Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
Huhn O, Ivarsson M, Gardner L, Hollinshead M, Stinchcombe J, Chen P, Shreeve N, Chazara O, Farrell L, Theorell J, Ghadially H, Parham P, Griffiths G, Horowitz A, Moffett A, Sharkey A, Colucci F. Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy. Nature Communications 2020, 11: 381. PMID: 31959757, PMCID: PMC6971012, DOI: 10.1038/s41467-019-14123-z.Peer-Reviewed Original ResearchConceptsDecidual innate lymphoid cellsKiller-cell immunoglobulin-like receptorsFetal extravillous trophoblastsInnate lymphoid cellsExtravillous trophoblastNK cellsEarly pregnancyLymphoid cellsFunction of innate lymphoid cellsPeripheral blood NK cellsHLA class I ligandsMaternal dendritic cellsBlood NK cellsDecidual NK cellsGranzyme B levelsProliferating NK cellsImmunoglobulin-like receptorsClass I ligandsIncreased chemokine productionDecidual NKHuman deciduaMaternal cellsDendritic cellsPlacental developmentChemokine production
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