2025
Assessing patient withdrawal in cancer clinical trials: A systematic evaluation of reasons and transparency in reporting.
Argulian A, Karol A, Paredes R, Oguntuyo K, Weintraub L, Miller J, Fujiwara Y, Joshi H, Doroshow D, Galsky M. Assessing patient withdrawal in cancer clinical trials: A systematic evaluation of reasons and transparency in reporting. Journal Of Clinical Oncology 2025, 43 DOI: 10.1200/jco.2025.43.16_suppl.e23003.Peer-Reviewed Original ResearchCancer clinical trialsOncology clinical trialsPhase III oncology clinical trialsSupportive care trialsPatient withdrawalClinical trialsLack of standard practicesPrimary cancer typeCare trialsFollow-upPatient-initiatedHigh attrition ratesPatients' intentionStandard careCONSORT diagramControl armDocumented reasonsOncology trialsAttrition ratesMedian Follow-UpTrial integrityWithdrawal reasonsConsent documentsTrial designSelection bias
2024
Modern Photon-Based Craniospinal Irradiation in Leptomeningeal Disease
Keit E, Peterson J, Johnstone P, Robinson T, Figura N. Modern Photon-Based Craniospinal Irradiation in Leptomeningeal Disease. International Journal Of Radiation Oncology • Biology • Physics 2024, 120: e242. DOI: 10.1016/j.ijrobp.2024.07.542.Peer-Reviewed Original ResearchIntensity Modulated RadiotherapyCraniospinal irradiationLeptomeningeal diseaseHematologic malignanciesSolid tumorsOverall survivalProton therapyLocal failureAssociated with improved OSDelay systemic therapyG3+ toxicitySymptomatic leptomeningeal diseaseSite of spreadKaplan Meier methodPhoton-based treatmentsPrimary cancer typeAcute gradeG3 fatigueMedian OSModulated radiotherapyNeutropenic feverMedian followPalliative radiotherapyDisseminated diseaseSystemic therapy
2021
Characteristics of Online Crowdfunding Campaigns for Urological Cancers in the United States
Holler J, Hakam N, Nabavizadeh B, Sadighian M, Shibley W, Li K, Weiser L, Rios N, Enriquez A, Leapman M, Amend G, Breyer B. Characteristics of Online Crowdfunding Campaigns for Urological Cancers in the United States. Urology Practice 2021, 9: 56-63. PMID: 37145560, DOI: 10.1097/upj.0000000000000275.Peer-Reviewed Original ResearchUrological cancersActive treatmentCancer campaignsMajor urological cancersPrimary cancer typeCross-sectional studyWilcoxon rank sum testRank sum testRecipient ageMultivariable analysisPatient populationTesticular malignancyMalignancy typeTesticular cancerKidney cancerMedical careCancerCancer typesMedical expensesFinancial burdenOutcomesBladderKruskal-WallisProstateAgeTumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF
Cheok SK, Narayan A, Arnal-Estape A, Gettinger S, Goldberg SB, Kluger HM, Nguyen D, Patel A, Chiang V. Tumor DNA Mutations From Intraparenchymal Brain Metastases Are Detectable in CSF. JCO Precision Oncology 2021, 5: 163-172. PMID: 34250381, PMCID: PMC8232069, DOI: 10.1200/po.20.00292.Peer-Reviewed Original ResearchConceptsIntraparenchymal brain metastasesBrain metastasesCell-free DNAExtracranial tumorsBrain metastasis tissuesProgressive brain metastasesThird of patientsNormal pressure hydrocephalusTumor DNA mutationsPrimary cancer typeAnalysis of CSFSamples of CSFLeptomeningeal diseaseEffective surrogate markerBrain biopsyPressure hydrocephalusLumbar punctureSurrogate markerCancer-associated genesMetastasis tissuesPatientsMetastasisDiscordant responsesRenal cellsGenomic profiling
2020
35. EVALUATING CSF CIRCULATING TUMOR DNA IN INTRAPARENCHYMAL BRAIN METASTASIS
Cheok S, Narayan A, Arnal-Estape A, Patel A, Nguyen D, Chiang V. 35. EVALUATING CSF CIRCULATING TUMOR DNA IN INTRAPARENCHYMAL BRAIN METASTASIS. Neuro-Oncology Advances 2020, 2: ii6-ii6. PMCID: PMC7401400, DOI: 10.1093/noajnl/vdaa073.023.Peer-Reviewed Original ResearchIntraparenchymal brain metastasesBrain metastasis tissuesNormal pressure hydrocephalusBrain metastasesCerebrospinal fluidLeptomeningeal diseaseCell-free DNACSF ctDNAMetastasis tissuesTumor DNASamples of CSFStudy 12 patientsPrimary cancer typeAnalysis of CSFIntraparenchymal diseaseFurther therapySystemic metastasesPlasma ctDNASixteen patientsIntraparenchymal tumorsPressure hydrocephalusColorectal cancerLumbar punctureDetection of novelCancer-associated genes
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