2024
Patient-specific, multiscale modelling of neointimal hyperplasia in lower-limb vein grafts using readily available clinical data
Ninno F, Chiastra C, Donadoni F, Dardik A, Strosberg D, Aboian E, Tsui J, Balabani S, Díaz-Zuccarini V. Patient-specific, multiscale modelling of neointimal hyperplasia in lower-limb vein grafts using readily available clinical data. Journal Of Biomechanics 2024, 177: 112428. PMID: 39561605, DOI: 10.1016/j.jbiomech.2024.112428.Peer-Reviewed Original ResearchTime-averaged wall shear stressInflow boundary conditionsBoundary conditionsWall shear stressShear stressMultiscale modelWaveform shapePeripheral arterial diseaseNeointimal hyperplasiaVein graftsClinical dataMechanobiological mechanismsGraft responseMultiscale in silico modelSystolic acceleration time
2012
Neointimal Hyperplasia: Basic Considerations
Model L, Dardik A. Neointimal Hyperplasia: Basic Considerations. 2012, 178-196. DOI: 10.1002/9781118481370.ch10.ChaptersSmooth muscle cell proliferationMuscle cell proliferationNeointimal hyperplasiaIII trialsBypass graft failureCell proliferationVein graft adaptationVein graft restenosisExtracellular matrix depositionGraft failureVein graftsVascular surgeonsVascular surgeryGraft restenosisGraft adaptationNew molecular mechanismHyperplasiaTrialsRestenosisMatrix depositionBody responseArterial environmentMolecular mechanismsDisappointing failuresProliferation
2010
Umbilical Vein Grafts for Lower Limb Revascularization
Dardik A, Dardik H. Umbilical Vein Grafts for Lower Limb Revascularization. 2010, 189-198. DOI: 10.1007/978-1-84882-718-9_19.Chapters
1988
A decade of experience with the glutaraldehyde-tanned human umbilical cord vein graft for revascularization of the lower limb
Dardik H, Miller N, Dardik A, Ibrahim I, Sussman B, Berry S, Wolodiger F, Kahn M, Dardik I. A decade of experience with the glutaraldehyde-tanned human umbilical cord vein graft for revascularization of the lower limb. Journal Of Vascular Surgery 1988, 7: 336-346. DOI: 10.1016/0741-5214(88)90153-x.Peer-Reviewed Original ResearchConceptsGraft failureHuman umbilical cord vein graftAdjunctive distal arteriovenous fistulasCumulative graft patency rateSuccessful graft replacementGraft patency rateLower limb bypassOverall clinical impactDistal arteriovenous fistulaLimited life expectancyOverall infection rateSitu saphenous veinKnee poplitealPopliteal reconstructionAnastomotic aneurysmsFoot gangreneGraft aneurysmGraft thrombosisGraft replacementDistal anastomosisPeroneal bypassVein graftsGraft dilationPatency ratesArteriovenous fistulaA decade of experience with the glutaraldehyde-tanned human umbilical cord vein graft for revascularization of the lower limb.
Dardik H, Miller N, Dardik A, Ibrahim I, Sussman B, Berry S, Wolodiger F, Kahn M, Dardik I. A decade of experience with the glutaraldehyde-tanned human umbilical cord vein graft for revascularization of the lower limb. Journal Of Vascular Surgery 1988, 7: 336-46. PMID: 3123718, DOI: 10.1067/mva.1988.avs0070336.Peer-Reviewed Original ResearchConceptsGraft failureHuman umbilical cord vein graftAdjunctive distal arteriovenous fistulasCumulative graft patency rateSuccessful graft replacementGraft patency rateLower limb bypassOverall clinical impactDistal arteriovenous fistulaLimited life expectancyOverall infection rateSitu saphenous veinKnee poplitealPopliteal reconstructionAnastomotic aneurysmsFoot gangreneGraft aneurysmGraft thrombosisGraft dilatationGraft replacementDistal anastomosisPeroneal bypassVein graftsPatency ratesArteriovenous fistula