2018
Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species
Ayaz A, Agarwal A, Sharma R, Kothandaraman N, Cakar Z, Sikka S. Proteomic analysis of sperm proteins in infertile men with high levels of reactive oxygen species. Andrologia 2018, 50: e13015. PMID: 29656391, DOI: 10.1111/and.13015.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmyloid beta-Protein PrecursorAntigens, NeoplasmF-Box ProteinsHSP70 Heat-Shock ProteinsHumansInfertility, MaleMaleMAP Kinase Kinase Kinase 3Nerve Tissue ProteinsNitric Oxide Synthase Type IIPeptidyl-Dipeptidase AProteomicsReactive Oxygen SpeciesRibosomal ProteinsSmall Ubiquitin-Related Modifier ProteinsSpermatozoaTestisUbiquitinsConceptsReactive oxygen speciesSperm proteinsMale infertilityAngiotensin-converting enzymePost-acrosomal regionPoor sperm qualityLevels of reactive oxygen speciesSperm qualityTesticular environmentInfertile menHeat shock proteinsProteomic analysisHSPA2SpermatozoaExpression profilesOxidative stressRPS27aProteinOxygen speciesMAP3K3Western blottingNeck areaRisk factorsUBL4ASperm
2015
Proteomic analysis of seminal plasma of infertile men with differing levels of reactive oxygen species reveals defective protein turnover
Agarwal A, Ayaz A, Sharma R, Samanta L, Assidi M, Gupta S, Sabanegh E. Proteomic analysis of seminal plasma of infertile men with differing levels of reactive oxygen species reveals defective protein turnover. Fertility And Sterility 2015, 104: e144. DOI: 10.1016/j.fertnstert.2015.07.445.Peer-Reviewed Original ResearchSeminal plasma of infertile menLevels of reactive oxygen speciesInfertile menProteomic analysisReactive oxygen speciesProtein turnoverOxygen speciesSpeciesTurnoverImpact of precise modulation of reactive oxygen species levels on spermatozoa proteins in infertile men
Ayaz A, Agarwal A, Sharma R, Arafa M, Elbardisi H, Cui Z. Impact of precise modulation of reactive oxygen species levels on spermatozoa proteins in infertile men. Clinical Proteomics 2015, 12: 4. PMID: 25972767, PMCID: PMC4429661, DOI: 10.1186/1559-0275-12-4.Peer-Reviewed Original ResearchReactive oxygen species levelsInfertile menReactive oxygen speciesLevels of reactive oxygen speciesMale infertilityROS groupHigher ROS levelsHigher reactive oxygen speciesFertile menExpression of sperm proteinsHigh ROS groupPathology of male infertilityROS levelsGlobal proteomic analysisSperm proteinsSpermatozoa proteinsReactive oxygen species groupIn-gel digestionBioinformatics toolsSpecies levelCellular processesExpressed proteinsReproductive functionProteomic analysisIn-gel