2021
Genomics of Obsessive-Compulsive Disorder—Toward Personalized Medicine in the Era of Big Data
Szejko N, Dunalska A, Lombroso A, McGuire JF, Piacentini J. Genomics of Obsessive-Compulsive Disorder—Toward Personalized Medicine in the Era of Big Data. Frontiers In Pediatrics 2021, 9: 685660. PMID: 34746045, PMCID: PMC8564378, DOI: 10.3389/fped.2021.685660.Peer-Reviewed Original ResearchPsychiatric Genomics ConsortiumCommon disease-common variant hypothesisCommon variant hypothesisContext of genomicsGenetic codeGenetic association studiesMultiple genesAssociation studiesGenomics ConsortiumPolygenic risk scoresGenomicsGenetic contributionMendelian randomizationPolygenic disorderPersonalized medicineObsessive-compulsive disorderUK BiobankNew pathwayOCD pathogenesisAvailable databasesGenesDisease-specific databasesChina Kadoorie BiobankPathwayCo-existing pathology
2010
The Genetics of Obsessive-Compulsive Disorder.
Bloch MH, Pittenger C. The Genetics of Obsessive-Compulsive Disorder. Current Psychiatry Research And Reviews 2010, 6: 91-103. PMID: 23970845, PMCID: PMC3747631, DOI: 10.2174/157340010791196439.Peer-Reviewed Original ResearchCandidate gene studiesGene studiesGenome-wide association studiesGenome-wide significanceFuture candidate gene studiesHereditable componentTransporter geneAssociation studiesGlutamate transporter geneLarge collaborative effortsGenetic associationLinkage studiesImportant environmental influencesPhenotypic descriptionGenesEnvironmental influencesGeneticsImproved understandingPathwayPopulationMore probandsOCD pathogenesisFamily studies
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