Noninvasive Monitoring of Immunosuppressive Drug Efficacy to Prevent Rejection of Intracerebral Glial Precursor Allografts
Gorelik M, Janowski M, Galpoththawela C, Rifkin R, Levy M, Lukomska B, Kerr D, Bulte J, Walczak P, Morgan R. Noninvasive Monitoring of Immunosuppressive Drug Efficacy to Prevent Rejection of Intracerebral Glial Precursor Allografts. Cell Transplantation 2012, 21: 2149-2157. PMID: 22508097, DOI: 10.3727/096368912x636911.Peer-Reviewed Original ResearchConceptsCentral nervous systemBioluminescence imagingAutologous transplanted cellsDevelopment of cell-based therapiesCombination of rapamycinLong-term survivalCell-based therapiesDevelopment of patient-specificGraft toleranceImmunocompetent miceCell transplantationGraft rejectionGlial-restricted progenitorsCell rejectionImmunodeficient animalsPrevent rejectionImmunosuppressed miceImmunocompetent animalsCyclosporin AGrafted areaTransplanted cellsAllograftDrug efficacyInflammatory processMyriad of diseases
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