2020
Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy
Ye F, Cho H, Rouayheb S. Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy. 2020, 00: 902-907. DOI: 10.1109/isit44484.2020.9174492.Peer-Reviewed Original ResearchInformation-theoretic privacyGenomic data sharingCritical health-related informationEfficient algorithmic implementationHidden Markov ModelPersonal genomics servicesData sharingGenomic privacyPrivacyAlgorithmic implementationSuch servicesHealth-related informationStraightforward solutionMarkov modelGenomic dataServicesGenomic servicesInformationSharingImplementationCorrelation structureData
2015
Exploiting ontology graph for predicting sparsely annotated gene function
Wang S, Cho H, Zhai C, Berger B, Peng J. Exploiting ontology graph for predicting sparsely annotated gene function. Bioinformatics 2015, 31: i357-i364. PMID: 26072504, PMCID: PMC4542782, DOI: 10.1093/bioinformatics/btv260.Peer-Reviewed Original ResearchConceptsFunction prediction algorithmsPrediction algorithmVariety of algorithmsFunctional labelsOntology graphCross-validation experimentsOverfitting problemGraph structurePrevious stateGene functionAlgorithmAnnotation catalogsTens of thousandsMolecular interaction networksFunction predictionOntology databasePoor predictive performanceAnnotationLabelsPredictive performanceGene Ontology databaseInformationLarge numberGO termsInteraction networks