2019
Preoperative frailty and its association with postsurgical pain in an older patient cohort
Esses G, Liu X, Lin H, Khelemsky Y, Deiner S. Preoperative frailty and its association with postsurgical pain in an older patient cohort. Regional Anesthesia & Pain Medicine 2019, 44: 695-699. PMID: 31061107, DOI: 10.1136/rapm-2018-100247.Peer-Reviewed Original ResearchPostsurgical painOlder adultsPreoperative frailtyChronic painElective non-cardiac surgeryPostsurgical chronic painChronic postsurgical painGeriatric Pain MeasureNon-cardiac surgeryPreoperative risk factorsPoor surgical outcomesFrail older adultsOlder patient cohortPostsurgical pain outcomesAssociated with greater oddsNegatively impact recoveryProspective cohort studyQuality of lifePreoperative frailty assessmentPreoperative painSpine surgerySurgical outcomesPhysical functionPain outcomesBaseline characteristics
2018
Age-Related Volumetric Changes in Mandibular Condyles
Safi AF, Kauke M, Grandoch A, Nickenig HJ, Zöller JE, Kreppel M. Age-Related Volumetric Changes in Mandibular Condyles. Journal Of Craniofacial Surgery 2018, 29: 510-513. PMID: 29215439, DOI: 10.1097/scs.0000000000004137.Peer-Reviewed Original ResearchConceptsCone-beam computerized tomographyMandibular condyleOcclusal supportComputerized tomographyCondylar volumeOlder patient cohortOlder patient groupRetrospective chart reviewPosterior occlusal supportSex-specific significant differencesAge-related volumetric changesSignificant differencesStudent's t-testVolumetric measurementsChart reviewPatient groupPatient cohortPathophysiological alterationsPearson correlation testCondylar changesMajority of studiesImportant additional dataCondyleVolumetric analysisT-test
2013
Cisplatin-based combination chemotherapy in septuagenarians with metastatic urothelial cancer
Galsky M, Krege S, Lin C, Hahn N, Ecke T, Moshier E, Sonpavde G, Godbold J, Oh W, Bamias A. Cisplatin-based combination chemotherapy in septuagenarians with metastatic urothelial cancer. Urologic Oncology Seminars And Original Investigations 2013, 32: 30.e15-30.e21. PMID: 23428534, DOI: 10.1016/j.urolonc.2012.11.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsCisplatinClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicCohort StudiesFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm MetastasisSurvival AnalysisTreatment OutcomeUrologic NeoplasmsUrotheliumConceptsCisplatin-based chemotherapyMetastatic urothelial carcinomaElderly patientsUrothelial carcinomaNo significant differenceCisplatin-based first-line chemotherapyCisplatin-based combination chemotherapyPresence of visceral metastasesMetastatic urothelial cancerTreatment-related deathsFirst-line chemotherapyAdequate renal functionBaseline performance statusFirst-line treatmentSignificant differenceProportion of patientsOlder patient cohortIndividual patient dataFebrile neutropeniaVisceral metastasesCombination chemotherapyMedian survivalIII trialsUrothelial cancerPerformance status
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