Induction of a program gene expression during osteoblast differentiation with strontium ranelate
Zhu L, Zaidi S, Peng Y, Zhou H, Moonga B, Blesius A, Dupin-Roger I, Zaidi M, Sun L. Induction of a program gene expression during osteoblast differentiation with strontium ranelate. Biochemical And Biophysical Research Communications 2007, 355: 307-311. PMID: 17300752, DOI: 10.1016/j.bbrc.2007.01.120.Peer-Reviewed Original ResearchConceptsStrontium ranelateBone sialoproteinCFU-OBEffects of strontium ranelateOsteoblast differentiationTreatment of osteoporosisGene expressionConcentration-dependent increaseStimulate bone formationColony-forming unit-osteoblastsBone marrow-derived stromal cellsMarrow-derived stromal cellsExpression of Runx2Increased osteoblast differentiationRanelateProgram of gene expressionStromal cellsPre-osteoblast cellsCell type-specificOB-6 cellsBone formationExperimental modelOsteocalcinProgrammed gene expressionType-specific
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