2019
P869Predictive value of the endothelial shear stress distribution in three-dimensional quantitative coronary angiography models in detecting vulnerable plaques
Zanchin T, Bourantas C, Torii R, Serruys P, Karagiannis A, Ramasamy A, Onuma Y, Mathur A, Baumbach A, Windecker S, Lansky A, Maehara A, Stone P, Raeber L, Stone G. P869Predictive value of the endothelial shear stress distribution in three-dimensional quantitative coronary angiography models in detecting vulnerable plaques. European Heart Journal 2019, 40: ehz747.0466. DOI: 10.1093/eurheartj/ehz747.0466.Peer-Reviewed Original ResearchHigh endothelial shear stressEndothelial shear stressLow endothelial shear stressQuantitative coronary angiographyMinimum lumen areaPd/PaVulnerable plaquesPlaque burdenSmaller minimum lumen areaMajor adverse cardiac eventsLarge-scale prospective studiesBaseline plaque characteristicsHigh-risk anatomyAdverse cardiac eventsNon-culprit lesionsOnly independent predictorUseful prognostic informationHigh-risk plaquesESS valuesNC-MACECardiac eventsCoronary atherosclerosisCoronary angiographyIndependent predictorsMultivariable analysis
2012
Definitions and Methodology for the Grayscale and Radiofrequency Intravascular Ultrasound and Coronary Angiographic Analyses
Maehara A, Cristea E, Mintz GS, Lansky AJ, Dressler O, Biro S, Templin B, Virmani R, de Bruyne B, Serruys PW, Stone GW. Definitions and Methodology for the Grayscale and Radiofrequency Intravascular Ultrasound and Coronary Angiographic Analyses. JACC Cardiovascular Imaging 2012, 5: s1-s9. PMID: 22421222, DOI: 10.1016/j.jcmg.2011.11.019.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary Artery DiseaseCoronary StenosisDisease ProgressionEuropeFemaleFibrosisHumansImage Processing, Computer-AssistedMaleMiddle AgedMultivariate AnalysisNeointimaPredictive Value of TestsProspective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTerminology as TopicTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesVascular CalcificationConceptsThin-cap fibroatheromaAdverse cardiovascular eventsRadiofrequency intravascular ultrasoundNatural history studiesNonculprit lesionsPlaque burdenCardiovascular eventsLuminal areaIntravascular ultrasoundVH thin-cap fibroatheromaMajor adverse cardiovascular eventsFuture adverse cardiovascular eventsCoronary angiographic analysisCoronary artery ostiumThick-cap fibroatheromaLarger plaque burdenVirtual histologyMinimal luminal areaPathological intimal thickeningSmall luminal areaCoronary artery imagingHistory studiesSide branchesCoronary atherosclerosisCulprit lesion
2011
A Prospective Natural-History Study of Coronary Atherosclerosis
Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, Parise H, Templin B, White R, Zhang Z, Serruys PW. A Prospective Natural-History Study of Coronary Atherosclerosis. New England Journal Of Medicine 2011, 364: 226-235. PMID: 21247313, DOI: 10.1056/nejmoa1002358.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDisease ProgressionFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPatient ReadmissionProportional Hazards ModelsProspective StudiesRecurrenceRisk FactorsUltrasonography, InterventionalConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsAcute coronary syndromeNonculprit lesionsPercutaneous coronary interventionThin-cap fibroatheromaCardiovascular eventsCoronary syndromeCulprit lesionCoronary interventionPlaque burdenIntravascular ultrasonographyLuminal areaSubsequent major adverse cardiovascular eventsLesion-related risk factorsMild coronary artery stenosisProspective natural history studyLarger plaque burdenCoronary artery stenosisMinimal luminal areaNatural history studiesRecurrent eventsSmall luminal areaMedian followCoronary atherosclerosis
2010
IMPACT OF GENDER ON THE EXTENT OF CORONARY ATHEROSCLEROSIS AND PLAQUE CHARACTERIZATION IN ACUTE CORONARY SYNDROMES: INSIGHTS FROM THE PROSPECT TRIAL
Lansky A, Maehara A, Mintz G, Ng V, Veldhof S, de Bruyne B, McPherson J, Cristea E, Templin B, Parise H, Fahy M, Serruys P, Stone G. IMPACT OF GENDER ON THE EXTENT OF CORONARY ATHEROSCLEROSIS AND PLAQUE CHARACTERIZATION IN ACUTE CORONARY SYNDROMES: INSIGHTS FROM THE PROSPECT TRIAL. Journal Of The American College Of Cardiology 2010, 55: a186.e1738. DOI: 10.1016/s0735-1097(10)61739-1.Peer-Reviewed Original Research
2000
Current perspectives on interventional treatment strategies in diabetic patients with coronary artery disease
Kornowski R, Lansky A. Current perspectives on interventional treatment strategies in diabetic patients with coronary artery disease. Catheterization And Cardiovascular Interventions 2000, 50: 245-254. PMID: 10842400, DOI: 10.1002/(sici)1522-726x(200006)50:2<245::aid-ccd22>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseCoronary interventionBypass surgeryArtery diseaseDiabetes mellitusDiabetic patientsClinical outcomesCoronary artery bypass surgeryDiffuse coronary artery diseaseCatheter-based coronary interventionsArtery bypass surgeryCoronary bypass surgeryInterventional treatment strategiesPercutaneous coronary interventionUse of antiplateletAtherosclerosis lesion progressionTarget vessel sizeAdjunctive pharmacologyMore restenosisMultivessel diseaseAtherosclerosis burdenCoronary atherosclerosisCoronary proceduresCoronary sitesAdjunctive pharmacotherapy
1998
Lipid-Lowering Therapy After Coronary Revascularization: The Interventional Cardiologist’s Perspective 11This work was supported by the Cardiology Research Foundation, Washington, DC.
Lansky A, Popma J, Mintz G, Laird J, Saucedo J, Leon M. Lipid-Lowering Therapy After Coronary Revascularization: The Interventional Cardiologist’s Perspective 11This work was supported by the Cardiology Research Foundation, Washington, DC. The American Journal Of Cardiology 1998, 81: 55e-62e. PMID: 9551596, DOI: 10.1016/s0002-9149(98)00199-4.Peer-Reviewed Original ResearchConceptsCoronary eventsCoronary interventionCholesterol levelsAggressive lipid-lowering therapyCardiology Research FoundationLipid-lowering therapyTreatment of stenosisPatients' cholesterol levelsLipid-laden plaqueCoronary revascularizationCoronary atherosclerosisUnderlying diseaseRevascularization proceduresAtherosclerotic progressionCardiologist's practiceAdvanced lesionsCholesterol reductionPlaque accumulationIntravascular ultrasoundOwn carePatientsTherapyInterventionRevascularizationAtherectomy
1997
Comparison of Men Versus Women in Cross-Sectional Area Luminal Narrowing, Quantity of Plaque, Presence of Calcium in Plaque, and Lumen Location in Coronary Arteries by Intravascular Ultrasound in Patients with Stable Angina Pectoris
Kornowski R, Lansky A, Mintz G, Kent K, Pichard A, Satler L, Bucher T, Popma J, Leon M. Comparison of Men Versus Women in Cross-Sectional Area Luminal Narrowing, Quantity of Plaque, Presence of Calcium in Plaque, and Lumen Location in Coronary Arteries by Intravascular Ultrasound in Patients with Stable Angina Pectoris. The American Journal Of Cardiology 1997, 79: 1601-1605. PMID: 9202348, DOI: 10.1016/s0002-9149(97)00206-3.Peer-Reviewed Original ResearchConceptsExternal elastic membraneIntravascular ultrasoundCoronary atherosclerosisPlaque burdenCross-sectional area luminal narrowingPreinterventional intravascular ultrasoundNative coronary lesionsStable angina pectorisMen Versus WomenProximal reference siteBody surface areaComorbid clinical conditionsQuantity of plaqueChronic anginaCoronary interventionAngina pectorisCoronary lesionsLuminal narrowingCoronary arteryIVUS analysisPlaque eccentricityTarget lesionsIVUS measuresClinical conditionsM area