Stress-related reduction of hippocampal subfield volumes in major depressive disorder: A 7-Tesla study
Alper J, Feng R, Verma G, Rutter S, Huang K, Xie L, Yushkevich P, Jacob Y, Brown S, Kautz M, Schneider M, Lin H, Fleysher L, Delman B, Hof P, Murrough J, Balchandani P. Stress-related reduction of hippocampal subfield volumes in major depressive disorder: A 7-Tesla study. Frontiers In Psychiatry 2023, 14: 1060770. PMID: 36816419, PMCID: PMC9932898, DOI: 10.3389/fpsyt.2023.1060770.Peer-Reviewed Original ResearchMajor depressive disorderTreatment-resistant depressionMajor depressive disorder patientsAutomatic Segmentation of Hippocampal SubfieldsHippocampal subfield volumesSubfield volumesHippocampal subfieldsDepressive disorderHealthy controlsTreatment-resistant depressed patientsMechanisms of depressionStress-related reductionHigh-resolution MRI dataSegmentation of hippocampal subfieldsEffects of stressSymptom scoresLeft CA1Automated hippocampal segmentationVolumetric differencesDepressionChecklist scoresExploratory analysisPrevalent health problemHippocampal segmentationComplex pathophysiology
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