2025
FlgY, PflA, and PflB form a spoke–ring network in the high-torque flagellar motor of Helicobacter pylori
Tachiyama S, Rosinke K, Khan M, Zhou X, Xin Y, Botting J, Yue J, Roujeinikova A, Hoover T, Liu J. FlgY, PflA, and PflB form a spoke–ring network in the high-torque flagellar motor of Helicobacter pylori. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2421632122. PMID: 40261933, PMCID: PMC12054838, DOI: 10.1073/pnas.2421632122.Peer-Reviewed Original ResearchConceptsMS ringAccessory proteinsStator complexWild-type <i>H. pyFlagellar motorSalmonella enterica</i>Protein-protein interactionsFlagellar motilityAlphaFold-predicted structuresFlgIBiochemical approachesPflBGastric mucus layerMolecular geneticsPFLACryoelectron tomographyUnique motilityBacterial flagellar motorMucus layerMotilityBacteriaProteinHuman stomachPseudoatomic modelHelicobacter pylori
2010
P22 Coat Protein Structures Reveal a Novel Mechanism for Capsid Maturation: Stability without Auxiliary Proteins or Chemical Crosslinks
Parent KN, Khayat R, Tu LH, Suhanovsky MM, Cortines JR, Teschke CM, Johnson JE, Baker TS. P22 Coat Protein Structures Reveal a Novel Mechanism for Capsid Maturation: Stability without Auxiliary Proteins or Chemical Crosslinks. Structure 2010, 18: 390-401. PMID: 20223221, PMCID: PMC2951021, DOI: 10.1016/j.str.2009.12.014.Peer-Reviewed Original ResearchConceptsP22 coat proteinCoat proteinAuxiliary proteinsCoat protein structureCryo-electron microscopyN-terminal helixBacteriophage P22 coat proteinViral capsid assemblyDsDNA phagesPseudoatomic modelCapsid maturationP-loopProtein structureCapsid stabilizationIntersubunit interactionsCapsid assemblyComparative modelingNovel mechanismProteinTrypsin digestionSubunit additionGold labelingChemical crosslinksMaturationAssembly
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