2021
Ultrafast homomorphic encryption models enable secure outsourcing of genotype imputation
Kim M, Harmanci A, Bossuat J, Carpov S, Cheon J, Chillotti I, Cho W, Froelicher D, Gama N, Georgieva M, Hong S, Hubaux J, Kim D, Lauter K, Ma Y, Ohno-Machado L, Sofia H, Son Y, Song Y, Troncoso-Pastoriza J, Jiang X. Ultrafast homomorphic encryption models enable secure outsourcing of genotype imputation. Cell Systems 2021, 12: 1108-1120.e4. PMID: 34464590, PMCID: PMC9898842, DOI: 10.1016/j.cels.2021.07.010.Peer-Reviewed Original ResearchConceptsHomomorphic encryption techniqueResource-intensive computationsSecure outsourcingGenomic data analysisData securityEncryption modelEncryption techniquePrivacy concernsSource codeMemory requirementsGenetic data analysisData analysisComparable accuracyFundamental stepGenotype imputationImputationDownloadSecurityOutsourcingComputationCodeServicesRequirementsAccuracyMethod
2020
The Data Tags Suite (DATS) model for discovering data access and use requirements
Alter G, Gonzalez-Beltran A, Ohno-Machado L, Rocca-Serra P. The Data Tags Suite (DATS) model for discovering data access and use requirements. GigaScience 2020, 9: giz165. PMID: 32031623, PMCID: PMC7006671, DOI: 10.1093/gigascience/giz165.Peer-Reviewed Original ResearchConceptsData accessData discovery toolsPrivacy of subjectsData use agreementsConfidential dataMetadata itemsData reuseMetadata schemaAutomated systemDiscovery toolTechnical systemsStandard wayUse agreementsAccessPrivacyMetadataSchemaUse requirementsReuseResearchersResearch dataSystemRequirementsInformationData
2019
Comparison of blockchain platforms: a systematic review and healthcare examples
Kuo T, Rojas H, Ohno-Machado L. Comparison of blockchain platforms: a systematic review and healthcare examples. Journal Of The American Medical Informatics Association 2019, 26: 462-478. PMID: 30907419, PMCID: PMC7787359, DOI: 10.1093/jamia/ocy185.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBlockchain platformPopular blockchain platformsBlockchain applicationsSuitable blockchain platformDifferent blockchain platformsClinical informatics researchersTechnical featuresSoftware engineersHealth informatics applicationsHealthcare applicationsInformatics applicationsHealthcare exampleInformatics researchersPlatformBiomedical research applicationsHealthcareBlockchainImportant technical featuresKey featuresApplicationsResearch applicationsFeaturesBrief introductionTechnologyRequirements
2013
Data governance requirements for distributed clinical research networks: triangulating perspectives of diverse stakeholders
Kim K, Browe D, Logan H, Holm R, Hack L, Ohno-Machado L. Data governance requirements for distributed clinical research networks: triangulating perspectives of diverse stakeholders. Journal Of The American Medical Informatics Association 2013, 21: 714-719. PMID: 24302285, PMCID: PMC4078279, DOI: 10.1136/amiajnl-2013-002308.Peer-Reviewed Original ResearchConceptsFair Information Practice PrinciplesTechnical infrastructureClinical data reuseGovernance requirementsTrustworthy platformData reuseHealth Insurance PortabilityHIPAA regulationsAccountability ActNetworkInsurance PortabilityHealth informationRequirementsInformationResearch NetworkPrivacyPortabilityBest practicesInfrastructurePlatformReuseDiverse stakeholdersTimeliness