2024
Patients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis
Zubair A, Saab L, Scharer K, Khokhar B. Patients’ experiences with methylcobalamin injections in amyotrophic lateral sclerosis. Brain Circulation 2024, 10: 60-66. PMID: 38655443, PMCID: PMC11034440, DOI: 10.4103/bc.bc_17_23.Peer-Reviewed Original ResearchVitamin B12 injectionsB12 injectionsAmyotrophic lateral sclerosisFood and Drug Administration-approved treatmentPrescribed off-labelQuality of lifeProgressive motor neuron diseaseVitamin B12Pool of patientsMethylcobalamin injectionRandomized controlled trialsLateral sclerosisOff-labelMotor neuron diseaseDisease progressionPatientsMuscle functionSemi-structured interviewsImprove balance
2020
Utility of intrathecal baclofen pump in primary lateral sclerosis
Zubair AS, Raymond M, Patwa HS. Utility of intrathecal baclofen pump in primary lateral sclerosis. Journal Of The Neurological Sciences 2020, 420: 117227. PMID: 33239209, DOI: 10.1016/j.jns.2020.117227.Peer-Reviewed Original ResearchConceptsPrimary lateral sclerosisLateral sclerosisProgressive upper motor neuron dysfunctionLower motor neuron involvementUpper motor neuron dysfunctionMigration of catheterMotor neuron involvementIntrathecal baclofen pumpMotor neuron dysfunctionSpinal cord injuryLower extremity stiffnessAshworth scoreNeuron involvementBaclofen pumpIntrathecal baclofenClinical courseInsidious onsetMuscle spasticityPLS patientsNeuron dysfunctionCord injuryNeurologic conditionsClinical examinationEffective treatmentSpasticity