Effects of ospemifene on the female reproductive and urinary tracts
Archer DF, Carr BR, Pinkerton JV, Taylor HS, Constantine GD. Effects of ospemifene on the female reproductive and urinary tracts. Menopause The Journal Of The North American Menopause Society 2015, 22: 786-796. PMID: 25423325, PMCID: PMC4481022, DOI: 10.1097/gme.0000000000000365.Peer-Reviewed Original ResearchConceptsEstrogen receptor agonist/antagonistReceptor agonists/antagonistsAgonists/antagonistsVaginal atrophyVaginal tissueSelective estrogen receptor modulatorsEffects of ospemifenePostmenopausal women's healthRelief of symptomsEstrogen receptor modulatorsAgonist/antagonist effectsUrinary tract tissuesHormone-responsive tissuesTissue-dependent responseEndometrial histopathologyEndometrial safetyEstrogen therapyClinical effectsTransvaginal ultrasoundMenopausal symptomsUrinary tractPreclinical dataCytologic examinationVaginal effectsPreclinical models
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