2017
Blockchain distributed ledger technologies for biomedical and health care applications
Kuo T, Kim H, Ohno-Machado L. Blockchain distributed ledger technologies for biomedical and health care applications. Journal Of The American Medical Informatics Association 2017, 24: 1211-1220. PMID: 29016974, PMCID: PMC6080687, DOI: 10.1093/jamia/ocx068.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHealth care domainHealth care applicationsBlockchain technologyLedger technologyCare domainFeatures of blockchainBenefits of blockchainCare applicationsFamous BitcoinInformatics researchersBlockchainTechnologyApplicationsCovered topicsBitcoinDomainLatest applicationsPotential challengesDatabase
2014
PhenDisco: phenotype discovery system for the database of genotypes and phenotypes
Doan S, Lin K, Conway M, Ohno-Machado L, Hsieh A, Feupe S, Garland A, Ross M, Jiang X, Farzaneh S, Walker R, Alipanah N, Zhang J, Xu H, Kim H. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. Journal Of The American Medical Informatics Association 2014, 21: 31-36. PMID: 23989082, PMCID: PMC3912702, DOI: 10.1136/amiajnl-2013-001882.Peer-Reviewed Original ResearchConceptsNew information retrieval systemInformation retrieval systemsInformation retrieval toolsDatabase of GenotypesText processing toolsRetrieval systemSearch scenariosDiscovery systemRetrieval toolsAuthorized usersNon-standardized wayCross-study validationSearch comparisonProcessing toolsPromising performanceUsersPhenotype informationDatabaseInformationBiotechnology InformationQueriesMetadataEntrezResourcesSystem
2013
Identifying inference attacks against healthcare data repositories.
Vaidya J, Shafiq B, Jiang X, Ohno-Machado L. Identifying inference attacks against healthcare data repositories. AMIA Joint Summits On Translational Science Proceedings 2013, 2013: 262-6. PMID: 24303279, PMCID: PMC3845790.Peer-Reviewed Original Research
2012
Setting Up an Intronic miRNA Database
Hinske L, Heyn J, Galante P, Ohno-Machado L, Kreth S. Setting Up an Intronic miRNA Database. Methods In Molecular Biology 2012, 936: 69-76. PMID: 23007499, DOI: 10.1007/978-1-62703-083-0_5.Peer-Reviewed Original ResearchConceptsAvailable information resourcesWeb-based toolInformation resourcesGenome-wide analysisHost gene transcriptionAnalysis techniquesIntergenic miRNAsIntragenic microRNAsWide analysisUseful analysis techniqueHost genesMiRNA databaseGene transcriptionMiRNA dataDifferent analysis techniquesMiRNAsSignificant attentionTranscriptionDatabaseMore informationRecent pastBasic structureTechniqueUnique linkageGenesData Locked Inside Databases: A Text Classification In The Database Of Genotypes And Phenotypes (dbGaP) To Address Challenges In Retrieving Clinical Information From Public Data Repositories
Ross M, Kim J, Lin K, Ohno-Machado L, Finn P, Kim H. Data Locked Inside Databases: A Text Classification In The Database Of Genotypes And Phenotypes (dbGaP) To Address Challenges In Retrieving Clinical Information From Public Data Repositories. 2012, a5777-a5777. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5777.Peer-Reviewed Original Research
2011
Quantifying fine-grained privacy risk and representativeness in medical data
Jiang X, Cheng S, Ohno-Machado L. Quantifying fine-grained privacy risk and representativeness in medical data. 2011, 64-67. DOI: 10.1145/2023582.2023594.Peer-Reviewed Original Research
2004
Protecting patient privacy by quantifiable control of disclosures in disseminated databases
Ohno-Machado L, Silveira P, Vinterbo S. Protecting patient privacy by quantifiable control of disclosures in disseminated databases. International Journal Of Medical Informatics 2004, 73: 599-606. PMID: 15246040, DOI: 10.1016/j.ijmedinf.2004.05.002.Peer-Reviewed Original ResearchConceptsSensitive patient dataPattern recognition algorithmsLevel of confidentialitySensitive dataPrivacy protectionSensitive informationDisseminated dataRecognition algorithmDegree of anonymityPatient privacyAlgorithmPrivacyPatient dataDatabaseAnonymizationQuantifiable controlPublic health purposesConfidentialityInformationAnonymityHealth care organizationsHealth purposesCare organizationsCommon practiceAmbiguation
2002
Disambiguation Data: Extracting Information from Anonymized Sources
Dreiseitl S, Vinterbo S, Ohno-Machado L. Disambiguation Data: Extracting Information from Anonymized Sources. Journal Of The American Medical Informatics Association 2002, 9: s110-s114. PMCID: PMC419432, DOI: 10.1197/jamia.m1240.Peer-Reviewed Original Research
2001
Disambiguation data: extracting information from anonymized sources.
Dreiseitl S, Vinterbo S, Ohno-Machado L. Disambiguation data: extracting information from anonymized sources. AMIA Annual Symposium Proceedings 2001, 144-8. PMID: 11825171, PMCID: PMC2243291.Peer-Reviewed Original Research
1999
Using Boolean reasoning to anonymize databases
Øhrn A, Ohno-Machado L. Using Boolean reasoning to anonymize databases. Artificial Intelligence In Medicine 1999, 15: 235-254. PMID: 10206109, DOI: 10.1016/s0933-3657(98)00056-6.Peer-Reviewed Original ResearchConceptsBoolean reasoningMedical data repositoriesMeasure of anonymitySensitive dataPrivacy issuesDatabase fieldAmount of trustConfidential informationDegree of anonymityData repositoryDeterministic inferenceIndividual objectsAnonymityParticular pieceAlgorithmElectronic medical recordsSpecific needsReasoningDatabasePossible misuseAnonymizationInformationRepositoryOutside worldIssues
1997
A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database.
Ohno-Machado L, Boxwala A, Ehresman J, Smith D, Greenes R. A virtual repository approach to clinical and utilization studies: application in mammography as alternative to a national database. AMIA Annual Symposium Proceedings 1997, 369-73. PMID: 9357650, PMCID: PMC2233552.Peer-Reviewed Original ResearchConceptsMammography databaseVisualization of resultsHeterogeneous databasesFederated databasesCentralized architectureExploratory analysis toolLegacy systemsCommon queriesPrototype systemQueriesVirtual repositoryAlternative architecturesImmediate displayDifferent databasesArchitectureAnalysis toolsMammography dataUse of dataRepositoryMammography reportsDatabaseUsersDownloadSystemVisualization