2024
Chronic overlapping pain conditions and nociplastic pain
Johnston K, Signer R, Huckins L. Chronic overlapping pain conditions and nociplastic pain. Human Genetics And Genomics Advances 2024, 6: 100381. PMID: 39497418, PMCID: PMC11617767, DOI: 10.1016/j.xhgg.2024.100381.Peer-Reviewed Original ResearchGenome wide association studiesTranscriptome-wide associationChronic overlapping pain conditionsTissue enrichment analysisSingle nucleotide polymorphismsEnrichment analysisNociplastic painPain conditionsIndependent single nucleotide polymorphismsMultisite chronic painGene Set Enrichment AnalysisSNP heritabilityUnique genesNeuropathic pain phenotypesAssociation studiesPolygenic traitChronic pain conditionsGene setsNucleotide polymorphismsMetabolic traitsHeritable traitGenetic overlapPain phenotypesPain descriptorsPain experience
2014
Psychosocial Characteristics and Pain Burden of Patients With Suspected Sphincter of Oddi Dysfunction in the EPISOD Multicenter Trial
Brawman-Mintzer O, Durkalski V, Wu Q, Romagnuolo J, Fogel E, Tarnasky P, Aliperti G, Freeman M, Kozarek R, Jamidar P, Wilcox M, Elta G, Orrell K, Wood A, Mauldin P, Serrano J, Drossman D, Robuck P, Cotton P. Psychosocial Characteristics and Pain Burden of Patients With Suspected Sphincter of Oddi Dysfunction in the EPISOD Multicenter Trial. The American Journal Of Gastroenterology 2014, 109: 436. PMID: 24445573, PMCID: PMC4409683, DOI: 10.1038/ajg.2013.467.Peer-Reviewed Original ResearchConceptsFunctional gastrointestinal disordersPain burdenOddi dysfunctionGender-matched general populationPainful functional gastrointestinal disordersFunctional gallbladder diseaseGreater pain burdenPost-cholecystectomy painHealth-related qualityMental composite scoreAnxiety/depressionBaseline anxiety scoresPsychosocial comorbiditiesMulticenter trialIrritable bowelGastrointestinal disordersGallbladder diseasePain descriptorsPsychosocial assessmentHigh prevalencePsychosocial parametersUS CentersStudy populationPsychosocial disturbancesSevere psychological problems
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