2023
Simplified sewerage to prevent urban leptospirosis transmission: a cluster non-randomised controlled trial protocol in disadvantaged urban communities of Salvador, Brazil
Cremonese C, Souza F, Palma F, Sodré J, Brito R, dos Santos Ribeiro P, Santana J, Coelho R, Ticona J, Nazaré R, de Oliveira D, Silva C, Eyre M, de Araújo Mendes V, Knee J, Ristow P, Stauber C, López Y, Giorgi E, Diggle P, Reis M, Cumming O, Ko A, Costa F. Simplified sewerage to prevent urban leptospirosis transmission: a cluster non-randomised controlled trial protocol in disadvantaged urban communities of Salvador, Brazil. BMJ Open 2023, 13: e065009. PMID: 37355266, PMCID: PMC10314607, DOI: 10.1136/bmjopen-2022-065009.Peer-Reviewed Original ResearchConceptsBrazilian Clinical Trials RegistryNon-randomised interventionClinical Trials RegistryNational Research Ethics CommitteeMajor health problemQuasi-experimental study designIntervention-control pairsRoute of exposureSecondary outcomesPrimary outcomeTrials RegistryResearch Ethics CommitteeRisk of exposureSerological measurementsStudy protocolTrial protocolPeer-reviewed publicationsHealth problemsControl clustersAetiological agentInfected rodentsStudy designLeptospirosis transmissionEthics CommitteeUrban slumsBartonella in Norway rats (Rattus norvegicus) from the urban slum environment in Brazil
Zeppelini C, Oliveira D, Kosoy M, Reis M, Ko A, Childs J, Costa F. Bartonella in Norway rats (Rattus norvegicus) from the urban slum environment in Brazil. Anais Da Academia Brasileira De Ciências 2023, 95: e20220809. PMID: 37909607, DOI: 10.1590/0001-3765202320220809.Peer-Reviewed Original Research
2022
Rickettsial Infections Causing Acute Febrile Illness in Urban Slums, Brazil - Volume 28, Number 10—October 2022 - Emerging Infectious Diseases journal - CDC
Fournier JB, Blanton LS, Nery N, Wunder EA, Costa F, Reis MG, Ribeiro GS, Walker DH, Ko AI. Rickettsial Infections Causing Acute Febrile Illness in Urban Slums, Brazil - Volume 28, Number 10—October 2022 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2022, 28: 2132-2134. PMID: 36148970, PMCID: PMC9514363, DOI: 10.3201/eid2810.220497.Peer-Reviewed Original ResearchStructural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey
Fofana MO, Nery N, Ticona J, de Andrade Belitardo EMM, Victoriano R, Anjos RO, Portilho MM, de Santana MC, dos Santos LL, de Oliveira D, Cruz JS, Muenker MC, Khouri R, Wunder EA, Hitchings MDT, Johnson O, Reis MG, Ribeiro GS, Cummings DAT, Costa F, Ko AI. Structural factors associated with SARS-CoV-2 infection risk in an urban slum setting in Salvador, Brazil: A cross-sectional survey. PLOS Medicine 2022, 19: e1004093. PMID: 36074784, PMCID: PMC9499230, DOI: 10.1371/journal.pmed.1004093.Peer-Reviewed Original ResearchConceptsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionAcute respiratory syndrome coronavirus 2 infectionSARS-CoV-2 infection riskUrban slumsSyndrome coronavirus 2 infectionSARS-CoV-2 seroprevalenceSARS-CoV-2 incidenceCoronavirus 2 infectionCross-sectional serosurveyMain outcome measuresUrban slum populationPresence of IgGSARS-CoV-2 spike proteinUrban slum communityCross-sectional surveyUrban slum residentsCumulative incidenceMedian ageRisk factorsOutcome measuresStudy populationHigh seroprevalenceMedian dailyPandemic waveGender distribution
2021
Effect of Sewerage on the Contamination of Soil with Pathogenic Leptospira in Urban Slums
Casanovas-Massana A, Souza F, Curry M, de Oliveira D, de Oliveira AS, Eyre MT, Santiago D, Santos M, Serra RMR, Lopes E, Xavier BI, Diggle PJ, Wunder EA, Reis MG, Ko AI, Costa F. Effect of Sewerage on the Contamination of Soil with Pathogenic Leptospira in Urban Slums. Environmental Science And Technology 2021, 55: 15882-15890. PMID: 34767339, PMCID: PMC9302045, DOI: 10.1021/acs.est.1c04916.Peer-Reviewed Original ResearchGenetic Evidence for a Potential Environmental Pathway to Spillover Infection of Rat-Borne Leptospirosis
Casanovas-Massana A, de Oliveira D, Schneider AG, Begon M, Childs JE, Costa F, Reis MG, Ko AI, Wunder EA. Genetic Evidence for a Potential Environmental Pathway to Spillover Infection of Rat-Borne Leptospirosis. The Journal Of Infectious Diseases 2021, 225: 130-134. PMID: 34139761, PMCID: PMC8730487, DOI: 10.1093/infdis/jiab323.Peer-Reviewed Original ResearchConceptsPotential environmental pathwaysEnvironmental reservoirsSpillover infectionsEnvironmental pathwaysHuman leptospirosis casesSevere leptospirosisLeptospirosis infectionLeptospirosis casesMolecular epidemiologyGenetic evidencePathogenic LeptospiraLeptospira interrogansInfectionLeptospirosisUrban slumsSpillover pathwaysRat specimensReservoirPathwayUrban communitiesCommunityEpidemiologyPoverty, sanitation, and Leptospira transmission pathways in residents from four Brazilian slums
Khalil H, Santana R, de Oliveira D, Palma F, Lustosa R, Eyre MT, Carvalho-Pereira T, Reis MG, Ko AI, Diggle PJ, Lopez Y, Begon M, Costa F. Poverty, sanitation, and Leptospira transmission pathways in residents from four Brazilian slums. PLOS Neglected Tropical Diseases 2021, 15: e0009256. PMID: 33788864, PMCID: PMC8041187, DOI: 10.1371/journal.pntd.0009256.Peer-Reviewed Original Research
2019
Coinfection modifies carriage of enzootic and zoonotic parasites in Norway rats from an urban slum
Carvalho‐Pereira T, Souza F, do Nascimento Santos L, Pedra G, Minter A, Bahiense T, Reis M, Ko A, Childs J, da Silva E, Costa F, Begon M. Coinfection modifies carriage of enzootic and zoonotic parasites in Norway rats from an urban slum. Ecosphere 2019, 10 DOI: 10.1002/ecs2.2887.Peer-Reviewed Original ResearchUrban slumsLoad of parasitesZoonotic parasitesUrban ratsStrongyloides spBrazilian urban slumsIntensity of infectionReduced prevalenceNippostrongylus brasiliensisCoinfectionSignificant associationInfection riskRatsNematode Angiostrongylus cantonensisAngiostrongylus cantonensisInfectionNorway ratsEggs/larvaeCantonensisZoonotic pathogensCorrelation testInterrogansParasitesPopulationSignificant Genetic Impacts Accompany an Urban Rat Control Campaign in Salvador, Brazil
Richardson J, Silveira G, Medrano I, Arietta A, Mariani C, Pertile A, Pereira T, Childs J, Ko A, Costa F, Caccone A. Significant Genetic Impacts Accompany an Urban Rat Control Campaign in Salvador, Brazil. Frontiers In Ecology And Evolution 2019, 7: 115. DOI: 10.3389/fevo.2019.00115.Peer-Reviewed Original Research
2013
Household Food Insecurity and Obesity Risk in an Urban Slum in Brazil
Peterson K, de Sousa Ribeiro G, dos Reis M, Paploski I, Ko A, Salles‐Costa R, Pérez‐Escamilla R. Household Food Insecurity and Obesity Risk in an Urban Slum in Brazil. The FASEB Journal 2013, 27: 243.6-243.6. DOI: 10.1096/fasebj.27.1_supplement.243.6.Peer-Reviewed Original ResearchSevere household food insecurityAbdominal obesityHousehold food insecurityPrevalence of HHFILow fruit intakeOverweight/obeseBrazilian Food Insecurity ScaleHigh-calorie mealUrban slumsUnhealthy dietary behaviorsSelf-reported healthFood Insecurity ScaleFruit intakeObesity riskRisk factorsChronic diseasesDietary intakeDietary behaviorsHealth statusObesityFood insecurityWHO guidelinesOverweightIntakeHousehold food preparation
2008
Impact of Environment and Social Gradient on Leptospira Infection in Urban Slums
Reis RB, Ribeiro GS, Felzemburgh RD, Santana FS, Mohr S, Melendez AX, Queiroz A, Santos AC, Ravines RR, Tassinari WS, Carvalho MS, Reis MG, Ko AI. Impact of Environment and Social Gradient on Leptospira Infection in Urban Slums. PLOS Neglected Tropical Diseases 2008, 2: e228. PMID: 18431445, PMCID: PMC2292260, DOI: 10.1371/journal.pntd.0000228.Peer-Reviewed Original ResearchConceptsLeptospira antibodiesLeptospira infectionRisk factorsIndependent risk factorSocioeconomic statusUrban slumsCommunity-based surveyPopulation-based informationHousehold environmental factorsPoisson regression modelsBlack raceOverall prevalencePrior infectionHealth outcomesHealth problemsUrban leptospirosisInfection riskInfectionSocial gradientUnequal health outcomesEffective preventionLeptospira transmissionTransmission determinantsAntibodiesSystem survey