2021
Ultrafast homomorphic encryption models enable secure outsourcing of genotype imputation
Kim M, Harmanci A, Bossuat J, Carpov S, Cheon J, Chillotti I, Cho W, Froelicher D, Gama N, Georgieva M, Hong S, Hubaux J, Kim D, Lauter K, Ma Y, Ohno-Machado L, Sofia H, Son Y, Song Y, Troncoso-Pastoriza J, Jiang X. Ultrafast homomorphic encryption models enable secure outsourcing of genotype imputation. Cell Systems 2021, 12: 1108-1120.e4. PMID: 34464590, PMCID: PMC9898842, DOI: 10.1016/j.cels.2021.07.010.Peer-Reviewed Original ResearchConceptsHomomorphic encryption techniqueResource-intensive computationsSecure outsourcingGenomic data analysisData securityEncryption modelEncryption techniquePrivacy concernsSource codeMemory requirementsGenetic data analysisData analysisComparable accuracyFundamental stepGenotype imputationImputationDownloadSecurityOutsourcingComputationCodeServicesRequirementsAccuracyMethod
2020
COVID-19 TestNorm: A tool to normalize COVID-19 testing names to LOINC codes
Dong X, Li J, Soysal E, Bian J, DuVall S, Hanchrow E, Liu H, Lynch K, Matheny M, Natarajan K, Ohno-Machado L, Pakhomov S, Reeves R, Sitapati A, Abhyankar S, Cullen T, Deckard J, Jiang X, Murphy R, Xu H. COVID-19 TestNorm: A tool to normalize COVID-19 testing names to LOINC codes. Journal Of The American Medical Informatics Association 2020, 27: 1437-1442. PMID: 32569358, PMCID: PMC7337837, DOI: 10.1093/jamia/ocaa145.Peer-Reviewed Original ResearchConceptsElectronic health recordsLOINC codesSecondary useRule-based toolOnline web applicationOpen-source packageCritical data elementsWeb applicationData networksEnd usersData elementsIndependent test setHealth recordsTest setKey challengesData normalizationCritical resourcesTest namesRoutine clinical practice dataCodeClinical practice dataCoronavirus disease 2019COVID-19 diagnostic testsToolDevelopers