2016
PRINCESS: Privacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS
Chen F, Wang S, Jiang X, Ding S, Lu Y, Kim J, Sahinalp S, Shimizu C, Burns J, Wright V, Png E, Hibberd M, Lloyd D, Yang H, Telenti A, Bloss C, Fox D, Lauter K, Ohno-Machado L. PRINCESS: Privacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS. Bioinformatics 2016, 33: 871-878. PMID: 28065902, PMCID: PMC5860394, DOI: 10.1093/bioinformatics/btw758.Peer-Reviewed Original ResearchConceptsSoftware Guard ExtensionsHomomorphic encryptionDistributed ComputationCollaboration frameworkTrustworthy computationCollaboration modelSupplementary dataNetwork collaborationEncryptionExperimental resultsHealth informationAlternative solutionComputationInternational collaboration frameworkHardwareAccurate analysisPerformanceBioinformaticsImplementationFrameworkDataExtensionInformationCollaboration
2014
“Big Data” and the Electronic Health Record
Ross M, Wei W, Ohno-Machado L. “Big Data” and the Electronic Health Record. Yearbook Of Medical Informatics 2014, 23: 97-104. PMID: 25123728, PMCID: PMC4287068, DOI: 10.15265/iy-2014-0003.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBig dataEHR systemsElectronic health record systemsHealth record systemsData miningElectronic health recordsData applicationsActionable knowledgeMassive numberAdditional keywordsNew keywordsSecondary useInformatics professionalsHealth recordsRecord systemKeywordsLarge amountPrivacyNext stepMiningSecurityEHRSystemImplementationData
2011
Quantifying fine-grained privacy risk and representativeness in medical data
Jiang X, Cheng S, Ohno-Machado L. Quantifying fine-grained privacy risk and representativeness in medical data. 2011, 64-67. DOI: 10.1145/2023582.2023594.Peer-Reviewed Original Research
2004
Multivariate selection of genetic markers in diagnostic classification
Weber G, Vinterbo S, Ohno-Machado L. Multivariate selection of genetic markers in diagnostic classification. Artificial Intelligence In Medicine 2004, 31: 155-167. PMID: 15219292, DOI: 10.1016/j.artmed.2004.01.011.Peer-Reviewed Original ResearchConceptsClassification performanceBetter classification performanceLogistic regression algorithmUser-friendly implementationDifferent data setsSophisticated algorithmsRegression algorithmAlgorithmNew algorithmParticular classificationUnivariate algorithmsData setsGene expression dataClassificationNumber of variablesGene selectionSetInternetExpression dataNew setViable choiceMachinePerformanceImplementationSelection
1999
A framework and tools for authoring, editing, documenting, sharing, searching, navigating, and executing computer-based clinical guidelines.
Greenes R, Boxwala A, Sloan W, Ohno-Machado L, Deibel S. A framework and tools for authoring, editing, documenting, sharing, searching, navigating, and executing computer-based clinical guidelines. AMIA Annual Symposium Proceedings 1999, 261-5. PMID: 10566361, PMCID: PMC2232593.Peer-Reviewed Original ResearchConceptsComputer-based clinical guidelineInterMed CollaboratoryAutomatic executionSoftware toolsGuideline representationDelivery networkInternet distributionSharingSpecificationXMLFrameworkGLIFNavigationExecutionCollaboratoryToolNetworkImplementationRepresentationSuiteEditingEligibility determinationDocumenting