2022
The Species-Specific 282 Residue in the PB2 Subunit of the Polymerase Regulates RNA Synthesis and Replication of Influenza A Viruses Infecting Bat and Nonbat Hosts
Banerjee S, De A, Kedia N, Bhakta K, Wang L, Bhattacharjee B, Mondal A. The Species-Specific 282 Residue in the PB2 Subunit of the Polymerase Regulates RNA Synthesis and Replication of Influenza A Viruses Infecting Bat and Nonbat Hosts. Journal Of Virology 2022, 96: e02190-21. PMID: 35044213, PMCID: PMC8906409, DOI: 10.1128/jvi.02190-21.Peer-Reviewed Original ResearchConceptsBat influenza virusesInfluenza virus polymeraseInfluenza A virusVirus polymerasePB2 subunitIAV RNA polymeraseGenera of influenza virusesHost speciesAdaptation of influenza virusesInfluenza virusHuman cellsPolymerase subunit PB2RNA synthesis activitySpecies-specific signaturesHuman-specific signaturesAmino acid preferencesReduced polymerase activityAmino acid alterationsGlutamic acidA virusSurface antigen hemagglutininCross-species transmissionRNA polymerasePB2 proteinSignature residues
2012
Genetic Analysis of Cytomegalovirus in Malignant Gliomas
Bhattacharjee B, Renzette N, Kowalik T. Genetic Analysis of Cytomegalovirus in Malignant Gliomas. Journal Of Virology 2012, 86: 6815-6824. PMID: 22496213, PMCID: PMC3393585, DOI: 10.1128/jvi.00015-12.Peer-Reviewed Original ResearchConceptsDNA copy numberViral DNA copy numberPresence of intact open reading framesCopy numberLong regionMalignant gliomasHigh amino acid sequence conservationAmino acid sequence conservationIntact open reading framesViral populationsHuman cytomegalovirusOpen reading frameAmino acid changesSingle gene productsGenome coverageGlioblastoma multiformeSequence conservationReading framePhylogenetic analysisHCMV prevalenceCore genesSequence analysisShort regionLow-grade tumorsGenetic analysis