2024
Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia
Bai H, Varsanik M, Thaxton C, Ohashi Y, Gonzalez L, Zhang W, Aoyagi Y, Kano M, Yatsula B, Li Z, Pocivavsek L, Dardik A. Disturbed flow in the juxta-anastomotic area of an arteriovenous fistula correlates with endothelial loss, acute thrombus formation, and neointimal hyperplasia. AJP Heart And Circulatory Physiology 2024, 326: h1446-h1461. PMID: 38578237, PMCID: PMC11380968, DOI: 10.1152/ajpheart.00054.2024.Peer-Reviewed Original ResearchConceptsEndothelial cell lossOutflow veinChronic kidney diseaseJuxta-anastomotic areaMouse AVF modelNeointimal hyperplasiaThrombus formationAcute thrombus formationCell lossHuman AVF maturationGene OntologyAVF maturationAVF patencyEarly thrombus formationArteriovenous fistulaC57BL/6 miceClinical failureWistar ratsEndothelial lossKidney diseaseImmune responseEndothelial cellsHyperplasiaMiceAVF
2008
Periprocedural Drug Therapy in Carotid Artery Stenting: The Need for More Evidence
Gortler D, Schlösser FJ, Muhs BE, Nelson MA, Dardik† A. Periprocedural Drug Therapy in Carotid Artery Stenting: The Need for More Evidence. Vascular 2008, 16: 303-309. PMID: 19344586, DOI: 10.2310/6670.2008.00081.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCarotid endarterectomyLarge prospective cohort studyDual antiplatelet therapyProspective cohort studyCarotid artery stentingCohort studyArtery stentingPeriprocedural settingDrug therapyPharmacologic agentsCarotid arteryHigh riskPatient careTherapyOptimal outcomesRegimenGood validityPatientsMore evidenceOutcomesOptimal timeClopidogrelEndarterectomyMedicationsStenting