In vitro inhibition of Cryptosporidium parvum infection by human monoclonal antibodies
Elliot BC, Wisnewski AV, Johnson J, Fenwick-Smith D, Wiest P, Hamer D, Kresina T, Flanigan TP. In vitro inhibition of Cryptosporidium parvum infection by human monoclonal antibodies. Infection And Immunity 1997, 65: 3933-3935. PMID: 9284173, PMCID: PMC175560, DOI: 10.1128/iai.65.9.3933-3935.1997.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntibodies, ProtozoanCells, CulturedCryptosporidiosisCryptosporidium parvumFemaleFluorescent Antibody Technique, IndirectHumansConceptsHuman monoclonal antibodyC. parvum infectionParvum infectionEnzyme-linked immunosorbent assayMonoclonal antibodiesHuman immunodeficiency virus-seronegative womenCell linesHuman enterocyte cell lineHigher specific antibody titersCryptosporidium parvum infectionAnti-Cryptosporidium antibodiesPeripheral blood lymphocytesSpecific antibody titersMonoclonal cell linesEnterocyte cell lineAntibody-secreting clonesC. parvum sporozoitesImmunoglobulin therapyAntibody titersBlood lymphocytesFatal illnessPotential therapyHypo-osmolar electrofusionTumor cell linesInfection