2022
Simplified Machine Learning Models Can Accurately Identify High-Need High-Cost Patients With Inflammatory Bowel Disease
Nguyen N, Patel S, Gabunilas J, Qian A, Cecil A, Jairath V, Sandborn W, Ohno-Machado L, Chen P, Singh S. Simplified Machine Learning Models Can Accurately Identify High-Need High-Cost Patients With Inflammatory Bowel Disease. Clinical And Translational Gastroenterology 2022, 13: e00507. PMID: 35905414, PMCID: PMC10476830, DOI: 10.14309/ctg.0000000000000507.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseUnplanned healthcare utilizationAdult patientsBowel diseaseHealthcare utilizationHealthcare costsLogistic regressionRetrospective cohort studyNationwide Readmissions DatabaseIdentification of patientsAdministrative claims dataHigh-cost patientsHNHC patientsCohort studyHospitalized patientsClaims dataHigh riskPatientsTraditional logistic regressionDerivation dataMean AUCIBDMean areaCharacteristic curveDisease
2020
Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases
Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases. Clinical Gastroenterology And Hepatology 2020, 19: 1377-1386.e5. PMID: 32526341, PMCID: PMC7987215, DOI: 10.1016/j.cgh.2020.05.056.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseEmergency department useCost-related medicationFinancial toxicityBowel diseaseHealthcare useDepartment useSocial supportMedical billsInadequate social supportMultivariable analysisFood insecurityHigh financial toxicityPatientsFinancial hardshipSocial determinantsAbstractTextPopulation healthPrevalenceHealthcare deliveryMedicationsAdultsDiseaseFamily incomeToxicity
2018
A Novel Stakeholder Engagement Approach for Patient-centered Outcomes Research
Kim K, Khodyakov D, Marie K, Taras H, Meeker D, Campos H, Ohno-Machado L. A Novel Stakeholder Engagement Approach for Patient-centered Outcomes Research. Medical Care 2018, 56: s41-s47. PMID: 30074950, PMCID: PMC6143220, DOI: 10.1097/mlr.0000000000000790.Peer-Reviewed Original ResearchConceptsClinical Data Research NetworkPatient-centered outcomes researchEngagement of patientsOutcomes research studiesConditions of focusStakeholder advisory boardPatient-centered outcomes research studiesKawasaki diseaseHeart failurePatient advocatesPatientsClinical sitesOutcomes researchSignificant differencesHealth researchCliniciansResearch NetworkResearch prioritiesSetting of prioritiesEngagement strategiesAdvisory BoardFavorable opinionObesityEngagement principlesDiseaseSu1886 - Burden of Hospitalization and Predictors of High Healthcare Utilization in Patients with Inflammatory Bowel Diseases in the United States
Nguyen N, Ohno-Machado L, Sandborn W, Singh S. Su1886 - Burden of Hospitalization and Predictors of High Healthcare Utilization in Patients with Inflammatory Bowel Diseases in the United States. Gastroenterology 2018, 154: s-620. DOI: 10.1016/s0016-5085(18)32232-7.Peer-Reviewed Original ResearchInfections and Cardiovascular Complications are Common Causes for Hospitalization in Older Patients with Inflammatory Bowel Diseases
Nguyen N, Ohno-Machado L, Sandborn W, Singh S. Infections and Cardiovascular Complications are Common Causes for Hospitalization in Older Patients with Inflammatory Bowel Diseases. Inflammatory Bowel Diseases 2018, 24: 916-923. PMID: 29562273, DOI: 10.1093/ibd/izx089.Peer-Reviewed Original ResearchConceptsInflammatory bowel diseaseOlder patientsYounger patientsAnnual burdenNationwide Readmissions Database 2013Treatment-related complicationsDisease-related complicationsCause of hospitalizationRepresentative cohort studyCohort studyBowel diseaseHigh riskPatientsMore daysHospitalizationComplicationsBurdenCauseRehospitalizationHospitalTherapyCohortPrevalenceDisease
2017
Burden, Costs and Causes for Hospitalization in Older Patients With Inflammatory Bowel Diseases: A Nationally Representative Cohort Study
Nguyen N, Ohno-Machado L, Sandborn W, Singh S. Burden, Costs and Causes for Hospitalization in Older Patients With Inflammatory Bowel Diseases: A Nationally Representative Cohort Study. The American Journal Of Gastroenterology 2017, 112: s345. DOI: 10.14309/00000434-201710001-00628.Peer-Reviewed Original ResearchObesity Is Associated With Higher Annual Burden and Costs of Hospitalization in Patients With Inflammatory Bowel Diseases: A Nationally Representative Cohort Study
Nguyen N, Ohno-Machado L, Sandborn W, Singh S. Obesity Is Associated With Higher Annual Burden and Costs of Hospitalization in Patients With Inflammatory Bowel Diseases: A Nationally Representative Cohort Study. The American Journal Of Gastroenterology 2017, 112: s345. DOI: 10.14309/00000434-201710001-00629.Peer-Reviewed Original ResearchFeasibility of Representing Data from Published Nursing Research Using the OMOP Common Data Model.
Kim H, Choi J, Jang I, Quach J, Ohno-Machado L. Feasibility of Representing Data from Published Nursing Research Using the OMOP Common Data Model. AMIA Annual Symposium Proceedings 2017, 2016: 715-723. PMID: 28269868, PMCID: PMC5333244.Peer-Reviewed Original ResearchConceptsOMOP Common Data ModelNursing intervention protocolPatient reported outcomesCommon data modelReported outcomesDrug treatmentIntervention protocolUnique data itemsNursing articlesData modelNursing researchHealth dataPotential information lossData discoveryUse casesData itemsRepresenting DataFollowInformation lossDisease
2016
- Combination and Pooling of Biomarkers
Zou K, Liu A, Bandos A, Ohno-Machado L, Rockette H. - Combination and Pooling of Biomarkers. 2016, 84-101. DOI: 10.1201/b11031-7.Peer-Reviewed Original Research
2003
Classification of movement states in Parkinson's disease using a wearable ambulatory monitor.
Klapper D, Weaver J, Fernandez H, Ohno-Machado L. Classification of movement states in Parkinson's disease using a wearable ambulatory monitor. AMIA Annual Symposium Proceedings 2003, 2003: 896. PMID: 14728401, PMCID: PMC1480298.Peer-Reviewed Original ResearchConceptsParkinson's patientsMedication-related side effectsDosing of medicationsSymptoms of parkinsonismSeverity of symptomsMedication 1Patient historyParkinson's diseaseSide effectsPatientsCliniciansAmbulatory monitorPatients' selfSymptomsDiseaseMeasurement of movementDaysBradykinesiaMedicationsAkinesiaDyskinesiaHypokinesiaParkinsonismDosingSeverity
1993
Prognostic classification for aids patients in Brazil
Ohno-Machado L. Prognostic classification for aids patients in Brazil. Journal Of Medical Systems 1993, 17: 163-172. PMID: 8254260, DOI: 10.1007/bf00996941.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAgedAIDS-Related Opportunistic InfectionsBrazilCause of DeathChildChild, PreschoolCross-Sectional StudiesDeveloping CountriesDiscriminant AnalysisFemaleHospitalizationHumansIncidenceInfantInfant, NewbornMaleMiddle AgedNeoplasmsSurvival RateConceptsHospitalized AIDS patientsPrognosis of deathHistory of transfusionGroup IV patientsNumber of infectionsEsophageal candidiasisIV patientsAIDS patientsFirst manifestationAID patientsRisk groupsPrognostic classificationPrognostic variablesSurvival ratePatientsFinal discriminant functionInfectionDiseaseDeathAnalysis groupHospitalizationTransfusionPrognosisGroupCandidiasis