2020
EXpectation Propagation LOgistic REgRession on permissioned blockCHAIN (ExplorerChain): decentralized online healthcare/genomics predictive model learning
Kuo T, Gabriel R, Cidambi K, Ohno-Machado L. EXpectation Propagation LOgistic REgRession on permissioned blockCHAIN (ExplorerChain): decentralized online healthcare/genomics predictive model learning. Journal Of The American Medical Informatics Association 2020, 27: 747-756. PMID: 32364235, PMCID: PMC7309256, DOI: 10.1093/jamia/ocaa023.Peer-Reviewed Original ResearchConceptsBlockchain technologyCentral serverServer-based methodBenefits of blockchainData protection policiesCentralized serverArtificial intelligenceModel learningDecentralized approachSmall datasetsBlockchainServerComputation strategySingle pointGeneralizable modelCost of efficiencyGenomic datasetsDatasetDistributed modelTechnologyGenomic dataMultiple institutionsDiscrimination powerIntelligencePotential advantages/disadvantages
2019
Fair compute loads enabled by blockchain: sharing models by alternating client and server roles
Kuo T, Gabriel R, Ohno-Machado L. Fair compute loads enabled by blockchain: sharing models by alternating client and server roles. Journal Of The American Medical Informatics Association 2019, 26: 392-403. PMID: 30892656, PMCID: PMC7787356, DOI: 10.1093/jamia/ocy180.Peer-Reviewed Original Research
2018
Clinical informatics applications of medication reconciliation, decision support systems, and online portal patient-provider communications
Ohno-Machado L. Clinical informatics applications of medication reconciliation, decision support systems, and online portal patient-provider communications. Journal Of The American Medical Informatics Association 2018, 25: 1431-1431. PMID: 30380084, PMCID: PMC7646928, DOI: 10.1093/jamia/ocy150.Commentaries, Editorials and LettersMeSH KeywordsDecision Support Systems, ClinicalElectronic Health RecordsHumansMedication ReconciliationPatient Portals
2017
Integrated precision medicine: the role of electronic health records in delivering personalized treatment
Sitapati A, Kim H, Berkovich B, Marmor R, Singh S, El‐Kareh R, Clay B, Ohno‐Machado L. Integrated precision medicine: the role of electronic health records in delivering personalized treatment. WIREs Mechanisms Of Disease 2017, 9 PMID: 28207198, PMCID: PMC5400726, DOI: 10.1002/wsbm.1378.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsDecision Support Systems, ClinicalDelivery of Health Care, IntegratedElectronic Health RecordsHealth Information ExchangeHumansPrecision Medicine
2016
Using health information technology for clinical decision support and predictive analytics
Ohno-Machado L. Using health information technology for clinical decision support and predictive analytics. Journal Of The American Medical Informatics Association 2016, 24: 1-1. PMID: 28039394, PMCID: PMC7654091, DOI: 10.1093/jamia/ocw163.Commentaries, Editorials and LettersDecision Support Systems, ClinicalHealth Information ManagementInformation TechnologyMedical InformaticsData and the clinical decision support loop
Ohno-Machado L, Editor-in-Chief. Data and the clinical decision support loop. Journal Of The American Medical Informatics Association 2016, 23: e1-e1. PMID: 27071919, PMCID: PMC4954618, DOI: 10.1093/jamia/ocw060.Commentaries, Editorials and LettersData CollectionDatabases, FactualDecision Support Systems, ClinicalHumansQuality Assurance, Health Care
2015
WebDISCO: a web service for distributed cox model learning without patient-level data sharing
Lu C, Wang S, Ji Z, Wu Y, Xiong L, Jiang X, Ohno-Machado L. WebDISCO: a web service for distributed cox model learning without patient-level data sharing. Journal Of The American Medical Informatics Association 2015, 22: 1212-1219. PMID: 26159465, PMCID: PMC5009917, DOI: 10.1093/jamia/ocv083.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsComputer Communication NetworksDatasets as TopicDecision Support Systems, ClinicalHumansInformation DisseminationInternetProportional Hazards ModelsSurvival Analysis
2014
Focusing on the patient: mHealth, social media, electronic health records, and decision support systems
Ohno-Machado L. Focusing on the patient: mHealth, social media, electronic health records, and decision support systems. Journal Of The American Medical Informatics Association 2014, 21: 953-953. PMID: 25301806, PMCID: PMC4215063, DOI: 10.1136/amiajnl-2014-003341.Commentaries, Editorials and LettersHealth IT and clinical decision support systems: human factors and successful adoption
Ohno-Machado L. Health IT and clinical decision support systems: human factors and successful adoption. Journal Of The American Medical Informatics Association 2014, 21: e180-e180. PMID: 25200586, PMCID: PMC4173189, DOI: 10.1136/amiajnl-2014-003279.Peer-Reviewed Original Research“Big Data” and the Electronic Health Record
Ross M, Wei W, Ohno-Machado L. “Big Data” and the Electronic Health Record. Yearbook Of Medical Informatics 2014, 23: 97-104. PMID: 25123728, PMCID: PMC4287068, DOI: 10.15265/iy-2014-0003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsComputational BiologyData MiningDecision Support Systems, ClinicalElectronic Health RecordsMedical Records Systems, ComputerizedNatural Language ProcessingPharmacovigilanceSocial MediaConceptsBig dataEHR systemsElectronic health record systemsHealth record systemsData miningElectronic health recordsData applicationsActionable knowledgeMassive numberAdditional keywordsNew keywordsSecondary useInformatics professionalsHealth recordsRecord systemKeywordsLarge amountPrivacyNext stepMiningSecurityEHRSystemImplementationDataElectronic health record systems: risks and benefits
Ohno-Machado L. Electronic health record systems: risks and benefits. Journal Of The American Medical Informatics Association 2014, 21: e1-e1. PMID: 24453123, PMCID: PMC3957407, DOI: 10.1136/amiajnl-2014-002635.Commentaries, Editorials and LettersDecision Support Systems, ClinicalElectronic Health RecordsHumansMedical Records Systems, ComputerizedPatient Safety
2011
Informatics is about algorithms, systems, people, and social networks
Ohno-Machado L. Informatics is about algorithms, systems, people, and social networks. Journal Of The American Medical Informatics Association 2011, 18: 209-209. PMID: 21486878, PMCID: PMC3078672, DOI: 10.1136/amiajnl-2011-000266.Commentaries, Editorials and LettersWhat's new in informatics
Ohno-Machado L. What's new in informatics. Journal Of The American Medical Informatics Association 2011, 18: 1-1. PMID: 21169616, PMCID: PMC3005884, DOI: 10.1136/jamia.2010.009910.Commentaries, Editorials and LettersConfidentialityDecision Support Systems, ClinicalDocumentationElectronic Health RecordsHumansInformation Systems
2006
PROGNOSIS IN CRITICAL CARE
Ohno-Machado L, Resnic F, Matheny M. PROGNOSIS IN CRITICAL CARE. Annual Review Of Biomedical Engineering 2006, 8: 567-599. PMID: 16834567, DOI: 10.1146/annurev.bioeng.8.061505.095842.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsArtificial IntelligenceCritical CareDecision Support Systems, ClinicalDiagnosis, Computer-AssistedHealth Status IndicatorsHumansPrognosisProportional Hazards ModelsRisk AssessmentRisk Factors
2005
Discrimination and calibration of mortality risk prediction models in interventional cardiology
Matheny M, Ohno-Machado L, Resnic F. Discrimination and calibration of mortality risk prediction models in interventional cardiology. Journal Of Biomedical Informatics 2005, 38: 367-375. PMID: 16198996, DOI: 10.1016/j.jbi.2005.02.007.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryCalibrationCardiologyComorbidityDecision Support Systems, ClinicalDiagnosis, Computer-AssistedDiscriminant AnalysisExpert SystemsHumansIncidenceOutcome Assessment, Health CarePostoperative ComplicationsPrognosisRetrospective StudiesRisk AssessmentRisk FactorsROC CurveSurvival AnalysisSurvival RateUnited StatesConceptsLocal risk modelAcute myocardial infarctionHosmer-Lemeshow goodnessRisk prediction modelRisk factorsCardiology-National Cardiovascular Data RegistryConsecutive percutaneous coronary interventionsMortality risk prediction modelPercutaneous coronary interventionMultivariate risk factorsCertain risk factorsROC curveAccurate risk predictionIndividual casesGood discriminationCardiogenic shockHospital mortalityCoronary interventionUnstable anginaArtery interventionPatient populationMyocardial infarctionRisk modelElective proceduresWomen's HospitalA global goodness-of-fit test for receiver operating characteristic curve analysis via the bootstrap method
Zou K, Resnic F, Talos I, Goldberg-Zimring D, Bhagwat J, Haker S, Kikinis R, Jolesz F, Ohno-Machado L. A global goodness-of-fit test for receiver operating characteristic curve analysis via the bootstrap method. Journal Of Biomedical Informatics 2005, 38: 395-403. PMID: 16198998, DOI: 10.1016/j.jbi.2005.02.004.Peer-Reviewed Original ResearchAdolescentAdultAlgorithmsAngioplasty, Balloon, CoronaryBrain NeoplasmsCalibrationData Interpretation, StatisticalDecision Support Systems, ClinicalDiagnosis, Computer-AssistedDiscriminant AnalysisExpert SystemsFemaleHumansIncidenceMaleMiddle AgedOutcome Assessment, Health CarePrognosisRisk AssessmentRisk FactorsROC CurveSurvival AnalysisSurvival RateUnited States
2002
Providing context-sensitive decision-support based on WHO guidelines.
Ray H, Boxwala A, Anantraman V, Ohno-Machado L. Providing context-sensitive decision-support based on WHO guidelines. AMIA Annual Symposium Proceedings 2002, 637-41. PMID: 12463901, PMCID: PMC2244156.Peer-Reviewed Original Research
2001
Using patient-reportable clinical history factors to predict myocardial infarction
Wang S, Ohno-Machado L, Fraser H, Kennedy R. Using patient-reportable clinical history factors to predict myocardial infarction. Computers In Biology And Medicine 2001, 31: 1-13. PMID: 11058690, DOI: 10.1016/s0010-4825(00)00022-6.Peer-Reviewed Original ResearchGeneration of dynamically configured check lists for intra-operative problems using a set of covering algorithms.
Sawa T, Ohno-Machado L. Generation of dynamically configured check lists for intra-operative problems using a set of covering algorithms. AMIA Annual Symposium Proceedings 2001, 593-7. PMID: 11837218, PMCID: PMC2243696.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAnesthesiologyDecision Support Systems, ClinicalEquipment FailureHumansIntraoperative ComplicationsMonitoring, Intraoperative
1999
The decision systems group: creating a framework for decision making.
Greenes R, Boxwala A, Ohno-Machado L. The decision systems group: creating a framework for decision making. M.D. Computing 1999, 16: 23-7. PMID: 10507232.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsBostonDecision Support Systems, ClinicalDecision Support TechniquesDiagnosis, Computer-AssistedHumansMedical InformaticsNeeds AssessmentPractice Guidelines as TopicProblem SolvingResearchTherapy, Computer-Assisted