIH areaMinimal lumen area siteSirolimus-eluting stent implantationVolumetric intravascular ultrasound analysisIntravascular ultrasound assessmentMinimum stent areaIntravascular ultrasound analysisMinimum lumen areaMinimal lumen areaMinimal lumen siteIH responseSES implantationStent implantationUltrasound assessmentStent lengthNeointimal hyperplasiaStent restenosisStrut distributionPredictors of Recurrent In‐Stent Restenosis after Beta‐Radiation: An Analysis from the START 40/20 Trial
KANEDA H, HONDA Y, MORINO Y, LANSKY AJ, YOCK PG, BONAN R, FITZGERALD PJ. Predictors of Recurrent In‐Stent Restenosis after Beta‐Radiation: An Analysis from the START 40/20 Trial. Journal Of Interventional Cardiology 2006, 19: 376-380. PMID: 17020560, DOI: 10.1111/j.1540-8183.2006.00188.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAnalysis of VarianceAngioplasty, Balloon, CoronaryBeta ParticlesBlood Vessel Prosthesis ImplantationBrachytherapyCoronary AngiographyCoronary Artery BypassCoronary RestenosisFemaleFollow-Up StudiesHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesRadiopharmaceuticalsRecurrenceStentsStrontium RadioisotopesTreatment OutcomeUltrasonography, InterventionalYttrium RadioisotopesConceptsTarget lesion revascularizationBalloon/artery ratioLesion revascularizationRecurrent ISRGeographic missArtery ratioStent restenosisPrimary catheter-based interventionMultivariate logistic regression analysisBeta-radiation therapyPredictors of recurrentRecurrence of stenosisTreatment of ISRLarge multicenter trialsMinimum lumen diameterCatheter-based interventionsPreliminary univariate analysisLogistic regression analysisIntravascular ultrasound parametersCohort patientsIndependent predictorsMulticenter trialDiameter stenosisUnivariate analysisBalloon sizingAngiographic Results of the First Human Experience With the Biolimus A9 Drug-Eluting Stent for De Novo Coronary Lesions
Costa RA, Lansky AJ, Abizaid A, Müeller R, Tsuchiya Y, Mori K, Cristea E, Leon MB, Sousa JE, Schmidt T, Hauptmann KE, Grube E. Angiographic Results of the First Human Experience With the Biolimus A9 Drug-Eluting Stent for De Novo Coronary Lesions. The American Journal Of Cardiology 2006, 98: 443-446. PMID: 16893694, DOI: 10.1016/j.amjcard.2006.02.051.Peer-Reviewed Original ResearchConceptsNovo coronary lesionsCoronary lesionsDe novo coronary lesionsNoncomplex coronary lesionsLate lumen lossFirst human experienceDrug-eluting stentsAngiographic characteristicsAngiographic findingsAngiographic resultsLumen lossStent groupBaseline lesionsStent restenosisControl groupLesionsStentsUncoated stentsDistal edgeGroupPatientsHyperplasiaRestenosisOutcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound
Kimura M, Mintz GS, Carlier S, Takebayashi H, Fujii K, Sano K, Yasuda T, Costa RA, Costa JR, Quen J, Tanaka K, Lui J, Weisz G, Moussa I, Dangas G, Mehran R, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB. Outcome After Acute Incomplete Sirolimus-Eluting Stent Apposition as Assessed by Serial Intravascular Ultrasound. The American Journal Of Cardiology 2006, 98: 436-442. PMID: 16893693, DOI: 10.1016/j.amjcard.2006.02.050.Peer-Reviewed Original ResearchConceptsIncomplete stent appositionSES implantationStent appositionSirolimus-eluting stent implantationComplete resolution groupIntravascular ultrasound findingsIncidence of restenosisSerial intravascular ultrasoundConsecutive patientsStent thrombosisStent implantationUltrasound findingsPlaque areaAneurysm formationStent restenosisIntravascular ultrasoundPatientsLumen areaStent strutsGreater decreaseVessel wallThrombosisRestenosisLesionsGreater increaseEffect of Everolimus-Eluting Stents in Different Vessel Sizes (from the Pooled FUTURE I and II Trials)
Tsuchiya Y, Lansky AJ, Costa RA, Mehran R, Pietras C, Shimada Y, Sonoda S, Cristea E, Negoita M, Dangas GD, Moses JW, Leon MB, Fitzgerald PJ, Müller R, Störger H, Hauptmann KE, Grube E. Effect of Everolimus-Eluting Stents in Different Vessel Sizes (from the Pooled FUTURE I and II Trials). The American Journal Of Cardiology 2006, 98: 464-469. PMID: 16893698, DOI: 10.1016/j.amjcard.2006.02.054.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Vessel Prosthesis ImplantationCoated Materials, BiocompatibleCoronary AngiographyCoronary RestenosisCoronary VesselsEverolimusFemaleFollow-Up StudiesHumansImmunosuppressive AgentsMaleMiddle AgedProspective StudiesProsthesis DesignSirolimusStentsTreatment OutcomeUltrasonography, InterventionalConceptsBare metal stentsDe novo coronary lesionsNovo coronary lesionsCoronary lesionsNeointimal proliferationStent late lumen lossMid-term outcomesLate lumen lossEverolimus-Eluting StentsQuantitative coronary angiographyMinimum lumen areaVessel sizeII trialCoronary angiographyI trialIncomplete appositionLumen lossStent thrombosisAneurysm formationStent restenosisIntravascular ultrasoundMetal stentsReference diameterLumen areaPatientsA multicenter, randomized, dose-finding study of gamma intracoronary radiation therapy to inhibit recurrent restenosis after stenting.
Price MJ, Moses JW, Leon MB, Mehran R, Negoita M, Lansky A, Collins M, Giap H, Lin R, Jani S, Steuterman S, Balter S, Dalton J, Lipsztein R, Tripuraneni P, Teirstein PS. A multicenter, randomized, dose-finding study of gamma intracoronary radiation therapy to inhibit recurrent restenosis after stenting. Journal Of Invasive Cardiology 2006, 18: 169-73. PMID: 16732060.Peer-Reviewed Original ResearchConceptsIntracoronary radiation therapyStent restenosisRadiation therapyLesion late lossTarget lesion revascularizationHigh-dose groupDose-finding studySignificant clinical problemBare metal stentsRadiation dose prescriptionHigh radiation doseBinary restenosisLesion revascularizationRecurrent restenosisVessel revascularizationAdverse eventsCoronary interventionRecurrent stenosisComposite endpointRandomized studyDose groupClinical eventsMyocardial infarctionRadiation failureGy group
2005
Angiographic and clinical outcomes at 8 months of cutting balloon angioplasty and β‐brachytherapy for native vessel in‐stent restenosis (BETACUT): Results from a stopped randomized controlled trial
Schlüter M, Tübler T, Lansky AJ, Kähler S, Berger J, Mathey DG, Schofer J. Angiographic and clinical outcomes at 8 months of cutting balloon angioplasty and β‐brachytherapy for native vessel in‐stent restenosis (BETACUT): Results from a stopped randomized controlled trial. Catheterization And Cardiovascular Interventions 2005, 66: 320-326. PMID: 16216024, DOI: 10.1002/ccd.20517.Peer-Reviewed Original ResearchConceptsStandard balloonClinical outcomesCB angioplastyBalloon angioplastyStent restenosisInterim analysisMajor adverse cardiac eventsNative vesselsAdverse cardiac eventsOverall patient populationImmediate angiographic outcomeTreatment of choiceQuantitative coronary angiographyΒ-brachytherapyAngiographic restenosisBeta-radiation treatmentLesion revascularizationAngiographic outcomesCardiac eventsConsecutive patientsCoronary angiographyStudy armsIntracoronary brachytherapyPatient populationTreatment modalitiesTwo-year clinical follow-up of 90Sr/90 Y β-radiation versus placebo control for the treatment of in-stent restenosis
Silber S, Popma JJ, Suntharalingam M, Lansky AJ, Heuser RR, Speiser B, Teirstein PS, Bass T, O'Neill W, Lasala J, Reisman M, Sharma SK, Kuntz RE, Bonan R, Investigators F. Two-year clinical follow-up of 90Sr/90 Y β-radiation versus placebo control for the treatment of in-stent restenosis. American Heart Journal 2005, 149: 689-694. PMID: 15990754, DOI: 10.1016/j.ahj.2004.05.061.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAnticoagulantsBeta ParticlesBrachytherapyCoronary AngiographyCoronary DiseaseCoronary RestenosisDiabetes ComplicationsDisease-Free SurvivalFemaleFollow-Up StudiesHumansLife TablesMaleMiddle AgedPrognosisStentsStrontium RadioisotopesThrombophiliaTreatment OutcomeYttrium RadioisotopesConceptsMajor adverse cardiac eventsTarget vessel revascularizationStent restenosisIntracoronary brachytherapyOriginal patientsPrimary safety end pointTwo-year clinical outcomesPlacebo-controlled randomized trialEnd pointAdverse cardiac eventsPlacebo-controlled studyPrimary end pointSafety end pointKaplan-Meier analysisInitial beneficial effectsRestenosis TrialVessel revascularizationCardiac eventsPlacebo armClinical followActive treatmentClinical outcomesRandomized trialsPlacebo controlPatientsAngiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial)
Costa RA, Lansky AJ, Mintz GS, Mehran R, Tsuchiya Y, Negoita M, Gilutz Y, Nikolsky E, Fahy M, Pop R, Cristea E, Carlier S, Dangas G, Stone GW, Leon MB, Müller R, Techen G, Grube E. Angiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial). The American Journal Of Cardiology 2005, 95: 113-116. PMID: 15619406, DOI: 10.1016/j.amjcard.2004.08.074.Peer-Reviewed Original ResearchConceptsCoronary lesionsDe novo coronary lesionsStent late lumen lossNoncomplex coronary lesionsSegment diameter stenosisNovo coronary lesionsLate lumen lossEverolimus-eluting stentsFirst human experienceMetallic stent groupEdge restenosisAngiographic characteristicsSegment restenosisAngiographic findingsAngiographic resultsStent thrombosisDiameter stenosisLumen lossStent groupAneurysm formationStent restenosisMetallic stentsRestenosisLesionsStents