2023
Metformin prescription for U.S. veterans with prediabetes, 2010–2019
Gulanski B, Goulet J, Radhakrishnan K, Ko J, Li Y, Rajeevan N, Lee K, Heberer K, Lynch J, Streja E, Mutalik P, Cheung K, Concato J, Shih M, Lee J, Aslan M. Metformin prescription for U.S. veterans with prediabetes, 2010–2019. Journal Of Investigative Medicine 2023, 72: 139-150. PMID: 37668313, DOI: 10.1177/10815589231201141.Peer-Reviewed Original ResearchConceptsBody mass indexVeterans Health AdministrationIncident prediabetesHigh riskHealth AdministrationRetrospective observational cohort studyType 2 diabetes mellitusUse of metforminObservational cohort studyProportion of veteransMetformin prescribingGestational diabetesCohort studyMetformin prescriptionDiabetes mellitusDiabetes preventionMass indexCardiovascular diseaseMultivariable modelPrediabetesSubset of individualsMetforminU.S. veteransHealthcare systemVeteransEffectiveness of COVID-19 Treatment With Nirmatrelvir–Ritonavir or Molnupiravir Among U.S. Veterans: Target Trial Emulation Studies With One-Month and Six-Month Outcomes
Bajema K, Berry K, Streja E, Rajeevan N, Li Y, Mutalik P, Yan L, Cunningham F, Hynes D, Rowneki M, Bohnert A, Boyko E, Iwashyna T, Maciejewski M, Osborne T, Viglianti E, Aslan M, Huang G, Ioannou G. Effectiveness of COVID-19 Treatment With Nirmatrelvir–Ritonavir or Molnupiravir Among U.S. Veterans: Target Trial Emulation Studies With One-Month and Six-Month Outcomes. Annals Of Internal Medicine 2023, 176: m22-3565. PMID: 37276589, PMCID: PMC10243488, DOI: 10.7326/m22-3565.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationCOVID-19 symptom onsetCOVID-19-related outcomesSevere COVID-19Six-month outcomesCOVID-19 vaccinationCOVID-19 treatmentCOVID-19SARS-CoV-2Percent of participantsUntreated control participantsCause mortalitySymptom onsetMedian ageOral antiviralsVHA careOutpatient treatmentHospitalizationHealth AdministrationDay 31U.S. veteransVariant transmissionMost veteransVeterans AffairsOne month
2008
P1‐141: Modeling the “dendritic hypothesis” of Alzheimer pathogenesis: A neuroinformatics approach for elucidating part of the amyloid beta cascade
Morse T, Mutalik P, Cheung K, Miller P, Shepherd G. P1‐141: Modeling the “dendritic hypothesis” of Alzheimer pathogenesis: A neuroinformatics approach for elucidating part of the amyloid beta cascade. Alzheimer's & Dementia 2008, 4: t248-t248. DOI: 10.1016/j.jalz.2008.05.728.Peer-Reviewed Original Research
2003
Longitudinal Evaluation of Apparent Diffusion Coefficient in Children with Neurofibromatosis Type 1
Sheikh S, Kubal W, Anderson A, Mutalik P. Longitudinal Evaluation of Apparent Diffusion Coefficient in Children with Neurofibromatosis Type 1. Journal Of Computer Assisted Tomography 2003, 27: 681-686. PMID: 14501358, DOI: 10.1097/00004728-200309000-00004.Peer-Reviewed Original ResearchConceptsInfratentorial lesionsApparent diffusion coefficientPatient agePediatric patientsSupratentorial lesionsADC of lesionsMm2 xNF1 lesionsComparison groupNeurofibromatosis type 1 patientsType 1 patientsNeurofibromatosis type 1Diffusion-weighted imagingMyelin vacuolesInfratentorial brainIntracranial lesionsNormal subjectsNormal brainSimilar lesionsLinear regression analysisLesionsLongitudinal evaluationType 1PatientsNormal children
2001
Use of General-purpose Negation Detection to Augment Concept Indexing of Medical Documents
Mutalik P, Deshpande A, Nadkarni P. Use of General-purpose Negation Detection to Augment Concept Indexing of Medical Documents. Journal Of The American Medical Informatics Association 2001, 8: 598-609. PMID: 11687566, PMCID: PMC130070, DOI: 10.1136/jamia.2001.0080598.Peer-Reviewed Original ResearchConceptsNegation detectionMedical documentsUMLS conceptsProgramming language compilersFinite state machinesLanguage compilerConcept indexingMedical narrativesContext-free grammarsConcept matchingLexical scannerAbsence of negationDifferent test setsFormal languageState machinesRegular expressionsReliability of detectionDiverse training setConcept IDsTraining setParserHuman observationTest setLarge setHuman observers
1998
Voice-activated retrieval of mammography reference images
Swett H, Mutalik P, Neklesa V, Horvath L, Lee C, Richter J, Tocino I, Fisher P. Voice-activated retrieval of mammography reference images. Journal Of Digital Imaging 1998, 11: 65. PMID: 9608929, PMCID: PMC3452994, DOI: 10.1007/bf03168728.Peer-Reviewed Original ResearchConceptsFurther system developmentImage databaseReference imageImage setsSystem developmentDigital mammography imagesImage retrievalImage featuresVoice dictationRadiology reporting systemSearch resultsAutomatic retrievalMammography imagesAutomatic methodRetrievalImage interpretationImagesSearch strategyMammographic casesDatabase search strategySetSystem outputDatabase search termsLarge numberReporting process
1996
The RFI (request for information) as a tool to identify an optimal departmental and institutional PACS
Mutalik P, Neklesa V, Swett H. The RFI (request for information) as a tool to identify an optimal departmental and institutional PACS. 1996, 66-70. DOI: 10.1109/imac.1995.532562.Peer-Reviewed Original Research
1995
Tomographic Studies of Human Jaws to Assess Potentials for Preserving the Blood Supply in Rim Mandibulectomies
Ariyan S, Abrahams J, Brattelbort S, Mutalik P. Tomographic Studies of Human Jaws to Assess Potentials for Preserving the Blood Supply in Rim Mandibulectomies. Plastic & Reconstructive Surgery 1995, 96: 816-822. PMID: 7652055, DOI: 10.1097/00006534-199509001-00008.Peer-Reviewed Original ResearchTomographic Studies of Human Jaws to Assess Potentials for Preserving the Blood Supply in Rim Mandibulectomies
Ariyan S, Abrahams J, Brattelbort S, Mutalik P, Shah J. Tomographic Studies of Human Jaws to Assess Potentials for Preserving the Blood Supply in Rim Mandibulectomies. Plastic & Reconstructive Surgery 1995, 96: 823-824. DOI: 10.1097/00006534-199509001-00009.Peer-Reviewed Original Research
1991
The prospect of expert system—Based cognitive support as a by-product of image acquisition and reporting
Mutalik P, Weltin G, Fisher P, Swett H. The prospect of expert system—Based cognitive support as a by-product of image acquisition and reporting. Journal Of Digital Imaging 1991, 4: 233-240. PMID: 1772916, DOI: 10.1007/bf03173905.Peer-Reviewed Original ResearchConceptsDecision supportComputer-based decision support toolDomain of mammographyImage acquisitionComputer interactionUser interfaceDecision support toolExpert systemAutomatic fashionKnowledge contentCognitive supportContent-related questionsInformal evaluationClinical radiologyCase informationInterfaceUsersComputerInterface modelSystemAcquisitionWork patternsInformationSupportToolExpert System Advice as a By-Product of Image Acquisition and Reporting: Obstacles to be Overcome
Mutalik P, Fisher P, Weltin G, Swett H. Expert System Advice as a By-Product of Image Acquisition and Reporting: Obstacles to be Overcome. 1991, 315-320. DOI: 10.1007/978-3-662-00807-2_52.Peer-Reviewed Original ResearchComputer interactionExpert systemIntelligent decision supportImage acquisitionStrengths of computersRadiology information systemExpert system adviceComputer-based expert systemUse of computersImage archivingComputer systemsExpert system consultationsPrototype systemDecision supportInformation systemsSystem adviceComputerDiagnostic adviceActual cognitive processesRadiological imagesRadiology todayLong-term goalArchivingSystemImages
1990
Knowledge-based radiologic image retrieval using axes of clinical relevance
Cohn A, Miller P, Fisher P, Mutalik P, Swett H. Knowledge-based radiologic image retrieval using axes of clinical relevance. Journal Of Biomedical Informatics 1990, 23: 199-221. PMID: 2350958, DOI: 10.1016/0010-4809(90)90017-7.Peer-Reviewed Original ResearchConceptsPrototype knowledge-based systemKnowledge-based systemIntelligent retrievalImage retrievalDomain knowledgeSearch spaceSearch processUser groupsSearch constraintsHeuristicsRetrievalSearch strategyImagesClinicians' needsRadiographic imagesSearchProbable relevanceSystemDomainConstraintsSpecific caseAttributesPreliminary testsKnowledgeNeed
1989
Expert system-controlled image display.
Swett H, Fisher P, Cohn A, Miller P, Mutalik P. Expert system-controlled image display. Radiology 1989, 172: 487-93. PMID: 2664871, DOI: 10.1148/radiology.172.2.2664871.Peer-Reviewed Original ResearchConceptsMedical expert systemsGroup of imagesExpert computer systemGroups of featuresComputer systemsPattern recognitionExpert systemPicture archivingCommunication systemsSeries of axesKey featuresArchivingWorkstationsSubtle morphologic featuresFeaturesSystemIconsImagesRecognitionDifferent waysDiagnostic radiologyTextToolDecisions
1987
Naloxone paradoxically facilitates stimulation-produced analgesia (SPA) from monkey periaqueductal gray (PAG)
Mutalik P, Alreja M. Naloxone paradoxically facilitates stimulation-produced analgesia (SPA) from monkey periaqueductal gray (PAG). Pain 1987, 30: s289. DOI: 10.1016/0304-3959(87)91639-3.Peer-Reviewed Original ResearchA comparison of the analgesic effect of periaqueductal gray (PAG) stimulation on ‘PHASIC’ and ‘TONIC’ pain in rhesus monkeys
Alreja M, Mutalik P. A comparison of the analgesic effect of periaqueductal gray (PAG) stimulation on ‘PHASIC’ and ‘TONIC’ pain in rhesus monkeys. Pain 1987, 30: s289. DOI: 10.1016/0304-3959(87)91638-1.Peer-Reviewed Original Research
1985
Behavioral scoring using programmable calculators: A technique usable in the field
Mutalik P, Alreja M, Nayar U. Behavioral scoring using programmable calculators: A technique usable in the field. Physiology & Behavior 1985, 35: 831-833. PMID: 3841218, DOI: 10.1016/0031-9384(85)90420-2.Peer-Reviewed Original Research
1984
The formalin test: A tonic pain model in the primate
Alreja M, Mutalik P, Nayar U, Manchanda S. The formalin test: A tonic pain model in the primate. Pain 1984, 20: 97-105. PMID: 6493793, DOI: 10.1016/0304-3959(84)90815-7.Peer-Reviewed Original Research