1980
Protection of Mice from Lethal Flaviviral Encephalitis by Adoptive Transfer of Splenic Cells from Donors Infected with Live Virus
Jacoby R, Bhatt P, Schwartz A. Protection of Mice from Lethal Flaviviral Encephalitis by Adoptive Transfer of Splenic Cells from Donors Infected with Live Virus. The Journal Of Infectious Diseases 1980, 141: 617-624. PMID: 6989931, DOI: 10.1093/infdis/141.5.617.Peer-Reviewed Original ResearchConceptsSplenic cellsImmune splenic cellsRabbit antiserum to mouse thymocytesAmelioration of clinical diseaseCell-for-cell basisSusceptible to lethal challengeTransfer of splenic cellsLethal challengeBanzi virusViral replicationCongenic donor miceTransfer of protectionCell-for-cellProtection of miceLive virusFlaviviral infectionsC3H/He recipientsC3H/RV micePrevent viral replicationAdoptive transferDonor miceAdoptive immunityC3H/He miceDeath rateThymus cells
1979
T Cell-Mediated Cytotoxicity for L 929 Fibroblasts Infected with Banzi Virus (Flavivirus)
Sheets P, Schwartz A, Jacoby R, Bhatt P. T Cell-Mediated Cytotoxicity for L 929 Fibroblasts Infected with Banzi Virus (Flavivirus). The Journal Of Infectious Diseases 1979, 140: 384-391. PMID: 315440, DOI: 10.1093/infdis/140.3.384.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArbovirus InfectionsArbovirusesCytotoxicity, ImmunologicKineticsL CellsMiceT-LymphocytesConceptsCytotoxicity of spleen cellsT cell-mediated cytotoxicityBanzi virusCell-mediated cytotoxicityC3H/RV miceSpecific cytotoxicityKiller cellsC3H/He miceSpleen cellsLethal infectionDecreased to background levelsVirus infectionViral inoculationFlaviviral encephalitisL-929 fibroblastsMiceCytotoxicityInfectionBanziCytotoxic activityDaysFibroblastsVirusC3H/RVCells
1976
Genetic Resistance to Lethal Flavivirus Encephalitis. II. Effect of Immunosuppression
Bhatt P, Jacoby R. Genetic Resistance to Lethal Flavivirus Encephalitis. II. Effect of Immunosuppression. The Journal Of Infectious Diseases 1976, 134: 166-173. PMID: 787445, DOI: 10.1093/infdis/134.2.166.Peer-Reviewed Original ResearchConceptsT cell-depleted miceMice treated with cyclophosphamideHemagglutination-inhibiting antibodiesBanzi virusViral antigensLethal infectionX-irradiated miceSublethal X-irradiationSpread of viral antigenGenetic resistanceTiters of virusDetectable hemagglutination-inhibition antibodyAverage survival timeT cellsImmunological factorsImmunosuppressed miceResistance to infectionLymphoid tissueCyclophosphamideSurvival timeMiceYield of virusMortality rateX-irradiationInfection