2018
Development and Validation of a Multiparameterized Artificial Neural Network for Prostate Cancer Risk Prediction and Stratification
Roffman DA, Hart GR, Leapman MS, Yu JB, Guo FL, Ali I, Deng J. Development and Validation of a Multiparameterized Artificial Neural Network for Prostate Cancer Risk Prediction and Stratification. JCO Clinical Cancer Informatics 2018, 2: 1-10. PMID: 30652591, PMCID: PMC6873987, DOI: 10.1200/cci.17.00119.Peer-Reviewed Original ResearchConceptsProstate Cancer Risk PredictionCancer risk predictionPositive predictive valueProstate cancerRisk predictionPredictive valueHistory of strokeHigh-risk subgroupsBody mass indexCancer risk stratificationHealth informationPersonal health informationPrimary prostate cancerYears of ageDiabetes statusRisk stratificationSmoking statusMass indexCancer populationHeart diseaseExercise habitsCancer riskHigh riskCutoff valueAdult survey data
2011
Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer
Deng J, Chen Z, Yu JB, Roberts KB, Peschel RE, Nath R. Testicular Doses in Image-Guided Radiotherapy of Prostate Cancer. International Journal Of Radiation Oncology • Biology • Physics 2011, 82: e39-e47. PMID: 21489702, DOI: 10.1016/j.ijrobp.2011.01.071.Peer-Reviewed Original ResearchConceptsImage-guided radiotherapyTesticular dosesFull-fan modeProstate cancerFemoral headLess doseCBCT scansHalf-fan modeProstate cancer patientsKilovoltage cone-beamCancer patientsIntensity-modulated radiotherapy (IMRT) treatmentKilovoltage CBCTSuperior-inferior directionCone beamDosesCBCT fieldProstate patientsRectumDoseProstateMore doseRadiotherapy treatmentPatientsRadiotherapy
2009
Impact of Kilo-Voltage Cone Beam Computed Tomography on Image-Guided Radiotherapy of Prostate Cancer
Deng J, Chen Z, Nath R. Impact of Kilo-Voltage Cone Beam Computed Tomography on Image-Guided Radiotherapy of Prostate Cancer. IFMBE Proceedings 2009, 25/1: 17-20. DOI: 10.1007/978-3-642-03474-9_5.Peer-Reviewed Original ResearchKilo-voltage cone beamProstate cancerImage-guided radiotherapyDosevolume histogramsExcessive dosesCone beamFemur headAdjacent critical structuresPatient anatomyTesticular doseCBCT dosesTesticular dosesImage-guided radiation therapyRadiation therapyMost dosesSuperior-inferior directionDVH analysisCritical organsCancerDosesIGRT treatmentReal patient anatomyDosimetric impactScanning protocolPosterior side
2008
SU‐GG‐T‐493: Dosimetric Impact of Beam Energy and Number of Photon Fields On Prostate Dose Distributions: Inverse Planning and Validation Study
Ahmad M, Lund M, Halpin H, Deng J, Chen Z, Mani S, Moran M, Nath R. SU‐GG‐T‐493: Dosimetric Impact of Beam Energy and Number of Photon Fields On Prostate Dose Distributions: Inverse Planning and Validation Study. Medical Physics 2008, 35: 2838-2838. DOI: 10.1118/1.2962242.Peer-Reviewed Original ResearchPlanning target volumeComputerized tomographyTreatment planIMRT techniqueTarget volumeNormal tissuesIrradiated normal tissueDose distributionSuperior dose distributionProstate target volumeInverse planningProstate cancerProstate carcinomaLesser dosesSample patientsBeam arrangementsDose constraintsDosimetric differencesPatientsDose uniformityProstate patientsIMRT plansDosimetric impactIntegral doseInverse planning process
2007
On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy
Chen ZJ, Deng J, Roberts K, Nath R. On the Need to Compensate for Edema-Induced Dose Reductions in Preplanned 131Cs Prostate Brachytherapy. International Journal Of Radiation Oncology • Biology • Physics 2007, 70: 303-310. PMID: 17980500, PMCID: PMC2289996, DOI: 10.1016/j.ijrobp.2007.09.007.Peer-Reviewed Original ResearchConceptsDose reductionProstate brachytherapyDose compensationLarge edemaBiochemical recurrence-free survivalRecurrence-free survivalSignificant dose reductionEffects of edemaSublethal damage repairAdditional irradiationPrescription doseProstate cancerIndividual patientsEdemaEdema evolutionPrescribed doseProstate edemaEffective doseRadiobiologic effectsBrachytherapyDoseProstate implantsDose responseImplantsA Two-Stage IMRT Treatment Protocol Provides More Robust Radiotherapy for Prostate Cancer in Presence of Inter- and Intra-Fractional Organ Motions
Chen Z, Deng J, Nath R, Peschel R. A Two-Stage IMRT Treatment Protocol Provides More Robust Radiotherapy for Prostate Cancer in Presence of Inter- and Intra-Fractional Organ Motions. International Journal Of Radiation Oncology • Biology • Physics 2007, 69: s713-s714. DOI: 10.1016/j.ijrobp.2007.07.2100.Peer-Reviewed Original Research