Application of CRISPR/Cas Genomic Editing Tools for HIV Therapy: Toward Precise Modifications and Multilevel Protection
Maslennikova A, Mazurov D. Application of CRISPR/Cas Genomic Editing Tools for HIV Therapy: Toward Precise Modifications and Multilevel Protection. Frontiers In Cellular And Infection Microbiology 2022, 12: 880030. PMID: 35694537, PMCID: PMC9177041, DOI: 10.3389/fcimb.2022.880030.Peer-Reviewed Original ResearchConceptsHIV therapyViral resistance to therapyResistance to HIV infectionLatent HIV reservoirResistance to therapyMature B cellsKnock-in (KIHIV reservoirLatent HIVAntiretroviral therapyHIV infectionViral coreceptorsViral escapeFusion inhibitory peptidesDrug toxicityB cellsNeutralizing antibodiesHAARTProviral DNATherapyProvirus excisionTherapeutic methodsHIVInhibitory peptidesGene editing
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