2023
Platelet response to influenza vaccination reflects effects of aging
Konstorum A, Mohanty S, Zhao Y, Melillo A, Vander Wyk B, Nelson A, Tsang S, Blevins T, Belshe R, Chawla D, Rondina M, Gill T, Montgomery R, Allore H, Kleinstein S, Shaw A. Platelet response to influenza vaccination reflects effects of aging. Aging Cell 2023, 22: e13749. PMID: 36656789, PMCID: PMC9924941, DOI: 10.1111/acel.13749.Peer-Reviewed Original ResearchConceptsCommunity-dwelling older adultsPlatelet activationOlder adultsInfluenza vaccinationAge-associated chronic inflammationInfluence platelet functionRNA expressionPro-inflammatory diseasesAge-associated increasePlatelet activation pathwaysAge-associated differencesActivation pathwayPlatelet transcriptomeGeriatric conditionsChronic inflammationImmune responsePlatelet functionPlatelet responseSNF residentsVaccinationActivation responseYoung individualsProtein levelsAdultsYounger participants
2019
miR-45la Inhibition Reduces Established Endometriosis Lesions in Mice
Li M, Zhou Y, Taylor HS. miR-45la Inhibition Reduces Established Endometriosis Lesions in Mice. Reproductive Sciences 2019, 26: 1506-1511. PMID: 31354069, DOI: 10.1177/1933719119862050.Peer-Reviewed Original ResearchConceptsMiR-451a inhibitorReproductive-age womenTreatment of endometriosisPro-inflammatory diseasesSystemic treatmentEndometriosis lesionsIL-6Chronic diseasesPromising therapyCurrent treatmentMicroRNA-451aMurine modelSex steroidsEndometriosisLesion sizeVisible lesionsMiR-451aMicroRNAs treatmentsDiseaseAltered expressionΒ-cateninTreatmentLesionsInhibitorsMultiple pathways
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