C–H bond activation and sequential addition to two different coupling partners: a versatile approach to molecular complexity
Brandes DS, Ellman JA. C–H bond activation and sequential addition to two different coupling partners: a versatile approach to molecular complexity. Chemical Society Reviews 2022, 51: 6738-6756. PMID: 35822540, PMCID: PMC9364435, DOI: 10.1039/d2cs00012a.Peer-Reviewed Original ResearchConceptsAddition reactionH bondsMolecular complexityAtom-economical reactionH bond activationH bond additionSingle reaction sequenceBond activationΣ-bondBond additionCarbonyl compoundsΠ bondsΠ-systemType of functionalityStereochemical controlCoupling partnersMild conditionsSubsequent couplingReaction sequenceVersatile approachDifferent coupling partnersReagentsSequential additionMore complex structuresReaction
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