2023
Cerebral embolic protection during transcatheter heart interventions.
Jimenez Diaz V, Kapadia S, Linke A, Mylotte D, Lansky A, Grube E, Settergren M, Puri R. Cerebral embolic protection during transcatheter heart interventions. EuroIntervention 2023, 19: 549-570. PMID: 37720969, PMCID: PMC10495748, DOI: 10.4244/eij-d-23-00166.Peer-Reviewed Original ResearchConceptsCerebral embolic protection devicesTranscatheter aortic valve replacementNew cerebral lesionsMajority of patientsCerebral lesionsTransfemoral transcatheter aortic valve replacementHeart interventionsCerebral embolic protectionAortic valve replacementEmbolic protection devicesBrain imaging studiesPrimary endpointDevastating complicationPeriprocedural strokeValve replacementEmbolic protectionEmbolic showerApparent strokeCerebral embolisationTranscatheter proceduresSpecific trialsImaging studiesStrokePatientsLesions
2022
E-19 | Sex-Specific 1-Year Outcomes in Coronary Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Lesions: A Patient-Level Pooled Analysis of the Disrupt CAD III and CAD IV Studies
Lansky A, Kearney K, Abbott J, Saito S, Hill J, Kereiakes D. E-19 | Sex-Specific 1-Year Outcomes in Coronary Intravascular Lithotripsy for Treatment of Severely Calcified Coronary Lesions: A Patient-Level Pooled Analysis of the Disrupt CAD III and CAD IV Studies. Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 1: 100279. DOI: 10.1016/j.jscai.2022.100279.Peer-Reviewed Original ResearchAngiographic Lesion Discordance in Women Presenting With Ischemic Heart Disease: Comparison of Visual Assessment, Quantitative Coronary Angiography, and Quantitative Flow Ratio.
Gitto M, Saito Y, Taoutel R, Schneider MD, Papoutsidakis N, Ardito S, Henry G, Cristea E, Lansky AJ, Altin SE. Angiographic Lesion Discordance in Women Presenting With Ischemic Heart Disease: Comparison of Visual Assessment, Quantitative Coronary Angiography, and Quantitative Flow Ratio. Journal Of Invasive Cardiology 2022, 34: e202-e209. PMID: 35089162, DOI: 10.25270/jic/21.00146.Peer-Reviewed Original ResearchConceptsQuantitative coronary angiographyIschemic heart diseaseQuantitative flow ratioStress perfusion imagingDiameter stenosisCoronary angiographyIschemic symptomsCoronary revascularizationHeart diseasePerfusion imagingStenosis severityIndependent core laboratoryCohort of womenVisual assessmentCoronary stenosis severityConsecutive patientsAngiographic severityCoronary stenosisLesion assessmentClinical practiceCore laboratoryLesionsAngiographyWomenBlinded operators
2019
First-in-Human Study of Paclitaxel Drug-Coated Chocolate Coronary Percutaneous Transluminal Coronary Angioplasty Balloon Catheter in De Novo Coronary Artery Lesions
Garcia-Lithgow C, Tirziu D, Zhou S, Bouras G, Shah T, Grubman D, Javier JJ, Mustapha JA, Abizaid A, Lansky AJ. First-in-Human Study of Paclitaxel Drug-Coated Chocolate Coronary Percutaneous Transluminal Coronary Angioplasty Balloon Catheter in De Novo Coronary Artery Lesions. JACC Cardiovascular Interventions 2019, 12: 2568-2570. PMID: 31857033, DOI: 10.1016/j.jcin.2019.08.044.Peer-Reviewed Original ResearchTreating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study
Gray WA, Cardenas JA, Brodmann M, Werner M, Bernardo NI, George JC, Lansky A. Treating Post-Angioplasty Dissection in the Femoropopliteal Arteries Using the Tack Endovascular System 12-Month Results From the TOBA II Study. JACC Cardiovascular Interventions 2019, 12: 2375-2384. PMID: 31806218, DOI: 10.1016/j.jcin.2019.08.005.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, BalloonBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationEuropeFemaleFemoral ArteryHumansMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProspective StudiesProsthesis DesignRisk FactorsStentsTime FactorsTreatment OutcomeUnited StatesVascular Access DevicesVascular PatencyVascular System InjuriesConceptsProximal popliteal arteryDrug-coated balloonsSuperficial femoral arteryPlain balloonPopliteal arteryFemoral arteryTack Endovascular SystemLong-term outcomesDCB angioplastyEfficacy endpointPrimary patencyResidual stenosisRestenotic lesionsMulticenter studyFemoropopliteal arteriesEndovascular SystemAngioplastyArteryClassification 2DissectionLesionsBalloonStenosisPatencyPatients
2018
TCT-132 Balloon-Expandable ePTFE-Covered Stent for Obstructive Lesions in the Iliac Artery: 24-Month Results from the BOLSTER Trial
Bouras G, Laird J, Zeller T, Holden A, Zhou S, Mena-Hurtado C, Cristea E, Lansky A, Lansky A. TCT-132 Balloon-Expandable ePTFE-Covered Stent for Obstructive Lesions in the Iliac Artery: 24-Month Results from the BOLSTER Trial. Journal Of The American College Of Cardiology 2018, 72: b57. DOI: 10.1016/j.jacc.2018.08.1238.Peer-Reviewed Original Research
2017
TCT-640 24 Month Results From a First-In-Human Data on the Paclitaxel Drug-Coated Chocolate Coronary PTCA Balloon Catheters in De-Novo Coronary Lesions
Bouras G, Abizaid A, Lithgow C, Cristea E, Lansky A. TCT-640 24 Month Results From a First-In-Human Data on the Paclitaxel Drug-Coated Chocolate Coronary PTCA Balloon Catheters in De-Novo Coronary Lesions. Journal Of The American College Of Cardiology 2017, 70: b282. DOI: 10.1016/j.jacc.2017.09.889.Peer-Reviewed Original Research
2016
TCT-777 Safety and Performance of the Shockwave Medical Lithoplasty® System in treating calcified peripheral vascular lesions: 6-Month Results from the two-phase DISRUPT PAD Study
Brinton T, Brodmann M, Werner M, Tepe G, Holden A, Scheinert D, Wolf F, Torsello G, Lansky A, Jaff M, Zeller T. TCT-777 Safety and Performance of the Shockwave Medical Lithoplasty® System in treating calcified peripheral vascular lesions: 6-Month Results from the two-phase DISRUPT PAD Study. Journal Of The American College Of Cardiology 2016, 68: b314. DOI: 10.1016/j.jacc.2016.09.808.Peer-Reviewed Original Research
2015
The TriGuard embolic deflection device for prevention of stroke and cerebral embolization during transcatheter aortic valve replacement
Baumbach A, Pietras C, Lansky A. The TriGuard embolic deflection device for prevention of stroke and cerebral embolization during transcatheter aortic valve replacement. Expert Review Of Medical Devices 2015, 12: 649-651. PMID: 26364995, DOI: 10.1586/17434440.2015.1086642.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationAortic valve implantationValve implantationTranscatheter aortic valve replacementIschemic cerebral eventsAortic valve replacementPrevention of strokeCerebral embolizationEmbolic strokeCerebral eventsEmbolic eventsValve replacementEmbolic lesionsClinical studiesNeurocognitive impairmentNeurocognitive functionMemory lossVessel ostiumStrokeBrain circulationImplantationEmbolizationOstiumLesionsIncidence
2014
TCT-605 Safety and Efficacy of a Novel Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Lesions: 2-Year Results from the Prospectively Patient-Level Pooled Analysis of the TARGET I and TARGET II Trials
Zhao Y, Xu B, Yang Y, Zhang R, Changsheng M, Li H, Huo Y, Lansky A, Leon M, Gao R. TCT-605 Safety and Efficacy of a Novel Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Lesions: 2-Year Results from the Prospectively Patient-Level Pooled Analysis of the TARGET I and TARGET II Trials. Journal Of The American College Of Cardiology 2014, 64: b176-b177. DOI: 10.1016/j.jacc.2014.07.670.Peer-Reviewed Original ResearchWill this trial change my practice? PRAMI - treatment of bystander coronary lesions in patients undergoing primary PCI for acute STEMI.
Toth GG, Kala P, Lansky A, Baumbach A. Will this trial change my practice? PRAMI - treatment of bystander coronary lesions in patients undergoing primary PCI for acute STEMI. EuroIntervention 2014, 10: 411-2. PMID: 25042272, DOI: 10.4244/eijv10i3a70.Peer-Reviewed Original Research
2013
TCT-20 Two-Year Clinical Follow-Up of the FIREHAWK Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting Stent in the Treatment of Patients with De Novo Native Coronary Artery Lesions: The TARGET I Trial
Xu B, Gao R, Lansky A, Yang Y, Changsheng M, Han Y, Chen S, Li H, Zhang R, Fu G, Yuan Z, Huo Y, Li W, Zhao Y, Leon M. TCT-20 Two-Year Clinical Follow-Up of the FIREHAWK Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting Stent in the Treatment of Patients with De Novo Native Coronary Artery Lesions: The TARGET I Trial. Journal Of The American College Of Cardiology 2013, 62: b7-b8. DOI: 10.1016/j.jacc.2013.08.748.Peer-Reviewed Original ResearchDe novo native coronary artery lesionsBiodegradable Polymer Sirolimus-Eluting StentNovo native coronary artery lesionsNative coronary artery lesionsCoronary artery lesionsSirolimus-Eluting StentsTreatment of patientsTwo-Year ClinicalAbluminal grooveArtery lesionsI trialPatientsClinicalLesionsStentsTrialsTCT-181 Safety and Efficacy of a Novel Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Lesions: 12-Month Results from the Prospectively Patient-Level Pooled Analysis of the TARGET I and TARGET II Trials
Gao R, Xu B, Lansky A, Yang Y, Zhang R, Changsheng M, Li H, Chen S, Han Y, Yuan Z, Huo Y, Li W, Zhao Y, Leon M. TCT-181 Safety and Efficacy of a Novel Abluminal Groove-Filled Biodegradable Polymer Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Lesions: 12-Month Results from the Prospectively Patient-Level Pooled Analysis of the TARGET I and TARGET II Trials. Journal Of The American College Of Cardiology 2013, 62: b59. DOI: 10.1016/j.jacc.2013.08.915.Peer-Reviewed Original ResearchClinical implications for diffusion‐weighted MRI brain lesions associated with transcatheter aortic valve replacement
Meller SM, Baumbach A, Brickman AM, Lansky AJ. Clinical implications for diffusion‐weighted MRI brain lesions associated with transcatheter aortic valve replacement. Catheterization And Cardiovascular Interventions 2013, 83: 502-508. PMID: 23460315, DOI: 10.1002/ccd.24904.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementSilent strokeValve replacementCerebral embolic protection devicesDiffusion-weighted magnetic resonance imagingEmbolic protection devicesCerebral protection devicesMRI brain lesionsPotential therapeutic optionQuality of lifeLong-term cognitive consequencesMagnetic resonance imagingNeurological complicationsAortic stenosisImproved survivalNew lesionsEmbolic lesionsTherapeutic optionsBrain lesionsRisk candidatesCognitive declineResonance imagingClinical implicationsLesionsComparison of Clinical Interpretation With Visual Assessment and Quantitative Coronary Angiography in Patients Undergoing Percutaneous Coronary Intervention in Contemporary Practice
Nallamothu BK, Spertus JA, Lansky AJ, Cohen DJ, Jones PG, Kureshi F, Dehmer GJ, Drozda JP, Walsh MN, Brush JE, Koenig GC, Waites TF, Gantt DS, Kichura G, Chazal RA, O’Brien P, Valentine CM, Rumsfeld JS, Reiber JH, Elmore JG, Krumholz RA, Weaver WD, Krumholz HM. Comparison of Clinical Interpretation With Visual Assessment and Quantitative Coronary Angiography in Patients Undergoing Percutaneous Coronary Intervention in Contemporary Practice. Circulation 2013, 127: 1793-1800. PMID: 23470859, PMCID: PMC3908681, DOI: 10.1161/circulationaha.113.001952.Peer-Reviewed Original ResearchConceptsQuantitative coronary angiographyPercent diameter stenosisPercutaneous coronary interventionDiameter stenosisCoronary interventionCoronary angiographyCoronary lesionsClinical interpretationAngiographic interpretationStenosis severityHigher percent diameter stenosisMedian percent diameter stenosisElective percutaneous coronary interventionMean differenceCoronary stenosis severityIntermediate lesionsUS hospitalsStenosisLesionsAngiographyPatientsInterventionSeverityVisual assessmentSuch findings
2012
Bifurcation Quantitative Coronary Angiography
Ng V, Lansky A. Bifurcation Quantitative Coronary Angiography. 2012, 121-135. DOI: 10.1002/9781444347005.ch13.Peer-Reviewed Original ResearchCHARACTERISTICS AND CLINICAL SIGNIFICANCE OF ANGIOGRAPHICALLY MILD LESIONS IN ACUTE CORONARY SYNDROMES: INSIGHTS FROM THE PROSPECT STUDY
Brener S, Mintz G, Cristea E, Weisz G, Maehara A, McPherson J, Marso S, Farhat N, Botker H, Dressler O, Xu K, Templin B, Zhang Z, Lansky A, de Bruyne B, Serruys P, Stone G. CHARACTERISTICS AND CLINICAL SIGNIFICANCE OF ANGIOGRAPHICALLY MILD LESIONS IN ACUTE CORONARY SYNDROMES: INSIGHTS FROM THE PROSPECT STUDY. Journal Of The American College Of Cardiology 2012, 59: e352. DOI: 10.1016/s0735-1097(12)60353-2.Peer-Reviewed Original ResearchLongitudinal Distribution of Plaque Burden and Necrotic Core–Rich Plaques in Nonculprit Lesions of Patients Presenting With Acute Coronary Syndromes
Wykrzykowska JJ, Mintz GS, Garcia-Garcia HM, Maehara A, Fahy M, Xu K, Inguez A, Fajadet J, Lansky A, Templin B, Zhang Z, de Bruyne B, Weisz G, Serruys PW, Stone GW. Longitudinal Distribution of Plaque Burden and Necrotic Core–Rich Plaques in Nonculprit Lesions of Patients Presenting With Acute Coronary Syndromes. JACC Cardiovascular Imaging 2012, 5: s10-s18. PMID: 22421223, DOI: 10.1016/j.jcmg.2012.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryChi-Square DistributionCoronary Artery DiseaseCoronary StenosisCoronary VesselsEuropeFemaleHumansLipidsMaleMiddle AgedMyocardial InfarctionNecrosisPhenotypePlaque, AtheroscleroticPredictive Value of TestsProspective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesConceptsLeft main coronary arteryVirtual histology intravascular ultrasoundAcute coronary syndromePlaque burdenDistal coronary treeNonculprit lesionsCoronary syndromeVH-TCFACoronary arteryCoronary treeNecrotic core contentAcute coronary eventsEpicardial coronary arteriesMain coronary arteryAtherosclerotic plaque burdenAcute myocardial infarctionLong segmentCoronary eventsAnterior descendingMyocardial infarctionVulnerable plaquesProportion of NCsArteryLesionsPROSPECT studyCharacteristics and Clinical Significance of Angiographically Mild Lesions in Acute Coronary Syndromes
Brener SJ, Mintz GS, Cristea E, Weisz G, Maehara A, McPherson JA, Marso SP, Farhat N, Botker HE, Dressler O, Xu K, Templin B, Zhang Z, Lansky AJ, de Bruyne B, Serruys PW, Stone GW. Characteristics and Clinical Significance of Angiographically Mild Lesions in Acute Coronary Syndromes. JACC Cardiovascular Imaging 2012, 5: s86-s94. PMID: 22421235, DOI: 10.1016/j.jcmg.2011.12.007.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary StenosisEuropeFemaleFibrosisHumansKaplan-Meier EstimateMaleMiddle AgedNecrosisPlaque, AtheroscleroticPredictive Value of TestsProportional Hazards ModelsProspective StudiesRecurrenceRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesVascular CalcificationConceptsAcute coronary syndromePercutaneous coronary interventionMajor adverse cardiac eventsAdverse cardiac eventsCoronary syndromeNC lesionsCoronary interventionCardiac eventsDiameter stenosisSuccessful percutaneous coronary interventionMedian diameter stenosisRecurrent ischemic eventsThin-cap fibroatheromaNonculprit lesionsIschemic eventsUntreated lesionsClinical eventsClinical significanceMild lesionsPatientsLesionsNormal segmentsOne-halfSyndromeRecurrent events
2011
Discrepancy in the assessment of jailed side branch lesions by visual estimation and quantitative coronary angiographic analysis
Shin D, Koo B, Waseda K, Park KW, Kim H, Corral M, Lansky A, Honda Y, Fearon WF, Fitzgerald PJ. Discrepancy in the assessment of jailed side branch lesions by visual estimation and quantitative coronary angiographic analysis. Catheterization And Cardiovascular Interventions 2011, 78: 720-726. PMID: 22025472, DOI: 10.1002/ccd.23049.Peer-Reviewed Original ResearchConceptsMean minimum lumen diameterQuantitative coronary angiographyFractional flow reserveSide branch lesionsDiameter stenosisSB lesionsIntraclass correlation coefficientBranch lesionsQuantitative coronary angiographic analysisCoronary angiographic analysisMinimum lumen diameterVisual estimationCoronary angiographyPressure trialAngiographic analysisAngiographic assessmentFlow reserveCore laboratoryStenosisReference diameterLesionsLumen diameterLesion lengthFunctional significance