Interferon‐γ expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway
Rincón M, Enslen H, Raingeaud J, Recht M, Zapton T, Su M, Penix L, Davis R, Flavell R. Interferon‐γ expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway. The EMBO Journal 1998, 17: 2817-2829. PMID: 9582275, PMCID: PMC1170622, DOI: 10.1093/emboj/17.10.2817.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalcium-Calmodulin-Dependent Protein KinasesCell DivisionEnzyme InhibitorsImidazolesInterferon-gammaLymphocyte ActivationMAP Kinase Kinase 6MiceMice, Inbred C3HMice, Inbred C57BLMice, TransgenicMitogen-Activated Protein Kinasesp38 Mitogen-Activated Protein KinasesPyridinesSignal TransductionTh1 CellsTh2 CellsTranscription, GeneticConceptsP38 MAP kinase pathwayMAP kinase pathwayP38 MAP kinaseMAP kinaseKinase pathwayMAP kinase kinase 6Pyridinyl imidazole compoundsGrowth factor-induced proliferationIFNgamma promoterMammalian cellsSignal transductionEnvironmental stressTransgenic miceTh1 cellsKinase resultsKinase 6Molecular mechanismsTh2 cellsCellular responsesKinaseCell deathInflammatory responseT cellsImmune responsePathway
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