2025
Pregnenolone effects on parasympathetic response to stress and alcohol cue provocation in treatment‐seeking individuals with alcohol use disorder
Gao H, Sinha R, Wemm S, Milivojevic V. Pregnenolone effects on parasympathetic response to stress and alcohol cue provocation in treatment‐seeking individuals with alcohol use disorder. Alcohol Clinical And Experimental Research 2025, 49: 619-628. PMID: 39779217, PMCID: PMC11928267, DOI: 10.1111/acer.15529.Peer-Reviewed Original ResearchConceptsAlcohol use disorderTreatment-seeking individualsAlcohol cuesAlcohol cravingResponse to stressPregnenolone groupUse disorderResponse to alcohol cuesGroup x condition interactionHigher alcohol cravingLinear mixed-effects modelsHeart rate variabilityHeart rate variability indicesAutonomic nervous system dysregulationChronic alcohol consumptionRandomized to placeboAutonomic nervous system responsesNervous system dysregulationCravingAlcohol's impactCondition interactionAssociated with autonomic nervous system dysregulationNervous system responsesAutonomic responsesEnhanced autonomic function
2023
Autonomic nervous system responses to social stimuli among autistic individuals: A systematic review and meta‐analysis
Zadok E, Golan O, Lavidor M, Gordon I. Autonomic nervous system responses to social stimuli among autistic individuals: A systematic review and meta‐analysis. Autism Research 2023, 17: 497-511. PMID: 38073185, DOI: 10.1002/aur.3068.Peer-Reviewed Original ResearchAutonomic nervous system responsesNervous system responsesParasympathetic nervous system activityNervous system activityParasympathetic systemAutonomic regulationPhysiological responsesSystematic reviewAutonomic responsesAutistic individualsAutonomic functioningNT individualsSystem activitySocial stimuliSignificant differencesStudy objectiveOverall differenceHigh heterogeneityPhysiological functionsCurrent study
2019
Drug-induced stress responses and addiction risk and relapse
Wemm SE, Sinha R. Drug-induced stress responses and addiction risk and relapse. Neurobiology Of Stress 2019, 10: 100148. PMID: 30937354, PMCID: PMC6430516, DOI: 10.1016/j.ynstr.2019.100148.Peer-Reviewed Original ResearchDrug useDrug-induced stress responsesAddiction riskCo-occurring drug usePeripheral stress responsesAutonomic nervous system responsesNervous system responsesDrug use historyChronic drug useChronic drug usersAdrenal axisAcute effectsEvidence of alterationsDrug usersTonic levelsGlucocorticoid responseBinge/Prefrontal cortexDifferent drugsPsychoactive drugsDrug seekingDrugsStress responseRelapseHuman research
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