A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice
Nussenzweig M, Schmidt E, Shaw A, Sinn E, Campos-Torres J, Mathey-Prevot B, Pattengale P, Leder P. A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice. Nature 1988, 336: 446-450. PMID: 3143076, DOI: 10.1038/336446a0.Peer-Reviewed Original ResearchMeSH KeywordsAbelson murine leukemia virusAnimalsB-LymphocytesBone MarrowCell Transformation, NeoplasticCell Transformation, ViralEnhancer Elements, GeneticGenes, ImmunoglobulinHematopoietic Stem CellsHumansImmunoglobulin mu-ChainsLymphomaMiceMice, TransgenicPhenotypeProto-Oncogene ProteinsProto-Oncogene Proteins c-mycProto-OncogenesRNA, Messenger