2013
Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals
St-Onge M, Wolfe S, Sy M, Shechter A, Hirsch J. Sleep restriction increases the neuronal response to unhealthy food in normal-weight individuals. International Journal Of Obesity 2013, 38: 411-416. PMID: 23779051, PMCID: PMC3883872, DOI: 10.1038/ijo.2013.114.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingFood stimuliRight insulaUnhealthy foodsUnhealthy food stimuliNormal-weight individualsMiddle temporal gyrusLevel-dependent activityInferior parietal lobuleSuperior frontal gyrusInsula activityFrontal gyrusGreater activationNeural mechanismsTemporal gyrusParietal lobuleFood intakeOrbitofrontal cortexRestricted sleepSame stimuliNeuronal responsesSleep restrictionNeural systemsBrain rewardShort sleep duration
2012
Conceptual representations of perceptual knowledge
Smith EE, Myers N, Sethi U, Pantazatos S, Yanagihara T, Hirsch J. Conceptual representations of perceptual knowledge. Cognitive Neuropsychology 2012, 29: 237-248. PMID: 22994286, PMCID: PMC3516296, DOI: 10.1080/02643294.2012.706218.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusFunctional magnetic resonance imagingFusiform gyrusPerceptual propertiesPerceptual knowledgeLeft inferior frontal gyrusLeft fusiform gyrusMiddle temporal gyrusPerceptual processingAmodal processesModality-specific mannerSemantic memoryBehavioral performanceFrontal gyrusThompson-SchillConceptual representationKan et alVerbal statementsGyrusParticipantsProcessingMagnetic resonance imagingRepresentationBarsalouMemoryNeural systems for speech and song in autism
Lai G, Pantazatos SP, Schneider H, Hirsch J. Neural systems for speech and song in autism. Brain 2012, 135: 961-975. PMID: 22298195, PMCID: PMC3286324, DOI: 10.1093/brain/awr335.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgingAnisotropyAttentionAutistic DisorderBrainChildDiffusion Tensor ImagingFemaleFunctional LateralityHead MovementsHumansImage Processing, Computer-AssistedInterview, PsychologicalLanguageMagnetic Resonance ImagingMaleMusicNerve NetNeural PathwaysNeuropsychological TestsPhotic StimulationRecruitment, NeurophysiologicalSpeechYoung AdultConceptsInferior frontal gyrusLeft inferior frontal gyrusFrontal gyrusAutistic childrenNeural systemsArcuate fasciculusFunctional magnetic resonanceSuperior temporal gyrusAge-matched control childrenLeft arcuate fasciculusPassive auditory stimulationMusic abilityLanguage disabilitySong conditionTemporal gyrusSpeech stimulationAuditory stimulationAutismFunctional connectivityNeural organizationBrain regionsSpeechControl childrenGyrusAutistic
2011
Neural response to eye contact and paroxetine treatment in generalized social anxiety disorder
Schneier FR, Pomplun M, Sy M, Hirsch J. Neural response to eye contact and paroxetine treatment in generalized social anxiety disorder. Psychiatry Research 2011, 194: 271-278. PMID: 22047726, PMCID: PMC3230304, DOI: 10.1016/j.pscychresns.2011.08.006.Peer-Reviewed Original ResearchConceptsParoxetine treatmentInferior parietal lobuleGeneralized social anxiety disorderNeural responsesPosterior cingulateParietal lobuleAnxiety disordersGSAD patientsEye contactMiddle occipital cortexMiddle frontal gyrusFunctional magnetic resonanceSymptomatic improvementHealthy comparison participantsOccipital cortexSocial anxiety disorderSymptom reductionAnterior cingulatePatientsUnmedicated adultsParahippocampal cortexNeural circuitrySupramarginal gyrusFrontal gyrusCingulateIncreased neuronal activity in response to food stimuli after periods of reduced sleep relative to habitual sleep in normal weight men and women
McReynolds A, Roberts A, Sy M, Hirsch J, St‐Onge M. Increased neuronal activity in response to food stimuli after periods of reduced sleep relative to habitual sleep in normal weight men and women. The FASEB Journal 2011, 25: 328.2-328.2. DOI: 10.1096/fasebj.25.1_supplement.328.2.Peer-Reviewed Original ResearchFood stimuliHabitual sleepCognitive control mechanismsNormal-weight menNon-food stimuliFunctional magnetic resonanceSleep durationSuperior frontal gyrusShort sleep conditionShort sleepImages of foodAnterior cingulate gyrusWeight menFrontal gyrusReward salienceBrain activityShort sleep durationSleep conditionsPrevalence of obesityCingulate gyrusReduced sleepStimuliH sleepSleepGyrus
2008
Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli
Rosenbaum M, Sy M, Pavlovich K, Leibel RL, Hirsch J. Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli. Journal Of Clinical Investigation 2008, 118: 2583-2591. PMID: 18568078, PMCID: PMC2430499, DOI: 10.1172/jci35055.Peer-Reviewed Original ResearchConceptsMiddle frontal gyrusNeural activityFood cuesFrontal gyrusFood-related visual cuesWeight lossFood intakeWeight loss-induced changesVisual food cuesVisual food stimuliMiddle temporal gyrusRelative leptin deficiencyWeight-reduced stateDaily subcutaneous injectionsBody weight maintenanceCognitive controlFood stimuliTemporal gyrusVisual cuesLeptin deficiencyObese subjectsWeight maintenanceLingual gyrusClinical managementFunctional MRI
2007
Mathematical and Linguistic Processing Differs Between Native and Second Languages: An fMRI Study
Wang Y, Lin L, Kuhl P, Hirsch J. Mathematical and Linguistic Processing Differs Between Native and Second Languages: An fMRI Study. Brain Imaging And Behavior 2007, 1: 68-82. DOI: 10.1007/s11682-007-9007-y.Peer-Reviewed Original ResearchMandarin Chinese learnersAdditional neural activationSecond languageNonnative languageChinese learnersL1 systemLinguistic tasksPhonetic discriminationPerisylvian language areasLanguage areasLanguageL2Specific neurocircuitryProcessing differsL1Neuro-mechanismEnglishInferior frontal gyrusLearnersNativesParity judgmentsLeft hemisphereJudgmentsFrontal gyrusFMRI studyCortical activation during word processing in late bilinguals: Similarities and differences as revealed by functional magnetic resonance imaging
Marian V, Shildkrot Y, Blumenfeld HK, Kaushanskaya M, Faroqi-Shah Y, Hirsch J. Cortical activation during word processing in late bilinguals: Similarities and differences as revealed by functional magnetic resonance imaging. Journal Of Clinical And Experimental Neuropsychology 2007, 29: 247-265. PMID: 17454346, DOI: 10.1080/13803390600659376.Peer-Reviewed Original ResearchMeSH KeywordsAcoustic StimulationAdolescentAdultCerebral CortexData Interpretation, StatisticalFemaleFrontal LobeFunctional LateralityHumansImage Processing, Computer-AssistedLanguage TestsMagnetic Resonance ImagingMaleMental ProcessesMultilingualismNerve NetOccipital LobeSpeech PerceptionTemporal LobeConceptsInferior frontal gyrusLeft inferior frontal gyrusFunctional magnetic resonance imagingLexical processingSuperior temporal gyrusSecond languageCenter of activationCortical activationRight inferior frontal gyrusRussian-English bilingualsCortical organizationSimilar cortical networksLate bilingualsTranslation equivalentsOrthographic processingPhonological processingSame languageWord processingInferior frontalFrontal gyrusSupramarginal gyrusLanguageDifferent wordsTemporal gyrusBilinguals
2006
A Neural Representation of Categorization Uncertainty in the Human Brain
Grinband J, Hirsch J, Ferrera VP. A Neural Representation of Categorization Uncertainty in the Human Brain. Neuron 2006, 49: 757-763. PMID: 16504950, DOI: 10.1016/j.neuron.2006.01.032.Peer-Reviewed Original ResearchConceptsCategorization uncertaintyEvent-related functional MRIFundamental cognitive functionFrontoparietal attention networkMedial frontal gyrusStimulus categorizationNeural representationParietal eye fieldsVisual objectsCategorical boundariesAnterior insulaFrontal gyrusCortical substratesAttention networkCognitive functionVentral striatumFunctional MRIPsychophysical functionsEye fieldBrain regionsHuman brainDorsomedial thalamusDiscrete categoriesInsulaThalamic network
2005
Discordance between functional magnetic resonance imaging during silent speech tasks and intraoperative speech arrest.
Petrovich N, Holodny AI, Tabar V, Correa DD, Hirsch J, Gutin PH, Brennan CW. Discordance between functional magnetic resonance imaging during silent speech tasks and intraoperative speech arrest. Journal Of Neurosurgery 2005, 103: 267-74. PMID: 16175856, DOI: 10.3171/jns.2005.103.2.0267.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusSpeech taskPrecentral gyrusFMR imaging activationFunctional magnetic resonanceSpeech arrestFMR imaging studiesFMR imagingBehavioral resultsAwake cortical mappingFrontal gyrusLanguage functionHemispheric dominanceNeurosurgical planningMotor stripIntraoperative indicatorAwake craniotomyCortical mappingIntraoperative mappingHealthy volunteersImaging activityControl studyPredominant activationImaging studiesGyrusVisual and Tactile Guidance of Dexterous Manipulation Tasks: An fMRI Study
Talati A, Valero-Cuevas FJ, Hirsch J. Visual and Tactile Guidance of Dexterous Manipulation Tasks: An fMRI Study. Perceptual And Motor Skills 2005, 101: 317-334. PMID: 16353365, DOI: 10.2466/pms.101.1.317-334.Peer-Reviewed Original ResearchConceptsModulation of activityTactile inputMedial frontal gyrusInferior parietal lobuleSensory informationMotor guidancePostcentral gyrusCingulate gyrusPrecentral gyrusSomatosensory inputFunctional magnetic resonance imagesNeural systemsParietal lobuleCerebellum activityMagnetic resonance imagesGyrusMotor tasksFrontal gyrusFMRI studyEyesResonance imagesExecutive functionSlender springVisual inputTactile informationThe neural correlates and functional integration of cognitive control in a Stroop task
Egner T, Hirsch J. The neural correlates and functional integration of cognitive control in a Stroop task. NeuroImage 2005, 24: 539-547. PMID: 15627596, DOI: 10.1016/j.neuroimage.2004.09.007.Peer-Reviewed Original ResearchConceptsCognitive controlConflict adaptationPsychophysiological interaction analysisStroop taskNeural correlatesFrontal gyrusPrefrontal cortexDistinct fronto-parietal networksEvent-related fMRI dataLow-conflict trialsHigh-conflict trialsFronto-parietal networkLateral prefrontal cortexMiddle frontal gyrusBilateral inferior frontalSuperior frontal gyrusContext-specific modulationInterference taskResponse conflictCognitive tasksConflict effectMotor processesInferior frontalNeural substratesTask performance
2003
fMRI Evidence for Cortical Modification during Learning of Mandarin Lexical Tone
Wang Y, Sereno JA, Jongman A, Hirsch J. fMRI Evidence for Cortical Modification during Learning of Mandarin Lexical Tone. Journal Of Cognitive Neuroscience 2003, 15: 1019-1027. PMID: 14614812, DOI: 10.1162/089892903770007407.Peer-Reviewed Original ResearchConceptsLanguage-related areasSecond languageBroca's areaEmergence of activityRight inferior frontal gyrusFunctional magnetic resonance imagingMandarin lexical tonesNative English speakersInferior frontal gyrusAdditional cortical regionsSupplementary motor regionsSuperior temporal gyrusBrodmann's area 42Area 42Lexical tonesEnglish speakersTone trainingFrontal gyrusLanguage functionTemporal gyrusWernicke's areaAuditory cortexMotor regionsCortical regionsLanguageShared and separate systems in bilingual language processing: Converging evidence from eyetracking and brain imaging
Marian V, Spivey M, Hirsch J. Shared and separate systems in bilingual language processing: Converging evidence from eyetracking and brain imaging. Brain And Language 2003, 86: 70-82. PMID: 12821416, DOI: 10.1016/s0093-934x(02)00535-7.Peer-Reviewed Original ResearchConceptsBilingual language processingLanguage processingLeft inferior frontal gyrusRussian-English bilingualsSecond language processingInferior frontal gyrusFunctional neuroimaging studiesLevel of processingSuperior temporal gyrusLinguistic inputWord recognitionCognitive aspectsFrontal gyrusFunctional neuroimagingNeuroimaging studiesLanguageTemporal gyrusEyetracking studyBilingualsBrain imagingCortical structuresParallel activationEyetrackingGyrusProcessing
2001
Interconnected Large-Scale Systems for Three Fundamental Cognitive Tasks Revealed by Functional MRI
Hirsch J, Moreno D, Kim K. Interconnected Large-Scale Systems for Three Fundamental Cognitive Tasks Revealed by Functional MRI. Journal Of Cognitive Neuroscience 2001, 13: 389-405. PMID: 11371315, DOI: 10.1162/08989290151137421.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusMedial frontal gyrusFunctional magnetic resonance imagingRight precentral gyrusFrontal gyrusInferior parietal lobuleNeurocognitive systemsBA 6Brain areasPrecentral gyrusParietal lobuleArea 45Left inferior frontal gyrusWhole-brain functional magnetic resonance imagingBA 40Fundamental cognitive tasksRight inferior parietal lobuleCortical regionsSame-different discriminationLeft medial frontal gyrusMultiple sensory modalitiesBrodmann area 45Superior temporal gyrusMiddle frontal gyrusPrimary sensory processes