Differential Proteomic Profiling of Spermatozoal Proteins of Infertile Men With Unilateral or Bilateral Varicocele
Agarwal A, Sharma R, Durairajanayagam D, Cui Z, Ayaz A, Gupta S, Willard B, Gopalan B, Sabanegh E. Differential Proteomic Profiling of Spermatozoal Proteins of Infertile Men With Unilateral or Bilateral Varicocele. Urology 2015, 85: 580-588. PMID: 25733269, DOI: 10.1016/j.urology.2014.11.030.Peer-Reviewed Original ResearchConceptsSperm protein profilePost-translational modificationsInfertile menRoutine sperm parametersProtein profilesSodium dodecyl sulfate-polyacrylamide gel electrophoresisDodecyl sulfate-polyacrylamide gel electrophoresisSulfate-polyacrylamide gel electrophoresisFunctional proteomic profilingGel analysis softwareVaricocele-associated male infertilitySperm deoxyribonucleic acid fragmentationComparing spectral countsVaricocele samplesDeoxyribonucleic acid fragmentationProtein foldingSperm parametersDifferential proteomic profilingProtein ubiquitinationCellular functionsSignal transductionGel electrophoresisExpressed proteinsMale infertilityReactive oxygen species